Term
| Who is eligible for kidney transplant? |
|
Definition
end-stage kidney disease patients and patients w/eGFT <20ml/min that is irreversible
must undergo medical and psychosocial screening before being listed |
|
|
Term
| What is the difference in a transplanted kidney from normal? |
|
Definition
no valve (pressure refluxes into kidney)
ureter is short
artery can come w/arterial patch
hydronephrosis is over-called and urinary retention is under-called |
|
|
Term
| hyperacute allograft rejection |
|
Definition
| recipient has pre-formed cytotoxic antibodies directed against host donor cells (usually against MHC class I) |
|
|
Term
| acute allograft rejection |
|
Definition
|
|
Term
| What are side effects of calcineurin inhibitors? |
|
Definition
| hepatotox, HT, hypercholesterolemia, glucose intolerance, neurotoxicity (tremor, headache, insomnia, paresthesia) |
|
|
Term
| What are tacrolimus and cyclosporine? |
|
Definition
|
|
Term
| What is the single most important determinant of graft outcome? |
|
Definition
|
|
Term
| What is chronic allograft dysfunction? |
|
Definition
| a poorly defined entity characterized by gradual but progressive arteriosclerosis and/or parenchymal fibrosis of the organ |
|
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