Term
| What percent of patients with mild cognitive impairment convert to dementia in 1 year |
|
Definition
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|
Term
| What are the imaging indications of MCI? |
|
Definition
| Only able to see slight temporal atrophy |
|
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Term
|
Definition
| Blind, but lack insight about their blindness |
|
|
Term
| Where is the lesion in alexia w/o agraphia and Left Hemineglect |
|
Definition
Alexia w/o Agraphia: Left Occipital
Left Hemineglect: Right Parietal |
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Term
| What should a patient be evaluated for if a patient believes they are impaired, but testing seems normal? |
|
Definition
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|
Term
| What are some common causes of delerium |
|
Definition
New Meds
Infection
Metabolic problems |
|
|
Term
|
Definition
Ongoing
Memory loss
Multiple cognitive areas are effected
Decline from Base Line
Impairs patients functioning |
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Term
| What are the imaging studies help to identify Alzheimer's |
|
Definition
MRI: Hippocampal and Parahippocampal gyrus atrophy
SPECT/PECT: Biparietal Hypometabolism |
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Term
| Genes associated with Early-onset Autosomal Dominant Alzheimer's |
|
Definition
Presilin 1 and 2
Amyloid Precusor Protein
ApoE-E4 allele
E2 allele is protective against Alzheimers |
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Term
| Scale used to rate vascular dementia |
|
Definition
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Term
| What are the most common signs of Lewy Body dementia and what drug do these patients respond to? |
|
Definition
Parkinson's
Hallucinations/Delusions
Fluctuations in Disease
Drug: Acetylcholinesterases |
|
|
Term
| What genes are associated with Early-Onset Autosomal Dominant Frontotemporal Dementia |
|
Definition
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|
Term
| What are the effects of Progranulin overproduction and underproduction |
|
Definition
Overproduction: Cancer
Underproduction: Frontotemporal dementia |
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|
Term
| What are the signs of Creutzfeldt-Jacob disease and what studies are used to diagnose it? |
|
Definition
Rapidly Progressive Dementia
Myoclonus
Seizures
Some Visual Change and Ataxia
EEG
High Amplitude Discharges
MRI **(best diagnostic)**
Abnormal diffusion sequences
Basal Ganglia signal |
|
|
Term
| What are the signs of Normal Pressure Hydrocephalus and what studies aid in a diagnosis |
|
Definition
Magnetic Gait and Incontinence
MRI: Jet Sign-aqueduct and 3rd Ventricle flow void |
|
|
Term
| What aspects of the mini-mental are first positive signs of Alzheimer's |
|
Definition
Delayed Recall
then Orientation to time |
|
|
Term
| What are the aspects of the folstein's mini mental status exam |
|
Definition
Orientation(10): Time and Place
Memory(6): Delayed and Imeadiate
Language(5): Naming(2), Read, Write, Repitition
Attention/Calculation(5): Spelling Backward, Serial Sevens
Multistep Sequence(3): 3 Commands
Visual Spatial(1): Intersecting Pentagons |
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|
Term
| What is hippocampal amnesia? How is it different than Korsakoff's? |
|
Definition
Inability to form new memories
Korsakoff's has confabulation additionally |
|
|
Term
| What study should be done when a focal cognitive syndrome is indicated? |
|
Definition
|
|
Term
| What are the typical types of meds that can cause confusion in a patient |
|
Definition
Cardiac
Bladder
CNS Drugs |
|
|
Term
| What pathology is indicated by the abrupt onset of focal neurological symptoms? |
|
Definition
| Vascular Cognitive Impairment |
|
|
Term
| What are some risk factors for getting Cruetxfeldt-Jakob Disease? |
|
Definition
Corneal Transplant
Dural Graft
Growth Hormone Extract
Injesting Contaminated Beef |
|
|
Term
| What are the limitations to the Mini-Mental Status Exam |
|
Definition
Language Dependant
Low Sensitivity in High Functioners
Low Sensitivity to frontal lobe lesions |
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