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Neuro test #2
NOVA
82
Medical
Graduate
01/31/2011

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Cards

Term
what type of aphasia is the inability to repeat what he hears?
Definition
Wernicke's aphasia
Term
what tytype of aphasia is the inability to repeat what is said?
Definition
Broca's
Term
what is life-threatening condition is global aphasia associated with?
Definition
usually correlates with infarction of the middle cerebral artery
OR early manifestation of neoplastic, inflammatory, or degenerative disorder
Term
what is a lesion to the frontal lobe result in?
Definition
Broca's aphasia
Term
what does a lesion to the posterior temporal region result in?
Definition
Wernicke's aphasia
Term
what speech problem is caused by a stroke or CN involvement?
Definition
Dysarthria
Term
what is the treatment for Alcohol withdrawl?
Definition
Diazepam 5-20 mg po q4h prn
Term
Pt. presents with Paresthesias, + trousseau's, + chvostek....what is this? How do you treat?
Definition
Hypocalcemia
- tx: IV calcium gluconate and seizure precaution
Term
what is the most common cause of Meningitis? MC pathogen?
Definition
Viral Meningitis
MC pathogen: Enterovirus
Term
What are the tests used to diagnose meningitis?
Definition
1. Kernig's
2. Brudzinski
3. Lumbar puncture (cloudy CSF, high protein)
Term
How do you treat viral meningitis?
Definition
Acyclovir 1.25 mg/kg/day IV divided TID x10days
Term
what is an infection of the brain parenchyma?
Definition
Encephalitis
Term
what is characterized by hemiparesis, personality changes, focal seizure, ataxia, dysphagia, and hemiparesis?
Definition
encephalitis
Term
What is the most common cause of fatal encephalitis in the US?
Definition
Herpes Virus
Term
what is the second most common cause of dementia?
Definition
Dementia with Lewey Bodies
Term
what is the third most common cause of dementia?
Definition
Vascular (Multi-infart) dementia
Term
what should you screen for if you suspect dementia?
Definition
Depression
Term
what is a sudden,rapid, twitch like muscle contraction? how do you treat?
Definition
Myoclonus
- valproic acid (anticonvulsant)
-clonazepam (benzodiazepines_
Term
What is a form of myoclonus associated with hepatic encephalopathy?
Definition
Asterixis
Term
what does a CT or MRI demonstrate in patients with Huntington's?
Definition
atrophy of cerebral cortex and caudate nucleus
Term
what is Gilles de la Tourrette's syndrome?
Definition
chronic motor and vocal tics
Term
what drugs cause "tardive dyskinesia"
Definition
1. reglan
2. phenergan
3. haldol
Term
what are the "TRAP" presenting symptoms of parkinson's
Definition
1. Tremor (resting)
2. Rigidity
3. Akinesia/bradykinesia
4. Postural instability
Term
how do you test bradykinesia?
Definition
ask patient to "polish" the back of one hand with another, or tap the table with fingers of one hand then another
you will see "masked facies"
-characteristic of parkinson's
Term
what occurs when the function of both cerebral hemisphere or the brainstem RAS is compromised?
Definition
Loss of Consciousness
Term
what are two major causes of LOC?
Definition
1. seizure
2. syncope
Term
what is an episode of altered consciousness characterized by excessive or over-synchronized discharges of cerebral neurons?
Definition
Seizure
Term
what is characterized by brief symptoms that may precede the onset of some seizures?
Definition
aura
Term
what is sx is suggestive of a seizure vs. syncope?
Definition
syncope --> prodromal lightheadedness
seizure --> "aura" symptoms. postictal confusion state
Term
what labs do you order to confirm seizures? what may confirm seizures
Definition
glucose, calcium, FTA-ABS, electrolytes, CBC,ESR,BUN, Cr, LFTs
-EEG may confirm seizures but does not rule out if negative
Term
what is necessary to order with a patient presenting with a first time seizure?
Definition
emergent non-contrast CT
Term
when is an EEG indicated with seizures?
Definition
in a patient with new-onset generalized tonic-clonic seizures
Term
when is a lumbar puncture indicated with a seizing patient? when would you do a lumbar puncture?
Definition
Perform a lumbar puncture only after CT and MRI have demonstrated the ABSENCE of a intracranial lesion
Term
what is epilepsy?
Definition
a condition when a patient has RECURRENT seizures and may be essential (idiopathic) or due to secondary cause
Term
what is a partial seizure VS. generalized seizure?
Definition
Partial seizure - preservation of consciousness
Generalized - loss of consciousness
Term
Pt presents with abnormal unilateral movements, tachycardia, dysphagia, without LOC that last for less than 1 min...what type of seizure is this?
Definition
partial seizure (because no LOC)
Term
Pt has unilateral movements, involuntary movement (clapping hands, licking lips) and has altered consciousness. What type of seizure is this?
Definition
Complex partial seizure ( no LOC but amnesia for the event)
Term
what area of the brain is involved in complex partial seizures?
Definition
medial temporal or inferior frontal lobes
Term
what seizure is characterized by brief lapses of consciousness without a loss of postural control and a vacant stare?
Definition
Absence seizure
Term
What is the gold standard for diagnosing seizure disorders?
Definition
video EEG monitoring
Term
what is the physiologic effect of a seizure last less than 15 min?
Definition
tachycardia, elevated BP, hyperglycemia, elevated temp, leukocytosis
Term
what is the physiologic effect of a seizure lasting 15-30 min
Definition
hypotension, hypoglycemia, dysrhythmias, pulmonary edema
Term
What is the physiologic effect of a seizure lasting longer than 1 hour?
Definition
hypotension with decreased cerebral blood flow, disruption of BBB leading to cerebral edema
Term
what is the treatment of choice for generalized tonic clonic seizures?
Definition
Valproic Acid
Term
what type of seizure involve clonic movements of a single muscle group in face, limb or pharynx, often preceded by an aura? consciousness is preserved
Definition
partial seizure
Term
what type of seizure involves impaired consciousness, responsiveness, and memory with olfactory hallucinations?
Definition
Complex Partial seizures
Term
what is the most common type of seizure?
Definition
partial seizures (6/10 people with epilepsy)
Term
what is first line treatment for partial seizures?
Definition
Phenytoin 100 mg po TID
Term
7 y/o boy with hx of brief loss of consciousness for 5-10 seconds that accompanies blinking and head turnig...what are you thinking?
Definition
Absence seizure
Term
what type of seizure is a medical emergency? what does indicate?
Definition
Status epilepticus
- may indicate brain injury or death
(mortality rate is 20% for first episode)
Term
what Rx is consider for status epilepticus?
Definition
Thiamine 100 mg (pt. with hx of alcohol)
Diazepam 0.1-0.2 mg/kg IV
Lorazepam 0.1
Phenytoin 20 mg/kg IV with ECG monitor
Term
what is the time period for which seizures should be controlled?
Definition
30-40 mins
Term
what is the most common seizure trigger?
Definition
missing a dose of medication
Term
what is the temp of a febrile seizure?
Definition
>102 degree F
Term
what are Cheynes-Strokes respirations?
Definition
waxing and waning hyperpnea with brief eisodes of apnea seen in coma or stupor patients
Term
what two responses should be tested in an unconscious patient?
Definition
1. oculocephalic (doll's eyes) response
2. caloric response
Term
what is the management for a stupor or comatose patient?
Definition
1. ABCs
2. Intubation if GGS<8
3. IV NS with 25g dextrose, 100 mg thiamine, 0.4-1.2mg naloxone
Term
what are the cardinal features of brain death?
Definition
1. coma/unresponsiveness
2. absence of brainstem reflexes (fixed pupils, oculocephalic, gag, grimacing)
3. apnea ( no respiration even with PC02>60mmHg
Term
What are brain attack sx?
Definition
-trouble walking
-weakness on one side
-trouble seeing
-trouble speaking
Term
what is the most common type of stroke?
Definition
Ischemic Thrombotic
Term
what is the main risk factor for stroke?
Definition
arterial hypertension
Term
abrupt onset of symptoms followed by gradual improvement is suggest of what?
Definition
embolus
Term
abrupt onset with progression to maximal deficit over minutes to hours is suggesting of what?
Definition
thrombus
Term
onset during sleep or a stepwise progression is suggestive of what?
Definition
thrombus
Term
onset associated with severe headache or alterations in consciousness suggests?
Definition
intracerebral bleed
Term
what are the two classification of vascular supply to the brain?
Definition
1. anterior circulation
2. posterior circulation
Term
Patient present with abrupt onset of monocular blindness, transient aphasia, horner's sign , and carotid bruits. Where is the location of the occluded artery?
Definition
Carotid Artery Occlusion (anterior circulation stroke)
Term
patient present with sudden onset of contralateral paralysis that is affecting his leg more than his arm. He is apraxic and has abulia. Where is the occulsion causing these symptoms?
Definition
Anterior cerebral artery occlusion (anterior circulation stroke)
Term
Patient presents with hemiparesis that is affected his arm more than his leg. He has symptoms of global aphasia and homonymous hemianopsia. Where is the occlusion causing these symptoms?
Definition
Middle Cerebral Artery territory (anterior circulation stroke)
Term
What two occlusions are involved in posterior cerebral artery circulation?
Definition
1. posterior cerebral artery occlusion
2. vertebral basilar artery occlusion
Term
Pt presents with sudden hemianopsia, alexia without agraphy, sensory loss, athetosis (weird movement), Weber syndrome, and paralysis of the eye. What type of occlusion would cause this
Definition
Posterior Cerebral artery occlusion syndrome
Term
Patient presents with sudden onset of binocular visual disturbances, vertigo, drop attacks. What type of occlusion causes these symptoms?
Definition
Vertebral-Basilar Artery occlusion
Term
Patient present with presyncope, neuro deficits, and blood pressure differences between arms. What causes these symptoms?
Definition
Subclavian steal syndrome
Term
What disease causes slowly evolving symptoms of pure motor hemiplegia, dysarthria, ataxic hemiparesis, dementia?
Definition
Small vessel disease
Term
what type of imaging should you order for a suspected stroke?
Definition
STAT head CT!
Term
what are the 3 most prominent examination findings for acute stroke?
Definition
1. asymmetrical facial weakness
2. arm drift/weakness
3. abnormal speech (dysarthria)
Term
what is the most important diagnostic test when assessing a stroke patient?
Definition
non-contrast CT
Term
What does an ischemic stroke look like on noncontrast CT?
Definition
looks DARK (may look normal the first 24 hours)
Term
what does an Hemorrhagic stroke look like on noncontrast CT?
Definition
appears WHITE (seen earlier than ischemic)
Term
when should TPA be administed?
Definition
within the first 3 hours of the event
Term
when should IV TPA be administered?
Definition
administer in less than 60 mins after evaluation by a physician, and CT scan
Term
Subarachnoid Hemorrhage is suspected after a Nonconstrast CT is negative, what should you do next? what will you see?
Definition
Lumbar puncture
- Xanthochromia (yellow CSF) within 4 hours from time of hemorrhage
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