Term
Most common intracranial adult tumor? |
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Definition
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What is the most common location for metastatic carcinomas of the brain? |
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Definition
axial location (grey/white junction) |
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Term
What does extra-axial brain tumor mean? |
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Definition
outside of the brain parenchyma |
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Term
What phakomotoses increases risk for meningioma's? |
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Definition
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common age for meningioma's? |
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Definition
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Term
Common sites for meningioma's? |
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Definition
parasagittal, sphenoid ridge, spinal cord |
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Term
Treatment for meningioma? |
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Definition
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Term
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Definition
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Growth characteristics of meningioma? |
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Definition
slow growing, benign, compresses brain, doesn't invade, well-circumscribed |
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Term
Cellular whorls of arachnoid cells are found in what tumor? |
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Definition
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Term
Bilateral schwannoma's indicate? |
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Definition
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Treatment for schwannoma? |
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Definition
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Term
Can schwannoma be removed without damaging nerve? |
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Definition
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Term
http://library.med.utah.edu/WebPath/CNSHTML/CNS187.html |
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Definition
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Term
Antoni A is described as? |
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Definition
cellular with palisading nuclei (schwannoma) |
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Term
Antoni B is described as? |
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Definition
loose, less cellular areas (schwannoma) |
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Term
What is a verocay body and is found in what tumor? |
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Definition
intervening anuclear zone between palisading nuclei |
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Term
Circumscribed astrocytoma's are found at what site and in what age group? |
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Definition
midline tumors found especially in cerebellum and optic nerve and found in children/young adults |
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Term
Diffuse astrocytoma's are what grades? |
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Definition
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Term
Circumscribed astrocytoma known as? |
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Definition
juvenile pilocytic astrocytoma |
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Term
This slow growing tumor has elongated spindle-shaped astrocytes, hyper and hypodense areas with microcysts, and like other slow growing tumors can have Rosenthal fibers? |
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Definition
Juvenile pilocytic astrocytoma |
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Term
What do astrocytoma's usually stain positive for? |
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Definition
GFAP (glial fibrillary acidic protein) |
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Term
Grade II astrocytoma's look similar to normal neuropil but as grade increases what happens? |
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Definition
astrocyte proliferation, vascular proliferation, necrosis |
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Term
Grade IV astrocytoma aka? |
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Definition
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Term
glioblastoma's are histologically described as? |
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Definition
highly cellular, pleomorphic, hyperplastic vascularity (glomeruloid looking vascular proliferation), mitoses, and necrosis |
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Term
Going from low grade astrocytoma to high grade there are cumulative gene abnormalities, two of these include? |
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Definition
p53 mutations and Loss of heterozygosity of c'some 10 |
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Term
what's the prognosis for glioblastomas? |
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Definition
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Term
What's the prognosis for low grade astrocytoma's |
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Definition
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Term
What type of response do diffuse astrocytoma's have to chemotherapy? |
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Definition
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Term
Site of oligodendrogliomas? |
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Definition
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Term
This tumor is poorly circumscribed, infiltrative, hemorrhagic, and has focal calcification in the cerebral hemispheres with a prognosis of 5 year survival? |
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Definition
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Term
fried egg appearance with perinuclear halo appearance and calcifications are seen in this tumor? |
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Definition
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Term
Chicken-wire vascular pattern, identified with factor VIII ab seen in this tumor type? |
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Definition
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Term
oligodendroglial tumors go through similar changes as what other tumor type to become malignant? |
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Definition
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Term
Treatment for oligodendroglial tumor? |
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Definition
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Term
Supratentorial ependymoma's found in what age group? |
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Definition
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Term
Common presentation for ependymoma? |
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Definition
symptoms of CSF obstruction |
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Term
Common site for ependymoma's? |
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Definition
4th ventricle and spinal cord |
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Term
These tumors are granular and flake off easily which enables them to seed this area? |
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Definition
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Term
Perivascular pseudorosettes are key diagnostic features of this tumor? |
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Definition
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Term
medulloblastoma's affect this patient population |
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Definition
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Term
In younger patients medulloblastomas are typically found here in young? here in old? |
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Definition
cerebellar vermis, lateral hemisphere of cerebellum |
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Term
Medulloblastoma's can seed this area? |
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Definition
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Term
Small, round blue cell tumor in cerebellum? |
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Definition
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Term
Rosette formation (blue cell tumor on pink neuropil fibrillary background) in this tumor? |
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Definition
medulloblastoma (other rosette's found in PNET) |
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Term
This can be found next to a variety of slow growing tumors? |
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Definition
Rosenthal fibers (pink beaded arrangement of astrocytic glial filaments) |
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Term
http://img.medscape.com/fullsize/migrated/439/170/nf439170.fig2.jpg |
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Definition
juvenile pilocytic astrocytoma (circumscribed astrocytoma) |
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Term
http://upload.wikimedia.org/wikipedia/commons/f/ff/Glioblastoma_(1).jpg |
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Definition
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Term
http://www.ajronline.org/content/vol181/issue1/images/large/07_AC1286_01E_color.jpeg |
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Definition
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Term
Tumor with chicken-wire vascular pattern? |
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Definition
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Term
Tumor you think of when there are Perivascular Pseudorosettes? |
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Definition
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Term
Homer Wright type rosettes? |
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Definition
Medulloblastoma with blue cells |
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Term
http://moon.ouhsc.edu/kfung/IACP-OLP/APAQ-Images/N1-TU-01-17.gif |
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Definition
rosettes seen in medulloblastoma |
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