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1.Nerve impulse arrives at motor neuron axon terminal/triggers release of acetylcholine(Ach) into neuromuscular junction |
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2.Ach diffuse across junction/binds to receptors on motor end plate/triggers action potential to spread along sarcolemma & t-tubules |
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3.Action potential/release of calcium ions from sarcoplasmic reticulum into sarcoplasm |
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4.Calcium binds to troponin on thin filament exposing binding sites for myosin |
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5.CONTRACTION:Cross-bridges form when myosin heads bind to actin on thin filaments. Thin filaments pulled toward center of sarcomere and sarcomere shortens |
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6.Acetylcholinesterase released into neuromuscular junction destroys acetycholine |
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7.Calcium breaks from thin filament/is actively pumped back into sarcoplasmic reticulum (cross-bridges break after contraction) |
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8.RELAXATION:Cross-bridges break releasin thin filament from thick filament/thin filaments slide back to resting position |
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Muscle cells contract to ALL OR NOTHING law |
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the muscle contracts with all its force or nothing at all |
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