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| C kit RTK's found where and what do you treat it with |
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GIST Tumors
Trastuzumab
AKA Her-2/neu |
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Breast cancer
Erb B2 aka Her2/neu |
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100% in Hairy Cell
60% in Melanomas |
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| Activation of RAS through what |
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Definition
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| Mutation of RAS does what |
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| makes it unresponsive to Cetuximab treament |
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| Drug for GIST tumors and Bcr-abl (CML) |
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a Nonrecptor Tyrosine Kinase that is involved in
- Polycythemia Vera
- Primary (Essential) Thrombocythemia
- Primary Myelofibrosis |
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over production in Burkitt Lymphoma
t(8;14) |
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| Small Cell Carcinoma of the Lung |
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