Term
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Definition
-Gram aerobic (+) rod shaped bacteria
-acid fast bacillus within macrophages on stain, saprophytic and pathogenic lifestyles
- has outer mycolic acid in their cell wall with a little peptidogylcan
-outer mycolic acid retains acid fast stain, and give protection and resistance |
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Term
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Mycobacterium bovis *zoonotic |
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Definition
-causes bovine tuberculosis
-natural reservoirs are captive elk, deer, bison
-pasteurization may not kill organism
Transmission: most common-- Inhale, ingest
-Organism disseminates via lymph and lodges in lungs, spleen, liver
-Localized lesions of lymph nodes of the head and lungs are also noted
-Progression is slow and requires 1-5 years before clinical
signs become apparent. |
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Term
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Definition
Clincal Signs: appear in late stage disease coughing, emaciation, dyspnea, increased respiration, nodules on organs |
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Term
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Definition
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Diagnose: culture or impression smear
Tuberculin skin test—caudal fold test followed by comparative cervical test
- Type IV hypersensitivity reaction
Treatment: none for cattle because it is zoonotic, depopulate |
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Term
Mycobacterium avium subspecies paratuberculosis |
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Definition
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- Causes Johne’s Disease
- in domestic ruminants, wildlife, and possibly humans (Chron’s disease)
-stimulates growth in the intestines causing malabsorption of nutrients |
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Term
Mycobacterium avium subspecies paratuberculosis |
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Definition
Transmission: Ingestion of contaminated feces is the highest form of transmission but also shed in milk, urine, and semen
Clinical Signs: Takes 1-3yr progression of disease to see CS
– Thickening of the intestinal wall due to epithelial cell proliferation
–SEVERE WEIGHT LOSS, Emaciation despite normal appetite
– Swelling of regional lymph nodes (org within macrophages)
--Lymph nodes show caseous necrosis in goats
– Coat becomes dry and rough
– “Bottle jaw”, a mandibular edema caused by protein loss
– Chronic or intermittent diarrhea |
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Term
Mycobacterium avium subspecies paratuberculosis |
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Definition
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Diagnosis: Fecal culture, Serum ELISA, DTH test using johnin, but don’t see accuracy until late stage
Treatment: NONE, depopulate due to poss zoonotic |
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