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Mutations
n/a
15
Biology
9th Grade
12/05/2011

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Term
Mutation?
Definition
-Any alteration in the nucleotide base sequence in the DNA molecule.
Term
What are the two reasons for DNA mutation? Which is more common?
Definition
1.Small errors that occur during replication. 2. Mutagens damaging the DNA
Term
What is a mutagen?
Definition
chemicals or radiation
Term
What do mutagens result in?
Definition
Increased genetic variation that damages the DNA
Term
Mutations result in the ultimate source of what?
Definition
New genes
Term
Substitution mutation can also be called what?
Definition
Point mutation
Term
What happens in point mutation?
Definition
1 nucleotide base is substituted for another changing the sequence of bases
Term
What is a neutral mutation?
Definition
Where the new code word is the same amino acid as the original so there is no change in the amino acid sequence
Term
What is a missense mutation?
Definition
The new code word codes for a different amino acid than the original so the amino acid sequence is different and may not function properly
Term
What is a nonsense mutation?
Definition
The new code word is a termination codon that sends a premature stop signal, and the protein is not produced at all
Term
What is frameshift mutation?
Definition
A nucleotide is either deleted or added
Term
What is the result of frameshift mutation?
Definition
every amino acid following the mutation will be changed
Term
What are the 4 types of chromosomal mutations?
Definition
deletion, duplication, inversion, and translocation
Term
What is inversion mutation?
Definition
a chromosome breaks off and reattaches in reverse
Term
what is translocation mutation?
Definition
a chromosome breaks off and attaches to another chromosome
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