Term
| What is the correct order for flow of information to the brain in regards to a painful stimulus |
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Definition
Stimulus-> nociceptors-->dorsal horn--> brainstem --> thalamus--> cortex-->?-->Pain perception (cortex amygdala_ |
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Term
Fa-1/RA-1 response Where are their receptors located? |
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Definition
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Term
FA-1/RA-1 responses What stimulates these responses? |
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Definition
| It's stimuli is a phasic response (velocity) |
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Term
FA-1/RA-1 receptors allow us to perceive what? And what is the general size of these receptor fields? |
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Definition
movement and texture 2. small receptor fields |
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Term
| SA-1 receptors are located in what structures? |
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Definition
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Term
| What stimulates SA-1 receptors? |
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Definition
| phasic and tonic responses (position)... basically, the APs turn on after the initial change and is at first a higher frequency and then the rate of APs even out |
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Term
What does the SA-1 allow us to perceive? Is the receptor field big or small? |
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Definition
size, shape, sterognosis, and graphestesia large receptor field |
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Term
| FA-II/RA-II receptors are located in what structures? |
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Definition
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Term
| FA-2 receptors are stimulated by what? What does this allow us to perceive? Are the receptor fields big or small? |
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Definition
| Acceleration. This allows us to perceive vibration. Large receptor fields |
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Term
| SA-2 receptors are located in what structures? What stimulates them? Allows us to perceive what? |
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Definition
| Ruffini Corpuscules. They perceive tonic responses (skin stretch). Allow us to perceive proprioception |
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Term
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Definition
| pain is a perception- a connection with nociceptors that is modified by central processes |
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Term
| T or F nociception input can occur with little or no associated pain |
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Definition
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Term
| T or F Pain cannot occur in the abscence of observable nocireceptor input. |
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Definition
| False- pain can appear in the absence of observable peripheral nocireceptor input. |
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Term
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Definition
| In the dermis of hairy skin, this type of receptor carries FA-I fibers |
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Term
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Definition
| In the dermis of hairy skin these nerves hold temperature and nociceptor receptors... |
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Term
| The density of FA-1 ands SA-1 receptors are in highest density where? |
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Definition
| in the finger tips and gradually decreas in numbers as you move proximally towards the wrist |
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Term
| The palm of the hand has a lower concentration of receptor endings than the finger tips and therefore has a lower or higher perceptual threshold? |
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Definition
the palm has a higher perceptual threshold than the fingertips because perceptual threshold is reached when the probability of a person sensing something reaches 50%. because you have more nerves in the fingertips than in the palm- you can sense something touchign your fingertips at a much lower threshold than in the palm. * perceptual threshold matches neural threshold |
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Term
| What structure in the dermis contains nerve receptors that allow us to detect slippage, which ultimately enables us to adjust our grip? |
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Definition
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Term
| Does stimulation of SAII lead to a conscious sensation? |
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Definition
| No. SA-II stimulation may be attributed to sense of limb position |
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Term
FA-1 receptor endings (Meisner's corpuscule) detect vibration at lower or higher frequncies than FA-2 receptor endings (pacinian) |
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Definition
| FA1 (Meisner) detect vibrations of low frequency, while FA-2 (Pacinian) detect vibrations at high frequencies. |
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Term
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Definition
The temperature at which nociceptors take over for warm fibers and lead to sensation of pain (rather than heat) |
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Term
| Substance P, CGRP, and GLU |
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Definition
| What is released by nocireceptor fibers when they respond to chemicals in damaged tissue |
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Term
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Definition
nociceptors that signal slow burning pain (unmyelinated fibers) |
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Term
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Definition
nociceptors that signal fast, pricking pain (myelinated and small) |
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Term
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Definition
greater pain perception with same nociceptive input. caused by prolonged activation of C-fibers--> releases peptidases peripherally--> inflammation-> sensitization of nerves--> produces increased input to CNS from same stimulation --> increased perception of pain |
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Term
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Definition
| in dorsal horn prolonged and increased input potentiates NMDA receptors--> peptide release--> leads to an increase in central response to same or lesser input= central sensitization--> further increase in pain perception |
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Term
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Definition
| peptides released in dorsal horn and upregulation of receptors may spread activation to associated touch pathway--> allodynia (pain from light touch- stimulates in same area) |
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Term
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Definition
| suppressed consciousness but nociceptive input continues |
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Term
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Definition
| blocks nociceptive input via opiate receptros in brainstem and dorsal horn |
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Term
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Definition
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Term
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Definition
| blocks prostaglandin produced |
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