Term
what type of aphasia is the inability to repeat what he hears? |
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Definition
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Term
what tytype of aphasia is the inability to repeat what is said? |
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Definition
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Term
what is life-threatening condition is global aphasia associated with? |
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Definition
usually correlates with infarction of the middle cerebral artery OR early manifestation of neoplastic, inflammatory, or degenerative disorder |
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Term
what is a lesion to the frontal lobe result in? |
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Definition
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Term
what does a lesion to the posterior temporal region result in? |
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Definition
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Term
what speech problem is caused by a stroke or CN involvement? |
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Definition
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Term
what is the treatment for Alcohol withdrawl? |
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Definition
Diazepam 5-20 mg po q4h prn |
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Term
Pt. presents with Paresthesias, + trousseau's, + chvostek....what is this? How do you treat? |
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Definition
Hypocalcemia - tx: IV calcium gluconate and seizure precaution |
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Term
what is the most common cause of Meningitis? MC pathogen? |
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Definition
Viral Meningitis MC pathogen: Enterovirus |
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Term
What are the tests used to diagnose meningitis? |
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Definition
1. Kernig's 2. Brudzinski 3. Lumbar puncture (cloudy CSF, high protein) |
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Term
How do you treat viral meningitis? |
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Definition
Acyclovir 1.25 mg/kg/day IV divided TID x10days |
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Term
what is an infection of the brain parenchyma? |
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Definition
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Term
what is characterized by hemiparesis, personality changes, focal seizure, ataxia, dysphagia, and hemiparesis? |
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Definition
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Term
What is the most common cause of fatal encephalitis in the US? |
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Definition
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Term
what is the second most common cause of dementia? |
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Definition
Dementia with Lewey Bodies |
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Term
what is the third most common cause of dementia? |
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Definition
Vascular (Multi-infart) dementia |
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Term
what should you screen for if you suspect dementia? |
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Definition
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Term
what is a sudden,rapid, twitch like muscle contraction? how do you treat? |
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Definition
Myoclonus - valproic acid (anticonvulsant) -clonazepam (benzodiazepines_ |
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Term
What is a form of myoclonus associated with hepatic encephalopathy? |
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Definition
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Term
what does a CT or MRI demonstrate in patients with Huntington's? |
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Definition
atrophy of cerebral cortex and caudate nucleus |
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Term
what is Gilles de la Tourrette's syndrome? |
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Definition
chronic motor and vocal tics |
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Term
what drugs cause "tardive dyskinesia" |
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Definition
1. reglan 2. phenergan 3. haldol |
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Term
what are the "TRAP" presenting symptoms of parkinson's |
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Definition
1. Tremor (resting) 2. Rigidity 3. Akinesia/bradykinesia 4. Postural instability |
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Term
how do you test bradykinesia? |
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Definition
ask patient to "polish" the back of one hand with another, or tap the table with fingers of one hand then another you will see "masked facies" -characteristic of parkinson's |
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Term
what occurs when the function of both cerebral hemisphere or the brainstem RAS is compromised? |
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Definition
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Term
what are two major causes of LOC? |
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Definition
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Term
what is an episode of altered consciousness characterized by excessive or over-synchronized discharges of cerebral neurons? |
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Definition
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Term
what is characterized by brief symptoms that may precede the onset of some seizures? |
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Definition
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Term
what is sx is suggestive of a seizure vs. syncope? |
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Definition
syncope --> prodromal lightheadedness seizure --> "aura" symptoms. postictal confusion state |
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Term
what labs do you order to confirm seizures? what may confirm seizures |
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Definition
glucose, calcium, FTA-ABS, electrolytes, CBC,ESR,BUN, Cr, LFTs -EEG may confirm seizures but does not rule out if negative |
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Term
what is necessary to order with a patient presenting with a first time seizure? |
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Definition
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Term
when is an EEG indicated with seizures? |
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Definition
in a patient with new-onset generalized tonic-clonic seizures |
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Term
when is a lumbar puncture indicated with a seizing patient? when would you do a lumbar puncture? |
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Definition
Perform a lumbar puncture only after CT and MRI have demonstrated the ABSENCE of a intracranial lesion |
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Term
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Definition
a condition when a patient has RECURRENT seizures and may be essential (idiopathic) or due to secondary cause |
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Term
what is a partial seizure VS. generalized seizure? |
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Definition
Partial seizure - preservation of consciousness Generalized - loss of consciousness |
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Term
Pt presents with abnormal unilateral movements, tachycardia, dysphagia, without LOC that last for less than 1 min...what type of seizure is this? |
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Definition
partial seizure (because no LOC) |
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Term
Pt has unilateral movements, involuntary movement (clapping hands, licking lips) and has altered consciousness. What type of seizure is this? |
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Definition
Complex partial seizure ( no LOC but amnesia for the event) |
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Term
what area of the brain is involved in complex partial seizures? |
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Definition
medial temporal or inferior frontal lobes |
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Term
what seizure is characterized by brief lapses of consciousness without a loss of postural control and a vacant stare? |
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Definition
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Term
What is the gold standard for diagnosing seizure disorders? |
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Definition
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Term
what is the physiologic effect of a seizure last less than 15 min? |
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Definition
tachycardia, elevated BP, hyperglycemia, elevated temp, leukocytosis |
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Term
what is the physiologic effect of a seizure lasting 15-30 min |
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Definition
hypotension, hypoglycemia, dysrhythmias, pulmonary edema |
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Term
What is the physiologic effect of a seizure lasting longer than 1 hour? |
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Definition
hypotension with decreased cerebral blood flow, disruption of BBB leading to cerebral edema |
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Term
what is the treatment of choice for generalized tonic clonic seizures? |
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Definition
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Term
what type of seizure involve clonic movements of a single muscle group in face, limb or pharynx, often preceded by an aura? consciousness is preserved |
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Definition
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Term
what type of seizure involves impaired consciousness, responsiveness, and memory with olfactory hallucinations? |
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Definition
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Term
what is the most common type of seizure? |
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Definition
partial seizures (6/10 people with epilepsy) |
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Term
what is first line treatment for partial seizures? |
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Definition
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Term
7 y/o boy with hx of brief loss of consciousness for 5-10 seconds that accompanies blinking and head turnig...what are you thinking? |
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Definition
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Term
what type of seizure is a medical emergency? what does indicate? |
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Definition
Status epilepticus - may indicate brain injury or death (mortality rate is 20% for first episode) |
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Term
what Rx is consider for status epilepticus? |
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Definition
Thiamine 100 mg (pt. with hx of alcohol) Diazepam 0.1-0.2 mg/kg IV Lorazepam 0.1 Phenytoin 20 mg/kg IV with ECG monitor |
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Term
what is the time period for which seizures should be controlled? |
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Definition
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Term
what is the most common seizure trigger? |
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Definition
missing a dose of medication |
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Term
what is the temp of a febrile seizure? |
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Definition
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Term
what are Cheynes-Strokes respirations? |
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Definition
waxing and waning hyperpnea with brief eisodes of apnea seen in coma or stupor patients |
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Term
what two responses should be tested in an unconscious patient? |
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Definition
1. oculocephalic (doll's eyes) response 2. caloric response |
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Term
what is the management for a stupor or comatose patient? |
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Definition
1. ABCs 2. Intubation if GGS<8 3. IV NS with 25g dextrose, 100 mg thiamine, 0.4-1.2mg naloxone |
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Term
what are the cardinal features of brain death? |
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Definition
1. coma/unresponsiveness 2. absence of brainstem reflexes (fixed pupils, oculocephalic, gag, grimacing) 3. apnea ( no respiration even with PC02>60mmHg |
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Term
What are brain attack sx? |
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Definition
-trouble walking -weakness on one side -trouble seeing -trouble speaking |
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Term
what is the most common type of stroke? |
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Definition
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Term
what is the main risk factor for stroke? |
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Definition
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Term
abrupt onset of symptoms followed by gradual improvement is suggest of what? |
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Definition
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Term
abrupt onset with progression to maximal deficit over minutes to hours is suggesting of what? |
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Definition
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Term
onset during sleep or a stepwise progression is suggestive of what? |
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Definition
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Term
onset associated with severe headache or alterations in consciousness suggests? |
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Definition
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Term
what are the two classification of vascular supply to the brain? |
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Definition
1. anterior circulation 2. posterior circulation |
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Term
Patient present with abrupt onset of monocular blindness, transient aphasia, horner's sign , and carotid bruits. Where is the location of the occluded artery? |
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Definition
Carotid Artery Occlusion (anterior circulation stroke) |
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Term
patient present with sudden onset of contralateral paralysis that is affecting his leg more than his arm. He is apraxic and has abulia. Where is the occulsion causing these symptoms? |
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Definition
Anterior cerebral artery occlusion (anterior circulation stroke) |
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Term
Patient presents with hemiparesis that is affected his arm more than his leg. He has symptoms of global aphasia and homonymous hemianopsia. Where is the occlusion causing these symptoms? |
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Definition
Middle Cerebral Artery territory (anterior circulation stroke) |
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Term
What two occlusions are involved in posterior cerebral artery circulation? |
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Definition
1. posterior cerebral artery occlusion 2. vertebral basilar artery occlusion |
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Term
Pt presents with sudden hemianopsia, alexia without agraphy, sensory loss, athetosis (weird movement), Weber syndrome, and paralysis of the eye. What type of occlusion would cause this |
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Definition
Posterior Cerebral artery occlusion syndrome |
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Term
Patient presents with sudden onset of binocular visual disturbances, vertigo, drop attacks. What type of occlusion causes these symptoms? |
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Definition
Vertebral-Basilar Artery occlusion |
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Term
Patient present with presyncope, neuro deficits, and blood pressure differences between arms. What causes these symptoms? |
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Definition
Subclavian steal syndrome |
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Term
What disease causes slowly evolving symptoms of pure motor hemiplegia, dysarthria, ataxic hemiparesis, dementia? |
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Definition
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Term
what type of imaging should you order for a suspected stroke? |
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Definition
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Term
what are the 3 most prominent examination findings for acute stroke? |
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Definition
1. asymmetrical facial weakness 2. arm drift/weakness 3. abnormal speech (dysarthria) |
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Term
what is the most important diagnostic test when assessing a stroke patient? |
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Definition
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Term
What does an ischemic stroke look like on noncontrast CT? |
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Definition
looks DARK (may look normal the first 24 hours) |
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Term
what does an Hemorrhagic stroke look like on noncontrast CT? |
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Definition
appears WHITE (seen earlier than ischemic) |
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Term
when should TPA be administed? |
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Definition
within the first 3 hours of the event |
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Term
when should IV TPA be administered? |
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Definition
administer in less than 60 mins after evaluation by a physician, and CT scan |
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Term
Subarachnoid Hemorrhage is suspected after a Nonconstrast CT is negative, what should you do next? what will you see? |
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Definition
Lumbar puncture - Xanthochromia (yellow CSF) within 4 hours from time of hemorrhage |
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