Term
| List common transplanted organs |
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Definition
| liver, heart, kidney, pancreas, and lung |
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Term
| Terms: Allograft transplant |
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Definition
| same species, but not genetically identical |
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Term
| Terms: Acute graft rejection |
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Definition
| occurs w/in in 6mo of transplant |
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Term
| Terms: Hyperacute graft rejection |
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Definition
| occurs w/in minutes to hours of transplant |
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Term
| Terms: Chronic organ rejection |
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Definition
| lifetime risk; prevent w/ maintenance immunosupression |
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Term
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Definition
| higher levels of drugs used during initial post transplant period |
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Term
| Pearls: antithymocyte globulin |
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Definition
Brand: Thymoglobulin (rabbit)
Dosing: IV
*No live vaccines
** refrigerate; stable for 24h after reconstituted |
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Term
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Definition
Class S/E: risk of infection, hypergylcemia, osteoperosis, increase appetite, irritability, insomnia, weight gain, PUD, HTN
Taper if d/c after long period of use |
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Term
Pearls: mycophenolate mofetil
Mycophenolic Acid |
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Definition
Brand: MM = Cellcept, MA = Myfortic
Dosing MM = IV/PO, MA = PO
DI: Bile acid sequestrants, cholestyramine
*Take on empty stomach |
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Term
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Definition
Brand: Neoral, Gengraf, SandIMMUNE
Dosing: IV + PO
**Monitored by trough concentrations (100-400) |
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Term
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Definition
Brand: Pprograf, Astagraf, Hecoria
Dosing: PO + IV
**Monitored via trough concentrations (5-20)
***3A4 substrates
***Can take w/ or w/o food, but need to be consistent |
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Term
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Definition
Brand: Rapimune
Dosing: PO
DI: incr nephro tox when combined w/ calcinurin inhibitor
**Monitored via serum drug conc. (15-25) |
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Term
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Definition
Brand: Afinitor, Afinito, Disperz, Zortress
Dosing: PO
**Monitor whole blood trough concentrations (5-15) |
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Term
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Definition
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Term
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Definition
Tuberculosis (BCG)
Oral Polio Vaccine
Measles, mumps, rubella (MMR combined vaccine)
Rotavirus
Smallpox
Chickenpox (Varicella)
Yellow fever |
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