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What types of muscle tissue are there? |
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What types of striated muscle are there? |
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Describe the heirarchical organization of muscle tissue |
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Muscle>Fasicle>Fiber>Myofibril>Myofilament |
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True or false: Myofilaments are surrounded by connective tissue |
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True or false: Myofibrils are surrounded with CT |
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Name the layers of CT surrounding muscle tissue. |
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Endomysium- wrap fiber
Perimysium- wrap fasicle
Epimysium- wrap entire muscle |
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_________ are connected by interconnected network of ER |
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What are the general characteristics of striated muscle cell? |
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Elongated cell
Multinucleated
Nucleus near periphery
Lots of mitochondria |
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What is a triad regarding muscle ? |
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Consist of 2 terminal cisternae and a middle T-tubule |
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An extension of the cytoplasm used to conduct nerve impulse to sarcolemma |
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What are the terminal cisternae's role? |
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differentiate between the two types of myofilaments |
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Thick: myosin with heavy and light subunits (15 nm diameter)
Thin: made of troponin and tropomyosin (5nm diameter) |
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1=Z-band
2= M
3= Z-band
4=I-band
5= A-band
6=H-zone |
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Describe steps of sliding filament model |
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Definition
- Nerve impulse transmits to cell interior of fiber by T-tubule
- Ca ions release from terminal sac and enter sarcoplasm
- Ca binds to troponin, causing transformational change
- Change in troponin cause tropomyosin to move to reveal active sites
- ATP hydrolysis to ADP + Pi (requires Mg)
- Myosin bends while attached to actin
- ATP binds to myosin, and myosin detach from actin
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What is the role of Mg in sliding filament model? |
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Definition
Allows the hydrolysis of ATP to ADP+ PI |
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What is the role of Ca in sliding filament model? |
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Definition
Binds to troponin to change it's conformation. Causes tropomyosin to reveal active site |
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What are two skeletal muscle fiber types? |
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What are the differences between red and white muscle? |
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White: fast twitch, anaerobic, large force, few mitochondria
Red: slow twitch, aerobic, many mitochondria, lots of mito, myoglobin |
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What makes smooth muscle different than striated? |
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Definition
smooth has...
- mononicleated
- Spindle-shaped
- no T-tubule system
- Each cell surrounded by thin CT
- Random arrangement of muscle fiber
- 3 types of filaments: thick, thin, intermediate
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