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Neuro drugs part 3
lots of drugs
62
Medical
Graduate
11/08/2009

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Term
Morphine
Definition
opioid, agonizes mu receptors
Term
Haloperidol
Definition
Neuroleptic, anti-psychotic
Antagonizes post synaptic DA receptors
Term
Cholorpromazine
Definition
Neuroleptic, anti-psychotic
Antagonizes post synaptic DA receptors
Term
Diezapam/ valium
Definition
Benzodiazepine, seditive/hypnotic
positive allosteric modulator of GABA. Can be used for seizures. Can help panic disorders
Term
Phenobarbitol
Definition
Barbituate, seditive/hyptnoic
positive allosteric modulator of GABA.
1st generation anti-epileptic.
Term
Enflurane
Definition
gaseous general anesthetic
Term
Sumitriptan
Definition
Triptan. agonizes 5-HT.
migraines
Term
Theobromide
Definition
methyl-xanthine
antagonist of adenosine receptors
Term
Theophylline
Definition
methyl-xantine, antagonizes adenosine receptors, stimulant
Term
Methamphetamine
Definition
Amphetamine. agonist for trace amines. stimulant, good for ADHD
Term
Ketamine
Definition
dissociatve analgesiac. antagonizes NMDA receptors. Analgesia, hallucinations.
Term
Phencyclidine
Definition
dissociative analgesic. Antagonizes NMDA receptors
Term
Fluoxetine (Prozac)
Definition
SSRI, antidepressant
Term
Phenelyzine
Definition
MAOI, antidepressant
Term
Cocaine
Definition
blocks DA reuptake at terminal
Term
Bromocriptine
Definition
Anti-parkinsons, agonizes post synaptic DA receptors
Term
LSD
Definition
5-HT post synpatic receptor agonist
Term
Phenytoin
Definition
1st generation anti-epileptic. Rapidly titrated, gold standard for status epilepticus. Cosmetic side effects and hepatic enzyme inducer.
Term
Ethosuxamide
Definition
1st generation anti-epileptic. Treament for absence seizures. Acts on T type Ca channel
Term
Carbazepine
Definition
1st generation anti-epileptic. Gold standard for partial seizures. Must monitor liver function
Term
Valproate
Definition
1st generation anti-psychotic. Gold standard for generalized seizures.
Term
Felbemate
Definition
2nd generation anti-epileptic. Caused fatal agranulocytosis
Term
Gabapentine
Definition
2nd generation anti-epileptic, not super effective
Term
Lamitrigine
Definition
2nd generation anti-epileptic. Treats broad spectrum. Titrate carefully because can cause Steven-Johnson syndrome
Term
Oxycarbazepine
Definition
2nd generation anti-epileptic. Safer than Carbazepine, good efficacy.
Term
Levatiracetam (Kepra)
Definition
2nd generation anti-epilpetic. Treats broad spectrum. 10% get behavioral disturbance.
Term
Topiramate
Definition
anti-epileptic, also used as a prophylaxis for migraine and to prevent alcoholism relapse
Term
Migraine Prophylaxis
Definition
Antidepressants, beta blockers, Ca channel blockers, topiramate
Term
Naltrexone
Definition
opioid receptor antagonist, used to prevent alcoholics and opioid addicts from relapsing. side effects of dysphoria.
Term
Acamprosate
Definition
used to reduce long term withdrawl symptoms of alcoholism to prevent relapse
Term
disulfiram
Definition
blocks aldehyde dehydrogenase, causing really bad symptoms if you drink alcohol
Term
PCP
Definition
clocks NMDA associated ion channel. causes both negative and positive symptoms of schizophrenia
Term
Atypical antipsychotics
Definition
antagonize 5-HT receptors more than DA. This reduces extrapyrimadal side effects by increasing actication in nigrostriatal pathway.
Term
First generation anti-psychotics
Definition
DA antagonists, but cause extrapyridal symtoms bc also block nigrostriatal pathway
Term
Ecstacy
Definition
blocks 5-HT reuptake, hallucinogenic
Term
Tricyclics, first generation
Definition
SNRIs, good for depression and chronic painm lots of side effects
Term
Tricyclics, next generation
Definition
NRIs, good for depression and chornic pain, lots of side effects
Term
Amitriptaline
Definition
Tricyclic antidepressant
Term
Amoxapine
Definition
Tricyclic antidepressant
Term
Desipramine
Definition
Tricyclic antidepressant
Term
Doxiprine
Definition
Tricyclic antidepressant
Term
Imipramine
Definition
Tricyclic antidepressant
Term
Nortryptaline
Definition
Tricyclic antidepressant
Term
MAOIs
Definition
increase DA levels, and also some 5-HT and NE. must eat a tyromine free diet. good for depression and anxiety
Term
Tranylcypromine
Definition
MAOI
Term
Isocarboxide
Definition
MAOI
Term
SSRIs
Definition
increase 5-HT, and also some NE and DA
Term
Citalopram
Definition
SSRI
Term
Fluoxetine
Definition
SSRI
Term
Fluvoxamine
Definition
SSRI
Term
Paroxetine
Definition
SSRI
Term
Sertraline
Definition
SSRI
Term
Escitalopram
Definition
SSRI
Term
Second generation SNRIs
Definition
increases 5-HT and NE, good for anxiety, pain, biopolar as well as depression
Term
Venlafaxine
Definition
SNRI
Term
desvenylfaxine
Definition
SNRI
Term
Duloxetine
Definition
SNRI
Term
SARI
Definition
5-HT agonist and reuptake inhibitor.
Term
Mirtazapine
Definition
NaSS
Term
NaSS
Definition
NE specific 5-HT antidepressants. antagonize NE and 5-HT receptors, leading to greater NE and 5-HT release
Term
COMT inhibitors
Definition
given with l-dopa in parkinsons disease to furhter increase DA
Term
propranolol
Definition
a beta-blocker, useful for performance anxiety
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