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sensory input, integration, and control of body |
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composed of brain and spinal cord. control center for body. |
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(CNS) integrate info and controls responses medulla oblongata and hypothalamus |
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heart rate, blood pressure, co2 and respiration |
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body temp, heart rate, blood pressure |
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connects everything to CNS it is all nerve tissue not of the brain or spinal cord afferent and efferent cells |
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PNS cells that carry info to CNS from organs and skin |
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PNS carry info away from CNS motor neurons |
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part of the PNS connects CNS with skeletal muscles |
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connects CNS and smooth muscle, cardiac muscle and glands involuntary control of body and internal function works with endocrine system 2 parts: sympathetic and parasympathetic |
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fight or flight response relaxes intestinal wall, increases sweating and heart rate |
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resting and digesting contracts intestine, decreases sweating and heart rate |
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regeneration of neurons located int he hippocampus and olfactory bulb increased in low stress, exercise conditions |
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outnumber neurons 50:1 1/2 weight of brain smaller than neurons, protect them |
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astrocytes, oligodendrocytes, ependymal, microglia |
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most numerous presents antigens maintains K+, neurotransmitters, blood flow to brain |
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immune cell-macrophage regulates brain communication helps with neuron growth and connectivity |
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wrap around larger nerves helps transmissions stay in nerve and travel faster |
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line central cavity of brain and spine circulates cerebrospinal fluid |
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satellite and schwann cells |
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PNS surrounds neuron cell body, and controls chemical environment |
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PNS forms myelin sheath in PNS removes damaged nerves helps with nerve fiber regeneration |
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long lived, dont reproduce, high metabolic rate |
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lots of O2 and glucose 20% body energy , 15% cardiac input |
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cell body, dendrite, axon |
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short process that branches like a tree receives input |
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only one per neuron end branches are called telodendria base of axon is spike initiation zone has myelin sheath |
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phospholipid layer that increases speed of nerve impulses protection and insulation |
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bare area on axon where AP is regenerated |
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at least two dendrites and axon |
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only one axon that is directly connected to dendrite |
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active transport and open/close ligand gated, voltage gated, mechanically gated |
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gated channel opens in response to neurotransmitter, hormone, or ions binding of chemical to gate opens it |
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gated channel open in response to current used with AP's activation gates open, inactivation gates close |
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gated channel opens in response to sound waves, pressure and stretching force distorts the channel open. |
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resting membrane potential |
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positive on the outside, negative on the inside oustide has more Na+. inside has more K+ 75X more permeable to K than Na sodium potassium pump prevents equilibrium |
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ion pumps (sodium potassium) |
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driven by ATP slower than open channel moves 3 Na+ in, causes ATP to split, changes shape of gate, 2K+ go into gate, reconfigures and lets 2K+ out |
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graded and action potential |
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causes inside of membrane to be less negative increases chance of AP releases KE in form of current |
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local depolarization produced by stimulation of voltage gates for Na+ |
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only in neurons and muscle cells doesnt degrade with distance four steps: resting state, depolarizing phase, repolarizing, and undershoot |
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resting membrane potential is -70 mV |
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depolarizing phase local current depolarizes spike initiation Na+ gates open interior membrane gets more positive until -55mV (threshold) becomes self generating due to positive feedback at 30mV, Na+ inactivation gates close |
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repolarizing phase K+ moves out of cell and cell repolarizes to resting level |
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undershoot slightly more K+ leaves than necessary sodium potassium pump restores ionic balance |
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movement of Na+ causes other Na+ gates to open |
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coding for stimulus intensity |
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FM and AM FM is used because all AP are of equal magnitude |
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when a neuron cannot generate AP absolute and relative |
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absolute refractory period |
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top of graph, causes AP to go in one direction |
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relative refractory period |
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follows absolute refractory period Na+ gates are resting and K+ are open at this point threshold is higher than resting-normal stimulus cannot generate multiple AP strong stimulus can though |
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depends on axon diameter and myelin sheathing larger diameter, faster the potential |
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prevents degradation of AP bare spots between sheath is node of ranvier all Na+ and K+ is located here AP jumps from node to node-salutatory conduction |
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prevents degradation of AP bare spots between sheath is node of ranvier all Na+ and K+ is located here AP jumps from node to node-salutatory conduction |
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junction between two neurons or neuron and effector cell electrical, excitatory, chemical, inhibitory |
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connected by bridged junction permits rapid, synchronization of AP found in brain |
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most common synapse that uses neurotransmitter axon terminal, synaptic cleft, receptor region |
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neurotransmitter depolarizes the postsynaptic membrane binding of neurotransmitter causes opening of Na+ channels |
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neurotransmitter hyperpolarizes the postsynaptic membrane opens ion channel that increases membrane potential to -80mV |
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inactivation by enzymatic degradation |
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neurotransmitter is broken down by an enzyme |
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transporter proteins take neurotransmitter back into axon terminal |
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types of neurotransmitters |
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acetylcholine, biogenic amines, amino acids, neuropeptides, ATP, and NO2 |
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used in skeletal muscle stimulation and some autonomic nervous system |
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serotonin, epinephrine function as emotional behavior and clock |
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endorphins mediator of pain signals |
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used as a vascular toning agent |
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one incoming fiber triggers response in increasing # of neurons amplifies signal |
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terminates in one neuron concentrates stimulation into one place |
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signal goes through a series of neurons, each of which is connected to a previous one. signal is rejuvenated continuous signal until one neuron is inhibited used in rhythmic activities |
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parallel after discharge circuits |
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single neuron stimulates several which then stimulate a single output neuron burst of impulses after initial input |
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