Shared Flashcard Set

Details

Neuro/Psych-ICM
CNS Infections
20
Microbiology
Graduate
01/04/2011

Additional Microbiology Flashcards

 


 

Cards

Term
What is the symptom that must be present to assume encephalitis
Definition
Mental status changes
Term
What are the the most common organisms for children <2, 2-18 yr olds, and 19-59 yr olds?
Definition

Children <2: GBS

2-18yr olds: Nesseria Meningitidis

19-59 yr olds: Strep Pneumo

Term
What organism is the most common cause of bacterial meningitis?
Definition
S. pneumoniae
Term
What populations are typuically affected by listeria monocytogenes
Definition

Neonates, Elderly, or Immunosurpressed

Systemic Diseases or Organ Failure

(Diabetes, Malignancy, Alcoholism, Hepatic/Renal Disease, Collagen-Vascular)

Term
What is the difference in the presentation of early vs late-onset GBS Meningitis
Definition

Early onset usuall presents with septicemia, respiratory distress, and meningitis in premature babies

Late onset presents like classic meningitis

Term
What is the major risk factor for recurrent Nesseria meningitidis meningitis?
Definition
Terminal Complement Deficiencies
Term
What are the most common causes of bacterial meningitis
Definition

Streptococcus pneumoniae

Nesseria Meningitidis

Group B Strep

Listeria Monocytogenes

Haemophilus Influenzae

Term
Which of the common bacteria meningitis agents presents with concurrent focal infections(pneumonia, Otitis media)
Definition
Strep Pneumo and H. Flue
Term
What are the common bacteria organisms that cause meningitis after a neurosurgical procedure?
Definition

Gram Negative Aerobes

Staphylococci

Term
What is the typical presentation of Bacterial meningitis
Definition

Fever, headache, stiff neck

Progression to Loss of consciousness and confusion

Term
What are the symtoms and major signs of bacterial meningitis
Definition

Fever

Meningismus

Kernig's Sign: flex head in supine-Flexing knee and hip is positive

Brudzinski's sign: Supine position with flexed knee and hip and try to involuntarily extend both-Positive is resistance

Term
What is the typical appearance of CSF fluid in bacterial meningitis and how does viral meningitis differ?
Definition

Cloudy

Low Glucose

High Protein

WBCs mostly PMNs

High Pressure

Viral: WBCs mostly lymphocytes,Normal glucose, less pressure

 

Term
What is the typical analysis when bacterial meningitis is suspected
Definition

CSF: Glucose, Protein, Pressure, Culture, Gram stain, WBC

Blood Culture

Radiologic

Bacteria Antigen Test only if gram stain is negative and patient is on Anti-biotics

Term
How is the manifestation of viral meningitis different than bacterial meningitis?
Definition
Viral has a slower onset with milder intensity
Term
What are the major causes of viral meningitis/encephalitis and which will show more severe alteration in consciousness
Definition

Enteroviruses

Arboviruses

HSV type I: Mainly causes encephalitis; most severe.

Term
In what type of presentation should you suspect cryptococcus meningitis
Definition
Insidious onset of headache and fever in an immunosupressed patient(typically AIDS)
Term
What testing usually needed to make a diagnosis of tuberculous meningitis
Definition
Serial LP
Term
What are the common causes of Chemical meningitis?
Definition

Trimethoprim/ Sulfamethoxazole

Spinal Anesthesia

Myelogram

NSAIDS

Term
When should a LP be withheld until after head imaging
Definition
If a focal lesion is suspected in the brain
Term
What drugs are used as empiric therapy for bacterial meningitis and why?
Definition

3rd Gen Cephalosporin: For the common bugs

Vancomycin: For Strep pneumo resistance

Ampicillin: If young, old or immunosuppressed(listeria)

Dexamethasone: Reduce inflammation and scarring of the meninges

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