Term
|
Definition
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|
Term
| what are examples of SSRIs -4 |
|
Definition
citalopram
fluoxetine
sertraline
paroxetine |
|
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Term
| what is the main severe side affect of SSRis |
|
Definition
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Term
| how is the effiacy of SSRis compared wiht MAOi and TCAs |
|
Definition
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Term
early action of SSRIs is
what does it do with chronic use |
|
Definition
incease 5 HT due to reuptake inhibit
alters gene expression and changes brain fucntion |
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Term
| SSRIs work well to relieve pts who are experieincing what? but they do not relieve symtpoms of decreased? |
|
Definition
negative affect (lonliness, irritable)
postive affect (self confidence, enthusiasm) |
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Term
|
Definition
| agitation, panic attacks, reslessness movements, myoclunus at night, inhibiton of ejaculaiton, GI porblems, |
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Term
| symtpoms of serotonin syndrome-4 |
|
Definition
tachycardia
HTN
tremors
diaphoresis |
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Term
| if you combine SSRIs with what med you get the most lethal chance for serotonin syndrome |
|
Definition
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Term
| what meddds cna cause serotonin snyndrome by themsevles-6 |
|
Definition
SSRis
MAOis
TCAs 5 HT selective (tertiary)
lithium salts
opiates
St john's wart hyperforin extract |
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|
Term
32% of ppl also experience what big side effect from SSRis?
why? |
|
Definition
hyponatremia
bc too much secretion of antiiduretic hormone (ADH) |
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Term
|
Definition
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|
Term
fluoxetine is an antagonist for what specific receptor?
what is the effect? |
|
Definition
5HT2C
increased Ne and DA (more energy) |
|
|
Term
| what is negtive side affect of the fluoxetine |
|
Definition
|
|
Term
| at high doses fluoxetine can also inhibit what-3 |
|
Definition
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|
Term
| what is the generic of zoloft |
|
Definition
|
|
Term
what 2 other recptors does sertraline block?
what do each of them cause |
|
Definition
sigma 1
DA reuptake
sigma 1= antianxiety
DA reuptake- slightly increase energy |
|
|
Term
| what is the generic for paxil |
|
Definition
|
|
Term
| what are paroxetine's effects from different receptors |
|
Definition
calming
weak NET inhibition= more efficacy
block NOS- sexual dysfunction |
|
|
Term
| what SSRI is known for having withdrawal rxns |
|
Definition
|
|
Term
| what drug is a potent inhibitor and subsstrate of 2D6 |
|
Definition
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|
Term
| what is the generic for Luvox |
|
Definition
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|
Term
what SSRI is more used for OCD and anxiety?
why? |
|
Definition
fluvoxemine
signma 1 agonist- axiolytic |
|
|
Term
| whcih drug interacts with 3A4 and 1A2? |
|
Definition
|
|
Term
| what is the generic for cipramil |
|
Definition
|
|
Term
| what enantiomer for citalopram is antagonist for SERT |
|
Definition
|
|
Term
| what are the 3 better things about escitalopram |
|
Definition
no anti H1
no 2D6 inhibition
pure SERt inhibitoin |
|
|
Term
|
Definition
|
|
Term
| what is the generic of effexor |
|
Definition
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|
Term
at low doses venalfaxine blocks?
what about hgih doses? |
|
Definition
|
|
Term
| what is venalfaxine also a substrate for? |
|
Definition
|
|
Term
| what are side effects of venalfaxine |
|
Definition
| sexual dysfunctoin and nausea |
|
|
Term
| what meds block both Na and DA reuptake-1 |
|
Definition
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|
Term
| what is the generic for wellbutrin |
|
Definition
|
|
Term
what drug has golilocks drug solution?
what is this? |
|
Definition
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|
Term
|
Definition
|
|
Term
| dluoxetine is also an inhibitor of? |
|
Definition
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|
Term
what is the atypicla antidepressant
WHAT is its main other functoin |
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Definition
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Term
|
Definition
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Term
|
Definition
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|
Term
mirtzapine also has strong ___ properties?
why? |
|
Definition
|
|
Term
| what is the med that can begin working in 1 week only |
|
Definition
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Term
|
Definition
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