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Nervous System
Page 3
17
Anatomy
11th Grade
10/14/2010

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Term
__ types of synaptic transmission
Definition

2

electrical

chemical

Term
Synapse
Definition
place where signals are transmitted from one neuron (presynaptic neuron) to another neuron (postsynaptic neuron)
Term
Chemical synapse
Definition

3 structures

-synaptic knob

-synaptic cleft

-plasma membrane of a postsynaptic neuron

Term
Synaptic knob
Definition
tiny bulge at end of presynaptic neuron's axon, contains neurotransmitters
Term
Synaptic cleft
Definition
space between presynaptic and postsynaptic neuron
Term
Plasma membrane of a postsynaptic neuron
Definition
contains protien receptors for neurotransmitters
Term
Synaptic transmission
Definition
action potential reaches knob, Ca++ channels open and cause neurotransmitters to be released across synaptic cleft to the plasma membrane of the postsynaptic neuron, impulse continues
Term
Neurotransmitters
Definition

-released and bind to receptors on the postsynaptic cell

-classified by function and by chemical structure

-4 main types

Term
4 main types of neurotransmitters
Definition

-acetylcholine

-amines

-amino acids

-other small molecules

Term
Amines
Definition

-found in brain

-seratonin and histamine

-catecholamines

Term
Catecholamines
Definition
Dopamine (cocaine blocks uptake of dopamine), epinephrine and norepinephrine
Term
Severe depression
Definition
results from insufficient amines in the brain
Term
Most disorders of nervous system involve _______ rather than _______
Definition
glia, neurons
Term
Multiple sclerosis
Definition
disorder of oligodendrocyte; myelin destruction and loss due to autoimmunity and/or viral infections
Term
Glioma
Definition
most common type of brain tumor, usually benign, but still life threatening
Term
Glioblastoma multiforme
Definition
highly malignant form of an astrocytic tumor, spreads in white matter of the brain
Term
Multiple neurofibromatosis
Definition
numerous fibrous neuromas throughout the body, severe disfiguration
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