Term
| Facts about Skeletal Muscle |
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Definition
--Each skeletal muscle is a single organ composed of skeletal muscle tissue(composed of muscle fiber.
--Each muslce is structurally organized in bundles that are separated by connective tissue sheaths.
--CT sheaths support and reinforce muscle preventing bursting during strong contractions. |
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Term
| Gross Microscopic Anatomy: Skeletal Muscle |
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Definition
1.Muscle
2.Fascicles
3.Muscle Fibers(cells)
4.Myofibrils
5.Thick and thin filaments |
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Term
| Connective Tissue Coverings |
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Definition
| Fascia, epimysium, perimysium, endomysium |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Separates individual fasciles |
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Term
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Definition
| Wraps individual muscle fibers |
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Term
| Skeletal Muscle: Innervation and Vascularization |
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Definition
--Uses large amounts of energy(needs constant oxygen supply and nutrients)
--Each muscle has but one nerve and artery and at least one vein
--Multiple capillaries adapted for muscle movement (look like squiggles) |
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Term
| Skeletal Muscle Microscopic Anatomy |
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Definition
--Muscle fiber(is a single cell)
--Relatively large in diameter and long
--Each Muscle fiber is surrounded by sarcolemma and contains sarcoplasm.
--T tubules (sarcolemmal modifications)
--Sarcoplams contains large amounts of glycosomes, myoglobin (red, oxygen storing pigment), myofibrils and specialized sarcoplasmic reticulum. |
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Term
| Thick Filament system: Myosin found in A Bands |
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Definition
| The thick filament system is composed of Myosin protein which is connected from the M-line to the Z-disc by titin. It also contains myosin-binding protein C which binds at one end to the thick filament and the other to Actin. |
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Term
| Thin filament system: Actin found in I band |
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Definition
| The thin filaments are assembled by Actin monomers bound to nebulin, which also involves tropomyosin (a dimer which coils itself around the F-actin core of the thin filament) and troponin. |
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Term
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Definition
| Composed of thin Actin Filaments |
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Term
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Definition
| Composed of thick Myosin Filaments |
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Term
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Definition
| Central region of the A band, where actin and myosin do NOT overlap |
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Term
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Definition
| In I bands, consist of proteins (Nebulin) that hold actin filament in place |
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Term
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Definition
| In A bands, consist of proteins (Titin) that hold myosin filaments in place |
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Term
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Definition
Found in the thin filament, composed of Actin and it's main functions are:
-Help stiffen Actin core
-Block Actin-myosin binding sites at rest |
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Term
| Troponin (3-polypeptide complex) |
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Definition
| A complex of muscle proteins which, when combined with Ca++, influence tropomyosin to initiate contraction. |
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