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NBEO Part 2 (2nd sesh)
Still Saving Vision
89
Medical
Graduate
11/03/2014

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Cards

Term
What are the 3 categories for CRVO?
Definition
1. Ischemic
2. Non-ischemic (67%)
3. Papillophlebitis
Term
What is the definition of ischemic CRVO?
Definition
10 DD of non-perfusion on IVFA
Term
4 risk factors for CRVO
Definition
1. HTN
2. DM
3. POAG
4. Cardiovascular disease
Term
4 risk factors for CRAO
Definition
1. HTN
2. DM
3. Carotid Occlusive Dz
4. Cardiac valve Dz
Term
What is the leading cause of visual loss in both ischemic and non-ischemic CRVO?
Definition
Macular edema
Term
If you don't have an IVFA, how can you tell if a CRVO is ischemic or not?
Definition
Ischemic-- 20/200 VA or WORSE
Non-ischemic-- usually 20/40 ish
Term
What is the percentage of ishemic CRVO that causes neo? What about neo glc?
Definition
60%
30%
Term
What percent of CRAOs OR BRAOs happen in the second eye?
Definition
10%
Term
MCC of BRAO
Definition
Hollenhorst plaque
Term
If you have a CRAO or BRAO with an older person, how should you manage this?
Definition
Think GCA, order CRP
Term
How do you predict final VA in someone with CRVO?
Definition
Same as their entering VA
Term
What is the most common cause of a vitreous hemorrahge?
Definition
Diabetes (54%)
Term
3 treatment options for CRAO or BRAO
Definition
1. Digital ocular massage
2. Carbogen treatment (95% O2, 5% CO2)
3. Hyperbaric oxygen chamber therapy
4. Glc meds **
Term
How do you treat optic neuritis if you want to speed up recovery?
Definition
IV steroids for 3 days followed by oral steroids for 11 days
Term
4 main causes of night blindness
Definition
1. RP
2. Choroideremia
3. Fundus albipunctatus
4. Gyrate Atrophy
Term
What is the name of the condition that causes STATIONARY night blindness?
Definition
Fundus albipunctatus
Term
Triad for RP
Definition
1. Bone spicules
2. Waxy disc pallor
3. Arterial attenuation
Term
What does gyrate atrophy look like?
Definition
Midperipheral, scalloped areas
Term
Who is most likely to get choroideremia?
Definition
Young boy (X-linked) -- will have blond fundus (bc of degeneration of RPE and choriocapillaris)
Term
What does fundus albipunctatus look like?
Definition
Yellow-white dots at the level of the RPE
Term
What is a variant of RP that has white dots in fundus?
Definition
Retinitis punctata albescens
Term
What's an oral treatment you can give for RP?
Definition
Vitamin A supplements
Term
What is a really common side effect of vitrectomy?
Definition
Cataract
Term
Risk of getting wet ARMD in the other eye in 5 years?
Definition
40-85%
Term
Likelihood of recurrence in CSR
Definition
40%
Term
What is the name for mild ERM? What about more severe ERM?
Definition
Mild= celluphane retinopathy
Severe= Macular pucker
Term
What is "Smoke stack" appearance associated with?
Definition
CSR
Term
What gender and race is ARMD most common in?
What is the increased percentage of ARMD if you smoke?
Definition
white, female
2.5 times
Term
What are the 4 main risk factors that increase the conversion from dry to wet AMD
Definition
1. HTN
2. Smoking
3. Multiple soft drusen
4. Focal hyperpigmentation
Term
Is hard drusen a risk factor for advancement to wet AMD?
Definition
NO!
Term
What is the cause of histoplasmosis?
Definition
Fungus. Mainly from bat or bird poop. Can cause metamorphopsia *
Term
What percent of CSR patients will get 20/20 vision?
How long does it take for the CSR to go away?
Definition
2/3
1-3 mos (can do laser but may not improve)
Term
What is the expected VA for ERM?
Definition
Half of the initial acuity
Term
How much zinc should you get in your body?
How much did the original AREDs formula have?
Definition
No more than 30 mg/day
80 mg
Term
What's the difference between a classic and occult CNVM?
Definition
Classic- well defined membrane filling early in the IVFA
Occult- poorly defined membrane with later and less intense FL
Term
What is Visudyne and when do you use it?
Definition
It is a tx for ARMD but it is NOT an ANTI-VEGF one. It's used for tx of predominantly classiv CNV. It uses laser too
Term
What's the classification of CNV?
Definition
1. Subfoveal
2. Juxtafoveal
3. Extrafoveal
Term
What is different about Macugen (anti veg F) and lucentis/avastin
Definition
Macugen stops new neo but does NOT improve vision. Lucentis/avastin does improve vision
Term
What's the difference between grade 1 and 2 HTN ret?
Definition
Grade 1- arterial narrowing
Grade 2- A/V nicking
Term
What is endophytic and exophytic association with?
Definition
Retinoblastoma
Endophytic-- tumor in anterior retina growing in toward vitreous
Exophytic-- tumor in posterior retina growing toward choroid
Term
What is pica associated with?
Definition
Ocular toxocariasis -- eating dirt
Term
Is Coats dz bilateral or unilateral?
Definition
Unilateral
Term
Signs of Retinoblastoma
Definition
1. Leukocoria
2. Stabismus
3. Iris neo
4. Decreased findings
Term
What is the most common cause of infectious retinitis?
Definition
Toxoplasmosis
Term
What does the ERG measure?
Definition
Arden ratio -- should be MORE than 1.6 in normals
Term
What is etiology of histoplasmosis and toxoplasmosis?
Definition
Histo= fungi
Toxo= parasite
Term
What are the importance grades in Best's disease?
Definition
Grade 2- egg yolk formation
Grade 4- vitelliruptive -- bad vision
Term
What is the egg yolk made up with in Best's disease?
Definition
Lipofuscin
Term
What is worst case scenario with Best's Dz
Definition
CNV
Term
What is the most common hereditary macular dystrophy?
Definition
Stargardt macular dystrophy
Term
What would Stargardt's mild, mod, severe look like?
Definition
early- RPE mottling, loss of FLR
middle- yellow flecks
late- beaten bronze macular, salt and pepper pigment changes
Term
Tx of toxoplasmosis
Definition
1. Oral steroid
2. Pyrimethamine or sulfadizine
Term
What big condition can high lipidemia cause?
Definition
Ocular ischemic syndrome
Term
Visual prognosis for ocular ischemic syndrome
Definition
90% CF or worse after 1 year !! Wow
Term
Dif between venous stasis ret and ocular ischemic syndrome?
Definition
Venous stasis- mid peripheral hemorrhages but NO A seg issues
Ocular ischemic syndrome- venous stasis and a seg issues (like iris rubeosis)
Term
What is normal cholesterol levels?
Definition
Total- 200
HDL -- >40
LDL -- <100
Triglucerides < 150
Term
What are the High Risk Characteristics?
Definition
1. Neo within 1/4 DD of disc
2. NVE with vitreous or preretinal hemorrhage
Term
What's the reason for dibetics going blind?
Definition
macular edema
Term
What percent of severe NPDR will develop proliferative in 1 year?
Definition
10-50%
Now you need to see them every 3 mos
Term
What is the treatment for macular edema?
Definition
ETDRS- focal argon laser
RESTORE- Lucentis
Term
What is the most importance risk factor for someone to get DR?
Definition
Length of time having DM
Term
What is sensitivity?
Definition
Given the patient is positive, the probability of the test showing positive result
Term
What is positive predictive value?
Definition
Given a positive test result, the probability that the patient has a positive
Term
What is the most common cause of a CN 3 palsy?
Definition
aneurysm of posterior communicating artery
Term
4 contributors to idiopathic intracranial hypertension
Definition
CANT
1. Contraceptives
2. Vitamin A and Accutane
3. Naladixic acid
4. Tetracycline (minocycline)
Term
How does Acetazolamide help with papilledema?
Definition
Decreases CSF production
Term
Signs/symptoms of pseudotumor cerebri (idiopathic intracranial hypertension)
Definition
1. HA
2. CN 6 palsy
3. Transient visual obscurations
4. Enlarged blind spot
Term
What is a normal CSF pressure during LP?
Definition
<200 in normal people
<250 in normal, obese people
Term
9 SE of Acetazolamide
Definition
1. Metallic taste
2. Metabolic acidosis
3. Depression
4. Diarrhea
5. Thrombocytopenia
6. Aplastic anemia
7. Agranulocytosis
8. Transient myopia
9. Tingling hands/feet
Term
What type of VF defect is most commonly seen in MS patients?
Definition
central scotoma
Term
What is a normal CRP result?
Definition
0-1 mg/dL
Term
How is Leber's optic neuropathy inherited?
Definition
mitrochondrial DNA
Term
Risk of MS over 10 years-- if..
1. No white matter on MRI
2. 1 or more white matter on MRI
Definition
1. 22%
2. 56%
Term
What does the CHAMPS study say about MS?
Definition
If you have 2 or more MRI white matter lesions, use IV steroids and interferon-beta for a delayed onset of MS and reduction in lesions
Term
Why do some patients with MS develop diplopia?
Definition
They get INO -- caused by lesion in the MLF.
Get an AD-duction deficit on side with the lesion and an AB-duction nystagmus on the contralateral side.
Term
Exophthalmometry norms
Definition
18, 22, 24
Asians, Whites, blacks
12 is the beginning
>3 mm difference is abnormal
Term
What EOM position is restriction the greated in Brown's syndrome?
Definition
upgaze esp when adducted
Term
How to treat optic nerve compression with TED (other than sx)
Definition
prednisone 100 mg qday x 2-14 days
Term
prior to a NAION, what does the disc look like?
Definition
disc at risk-- small, crowded disc with minimal cupping
Term
What type of visual field defect occurs in an NAION
Definition
inferior altitudinal
Term
3 other causes of A-AION besides GCA
Definition
1. Polyarteritis nodosa
2. Lupus
3. Herpes Zoster
Term
What do steroids do to blood pressure?
Definition
Raise blood pressure
Term
What CN palsy can Horner's syndrome cause?
Definition
CN 6
Term
What drug do you use in the tensilon test for MG?
What drug is used as the antidote for that drug?
Definition
Edrophonium (inhibits acetylcholinesterase)
Atropine
Term
What tests should be ordered if you suspect MG?
Definition
1. Tensilon Test
2. Chest CT (thymus tumor)
3. TSH, T3, T4
Term
What type of receptors does Flomax work on?
Definition
Alpha 1 blocker
Term
What drug can you give to treat someone with MG?
Definition
Pyridostigmine (long acting acetylcholinesterase inhibitor)
Term
Why do you order blood work on someone with a suspected pituitary ademona?
Definition
check if it's prolactin secreting (functional) or not (non functional)
*Pit adenomas can cause amenorrhea and galactorrhea
Term
What is the treatment of a pituitary adenoma
Definition
Bromocriptine (dopamine agonist--shrinks the tumor)
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