Term
| Relapsing-Remitting (RRMS) |
|
Definition
Most forms
Sx develop and resolve in a few weeks - months and pt returns to baseline.
DUring relapse = loss of function and development of new sx |
|
|
Term
| Primary Progressive (PPMS) |
|
Definition
Steady and gradual progression. No relapse. No acute attacks.
Onset generally 40-60 yrs of age |
|
|
Term
| Secondary Progressive (SPMS) |
|
Definition
| Relapsing and remitting that later becomes steadily progressive |
|
|
Term
| Porgressive - Relapsing (PRMS) |
|
Definition
Frequent relapses with PARTIAL recovery.
No return to baseline.
Small percentage of cases |
|
|
Term
| General pathophysiology of MS |
|
Definition
Inflam causes demyelination and atonal injury.
Slows or stops nerve impulses |
|
|
Term
| MS effects CNS/PNS or both? |
|
Definition
CNS only.
PNS = Schwann cells, MS affects oligodendrites. |
|
|
Term
|
Definition
Unknown.
May be triggered by virus or other infectious agent
More common in colder climates
More common in Northern European ancestry
Women 2x affected
Usual onset 20-40 yrs. |
|
|
Term
|
Definition
Stiffness of extremities particularly in legs
Increased fatigue
Spasms at night
+babinski reflex
Unsteady gait, poor coordination or clumsy
Ataxia (decreased moto coordination) |
|
|
Term
|
Definition
Blurred vision
Double vision
Decreaded visual acuity
Scotomas (Changes in peripheral vision)
nystagmus
Tinitis/vertigo |
|
|
Term
|
Definition
| Decreased pain sensitivity (Hypalagesia) and decreased temp sensation |
|
|
Term
|
Definition
Dysfunction.
Sexual dysfunction |
|
|
Term
|
Definition
No single lab test is diagnostic
Abnormal CSF findings:
Elevated protein/WBC count
Increased immunoglobulins (G) |
|
|
Term
|
Definition
MRI
Shows plaques and lesions |
|
|
Term
|
Definition
Dysarthria (slurred speech)
Dysphagia (difficulty swallowing) |
|
|
Term
|
Definition
Safety in regards to weakness/fatigue
Maintainence of mobility
Treating elimination problems/ sexual dysfunction
Manage risk for infection |
|
|
