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Muscles
Mamphys Exam I
18
Biology
Undergraduate 3
10/04/2010

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Term
Skeletal fibers
Definition
Striated - sarcomeres (long, multinucleate)
Term
Skeletal contractile elements
Definition
Actin, myosin, troponin, tropomyosin
Term
Skeletal intracellular compartments
Definition
T-tubule, sarcoplasmic reticulum, many mitochondria (need energy)
Term
Skeletal E-C coupling
Definition
AP --> DHPR --> RyR --> Ca release --> Ca-TnC --> cross-bridges --> stroke
Term
Skeletal control
Definition
voluntary - individual fiber innervation via motor neurons (motor units)
Term
Skeletal contraction of individual fiber
Definition
All-or-nothing
Term
Cardiac fibers
Definition
Striated - sarcomeres (short, branched, uninucleate)
Term
Cardiac contractile elements
Definition
Actin, myosin, troponin, tropomyosin
Term
Cardiac intracellular compartments
Definition
Sarcoplasmic reticulum, many mitochondria (need energy)
Term
Cardiac E-C coupling
Definition
AP --> DHPR --> Ca influx --> RyR --> Ca release --> Ca-TnC --> cross-bridges --> stroke
Term
Cardiac control
Definition
Involuntary, autorhytmic, modulated by ANS (Epi, ACh), interconnected via gap junctions
Term
Cardiac contraction of individual fiber
Definition
Graded (variable force)
Term
Smooth fibers
Definition
Longitudinal bundles (small, spindle-shaped, uninucleate)
Term
Smooth contractile elements
Definition
Actin, myosin, tropomyosin
Term
Smooth intracellular compartments
Definition
Sarcoplasmic reticulum (less)
Term
Smooth E-C coupling
Definition
Ca influx --> active CAM binds to MLCK --> phosphorylation of MLC --> cross-bridge formation --> force
Term
Smooth control
Definition
Involuntary, some are autorhytmic, innervated by ANS, respond to hormones, interconnected via gap junctions
Term
Smooth contraction of individual fiber
Definition
Graded (variable force)
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