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IIA and IIB - white color; little mitochondria (glycolytic); high sarcoplasmic reticular Ca2+ capacity; high fatigability |
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type I - phospholamban (inhibits SRCa fibers) is inhibited by epinephrine; Red from mitochondrial capacity (oxidative); low fatigability |
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Definition
calmodulin is Ca2+ sensor (multiple isoforms) |
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Definition
inhibits SRCa fibers; is inhibited by epinephrine; slow, cardiac and smooth muscles - sympathetic nervous system activation |
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frequency is high enough to maintain calcium at a constant high level; allows constaint force for smooth movements |
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no change to force, incresed velocity and shortening capacity |
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Definition
force increases but velocity and shortening capacity does not change |
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ubiquitin ligase; inhibtis transcription by exporting transcription factors; leads to decrease protein synth and increased degradation; causes atrophy of muscles |
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Definition
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Ach receptors spread out and cause eratic stimulation; with in 8-12 months atrophy occurs due to lack of stimulation |
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Definition
force is held constant - measure change in lenght of muscle |
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Definition
the length of the muscle is constant and the force generated is measured |
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