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spontaneously assembled from collagen subtypes I-IV - fibrilogenesis; 4-fold staggered overlap; form thick, eosinophilic FIBERS |
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alternating I (light) and A (dark) bands |
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fast twitch, glycolytic, fatigueable |
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slow twitch; oxidative; repetitive |
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O2-binding protein; closely resembles hemoglobin; varying amounts in muscle fibers |
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dense CT; surrounds collection of fascicles |
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functional units of muscle fibers that tend to work together to perform a specific function; surrounded by perimysium |
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thicker CT; surrounds group of fibers; forms bundle or fascicle |
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reticular fibers that surround individual muscle fibers; small-diameter blood vessels; neuronal branches (very fine) fun parallel |
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muscle fiber plasma membrane and endomysium |
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morphologically identical to skeletal muscle; soft tissues: tongue, pharynx, diaphragm, esophagus |
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myofilament; primarily myosin II; about 15 nm diameter |
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myofilament; primarily actin; 6-8 nm diameter |
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Definition
tethers thin filaments from adjacent sarcomeres to common Z-line |
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stretchable ("elastic") protein linking thick filament to Z-line; largest known protein |
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Definition
light, central region of dark A-band; ONLY myosin |
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middle line of H band; each myosin joined laterally to its myosin neighbor |
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isotropic; DOESN'T bend polarized light - appears bright only thin actin filaments; width DECREASES during contraction |
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Z = "between"; middle line of I band contains actin-binding proteins (alpha-actinin) which link actin of consecutive sarcomeres; demarcates sarcomeres |
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Definition
fuse during development to form multinucleated syncytia - muscle fibers |
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one complex binds to one tropomyosin which binds to actin TnT = binds tropomyosin TnC = finds Ca2+ to initiate contraction TnI = binds actin and inhibits actin-myosin interaction |
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Definition
links actin of sarcomeres to laminin in external lamina; largest known gene |
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