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Neuro Seminar
Neuro Seminar Final
53
Other
Professional
04/06/2010

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Term
Neuropraxia
Definition
Conduction block. conduction speeds in nerve segments above/below theinvolved segment are normal since axon is not damaged.
Term
What are the two ways to get neuropraxia?
Definition
By ischemia, or demyelination.
Term
Axonometsis
Definition
Class II injury. Usually a crush injury. Wallerian degeneration distal to the lesion. The connective tissue/Schwann cells are intact. Nerve regrowth 1mm/day.
Term
Neurotmesis
Definition
class III injury. knife cut or stretch. The connective tissue is injured and reinnervation may be incomplete. A nerve cut requires surgical repair and a neuroma may form.
Term
Polyneuropathy
Definition
Usually not focal (generalized) & symmetric. Usually caused by toxicity, metabolic problem, or autoimmune. Usually starts distally.
Term
Example of axonopathy
Definition
Diabetes
Term
Example of Myelinopathy
Definition
Guillan-Barre Syndrome
Term
Neuronopathy
Definition
ALS,Herpes Zoster
Term
Paresis
Definition
Refers to partial paralysis
Term
Paralysis
Definition
refers to complete inability to move a limb.
Term
Bell's Palsy
Definition
compression of CN VII
Term
Poliomyelitis
Definition
An infection of the LMN. Results in LMN death and eventually paresis.
Term
Coupe contre Coupe
Definition
occurs in a rear end car wreck when the brain inertia prevents it from moving. Brain moves to back of skull then forward.
Term
Can a linear fracture occur without brain injury?
Definition
Yes
Term
Cominuted fracture
Definition
shattering of bone into pieces.
Term
Compoud fracture
Definition
depressed fracture with scalp lacerations, creating communication path in intracranial cavity.
Term
Basal Fracture
Definition
involves base of skull, especially frontal bone and temporal bone. May cause CSF leak. Possible injury to internal carotied artery.
Term
Contusion
Definition
can initiate processes of secondary damage. A bruise
Term
Epi-dural hematoma
Definition
associated with skull fracture involving middle meningeal artery. Momentary unconscious, lucid for several hours, rapid deteriorating conciousness.
Term
Sub-dural hematoma
Definition
blood betwen dura and arachnoid. immediate pressure on brain. Acute- major trauma from contusion/laceration; headache, drowsy, agitated, worsening confusion.
Term
Cranial nerve damaged with anterior cranial fossa fx.
Definition
Olfactory & optic nerves.
Term
Temporal Bone fx.
Definition
facial & auditory nerves.
Term
Orbital plate fx.
Definition
optic & occulomotor nerves.
Term
What cranial nerve is damaged with a cribiform plate fx?
Definition
olfactory nerve.
Term
hydrocephalus
Definition
Normal flow of CSF is obstructed and pressure builds in the skull. Decerebrate posturing, papillary dilation, respiratory arrest.
Term
What is possible secondary damage to the brain following a TBI?
Definition
elevated intra-cranial pressure.
Term
Coma
Definition
lack of responsiveness even to painful stimuli; no sleep/wake cycles; usually doesn't last longer than 2 weeks.
Term
Persistent Vegetative State
Definition
vegetative state > 3 months
Term
Stupor
Definition
condition of general unresponsiveness; can sometimes be aroused by vigorous stiulation
Term
Obtundity
Definition
Pt. sleeps a lot; when aroused has reduced alertness and is not interested in the environment.
Term
Delirium
Definition
Misrepresentation of sensory stimuli; disorientation, fear, and agitation
Term
Clouding of consciousness
Definition
quiet confusion, distractable, slow resonse time, faulty memory
Term
Concussion
Definition
brief period of lost consciousness after injury; no apparent deficts
Term
What are the clinical symptoms of a tumor?
Definition
Headaches, aggravated by abrupt increases in ICP: coughing, sneezing, straining. Nausea, vomiting, seizures. symptoms depend on the location of the tumor.
Term
Astrocytoma
Definition
most common, types of cells: astrocytes:
Term
Glioblastoma Multiforme
Definition
GBM, Malignant astrocytoma, Necrosis inside the tumor, less than 15% 2 year survival
Term
Oligodendroma
Definition
cancer of the oligodendrocytes. frontal lobe which controls concentration. less common; slow growing. eventually recur.
Term
Ependymoma
Definition
These cells are what line the insides of the ventricles. If the tumor occurs in the fourth ventricle then will affect the function of the cerebellum and the brain stem.
Term
Medulloblastoma
Definition
origininates in the cerebellum or posterior fossa. grow very rapidly and spread via the CSF
Term
Mass Effect
Definition
Size/volume of tumor. This causes pressure, shifting and hernation.
Term
Subfalcine Herniation
Definition
When the portion of cortex on the side of the mid saggital sulcus crosses over due to pressure
Term
Uncal Herniation
Definition
When part of the cortex herniates into the midbrain/cerebellum area. Dilated, unresponsive pupil (CNIII) hemiplegia, coma.
Term
Central (transtentorial) herniation
Definition
midbrain and pons through the tentorium cerebelli. Symptoms: CNIV tension, Coma.
Term
Tonsilar Herniation
Definition
Cerebellum migrates into the foramen magnum. Symptoms: respiratory arrest BP instability. Death.
Term
Disorders of Neurons
Definition
CNS neuronal cell death. regeneration. peripheral nerve injury.
Term
Bechterew's Sign stimulus and response
Definition
Stimulus - alternate volitional flexion & extension of the forearms. Response - inability to smoothly extend elbow; slow, jerky alterations.
Term
Clonus
Definition
Stimulus - rapidly extend the wrist or ankle. Response - rapid reciprocal flexion/extension.
Term
Forced grasping
Definition
Stimulus - stroke the palm in a radial direction. Response - grasping motion.
Term
Babinski's sign
Definition
Stimulus - stroke the outer edge of sole of the foot. Response - great toe extension; other toes flex and abduct.
Term
Huntington's Sign
Definition
Stimulus - cough, sneeze, GI strain, yawn. Response - UE elbow flexion, wrist flexion, glenohumeral adduction; LE hip/knee flexion.
Term
Cremasteric
Definition
Stimulus - stroke medial surface fo upper thigh, usually toward the groin. Response - testicular elevation on the same side being tested.
Term
Superficial Anal
Definition
Stimulus - prick/touch perineum. Response - Anal sphincter constricts.
Term
Bulbocavernosus
Definition
Stimulus - pinching dorsum of glans of the penis; gentle pull on the catheter. Response - Anal sphincter constricts; contraction of bulbous urethra.
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