Term
| Pathology < 12 hours post-MI |
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Definition
No gross changes
Wavy myocardial fibers on histology |
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Term
| Pathology 12-24 hours post-MI |
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Definition
Gross = dark mottling
Histo = coagulative necrosis |
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Term
| Pathology 24-72 hrs post-MI |
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Definition
Gross = pale yellow
Histo = neutrophils |
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Term
| Pathology 3-7 days post-MI |
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Definition
Gross = yellow and well defined
Histo = lysis of dead muscle cells; early phagocytosis by macrophages |
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Term
| Pathology 1-4 weeks post-MI |
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Definition
Gross = soft and pale to shrunken and purple
Histology = prominent capillary growth (granulation tissue); collagen deposition by fibroblasts; phagocytosis of necrotic myocardium |
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Term
| Pathology 8 weeks post-MI |
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Definition
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Term
|
Definition
MB = rises @ 2-4 hrs, peaks at 18 hrs, normal @ 48 hrs
Troponin 1 = rises quickly, elebated 4-7 days
Lactate dehydrogenase = normal LD1< LD2 in blood; in MI, LD1>LD2, rises by day 3 |
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