Term
| What is the MOA, suffix, and SE of ACE inhibitors? |
|
Definition
MOA: Inhibits angiotensin II by blocking Angiotensin Converting Enzyme (ACE) --> lower BP; blocks metabolism of bradykinins --> bronchodilation
Suffix: -pril
SE: Dry cough |
|
|
Term
| What is the MOA and suffix of ARB's? |
|
Definition
MOA: Angitotensin II inhibition --> smooth muscle relaxation --> lower BP
Suffix: sartan |
|
|
Term
| What are the two systemic alpha-1 blockers? |
|
Definition
|
|
Term
| What is the systemic alpha-2 blocker? |
|
Definition
|
|
Term
| What is a CCB with an ocular use? |
|
Definition
| Nifedipine; used in tx of normotensive glaucoma |
|
|
Term
| What are the two CCB's used for cardiac issues but not any ocular conditions? |
|
Definition
|
|
Term
| What is the MOA and SE of Hyralazine? |
|
Definition
MOA: Increases cGMP --> smooth muscle relaxation --> lower BP
SE: lacrimation, fluid retention |
|
|
Term
| What is the MOA of digoxin? |
|
Definition
| Inhibits Na+/K+ pumps --> Increase intracellular Ca+ --> increased heart contractility |
|
|
Term
| What is a Class 1 Anti-arrythmic drug? |
|
Definition
| Na+ channel blocker (Digoxin) |
|
|
Term
| What is a Class 2 Anti-arrythmic drug? |
|
Definition
|
|
Term
| What is a secondary MOA of non-selective beta-blockers? |
|
Definition
| block release of renin from the kidneys |
|
|
Term
| What is a Class 3 Anti-arrythmic drug? |
|
Definition
|
|
Term
| What is a Class 4 Anti-arrythmic drug? |
|
Definition
|
|
Term
| What is the mechanism of amiodarone? |
|
Definition
|
|
Term
| What is variant or Prinzmetal's angina? |
|
Definition
| Rare angina w/ coronary artery spasms |
|
|
Term
| What is the tx for unstable angina? |
|
Definition
| Immediately administer 325 mg ASA (4 baby aspirin), morphine, oxygen, and nitroglycerine |
|
|
