Shared Flashcard Set

Details

Neoplastic Disorders
Test 4 Sem 2
19
Medical
Graduate
03/01/2011

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Cards

Term
What is the most common type of solid tumor in children?
Definition
Brain tumors
Term
What is the only established environmental cause of brain tumors?
Definition
exposure to ionizing radiation
Term
Gliomas develop in 14% of patients with what?
Definition
neurofibromatosis type 1
Term
What is the most common symptom of increased ICP and is the presenting symptom in 40% of brain tumor patients?
Definition
Headache
Term
What is the most common focal sign with brain tumors?
Definition
seizures
Term
What is needed for definitive diagnosis with brain tumors?
Definition
biopsy
Term
What is the drug of choice to decrease ICP and reduce edema from tumor?
Definition
dexamethasone (Decadron)
Term
What is the most common primary brain tumor in adults?
Definition
Astrocytoma grade IV
Term
What type of brain tumor is more common than primary CNS tumors?
Definition
metastases from other cancers
Term
What are the three most common cancers that metastasize to the brain?
Definition
*1) lung
2) breast
3) melanoma
*Most common
Term
What should you suspect with a patient who has a history of cancer and back pain?
Definition
cord compression - surgical emergency
Term
cord compression tumors are more common in what area of the spine?
Definition
thoracic
Term
headache, nausea, and vomiting following radiation treatment should be thought to be caused by what?
Definition
encephalopathy
Term
What is a late delayed brain injury from radiation?
Definition
dementia
Term
Increasing age is a strong risk factor for what type of tumors?
Definition
gliomas, especially glioblastoma multiforme
Term
What are three major clinical syndromes common to CNS tumors?
Definition
1) steady progression of a focal neurologic deficit
2) Seizures
3) "nonfocal" neurologic disorder
Term
What are brain tumor patients at a higher risk for vascularly?
Definition
DVT and PE - put on antithrombolytics, LMWH preferred
Term
What is the most common benign CNS tumor in adults?
Definition
meningioma
Term
What is the most important advance in treating grade 4 glioblastomas?
Definition
temozolomide with radiation
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