Term
| What do you need for diagnosis of multiple myeloma with regards to major and minor criteria? (2 possibilities) |
|
Definition
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|
Term
| What ethnic group is multiple myeloma low in and which is it high in? |
|
Definition
low in Asians
high in African Americans |
|
|
Term
| What is the second most common blood maglignacy? |
|
Definition
| multiple myeloma (obviously) |
|
|
Term
What is the peak age of onset for multiple myeloma?
What is happening to this age of onset? |
|
Definition
60-70
the age of onset is decreasing |
|
|
Term
| What chromosome carries the most common cytogenetic abnormality for multiple myeloma? |
|
Definition
|
|
Term
| What two chromosomes are most linked to multiple myeloma? |
|
Definition
|
|
Term
| How is the diagnosis of multiple myeloma usually made (what test)? |
|
Definition
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|
Term
| How many cells in the biopsy must be myeloma plasma cells to even begin to think multiple myeloma in the differential? |
|
Definition
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|
Term
| What is the name given to plasma cells in multiple myeloma, when filled with inclusions? |
|
Definition
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|
Term
| What are the two types of inclusions found in plasma cells in multiple myeloma and where in the cell are they found? |
|
Definition
Russell bodies in cytoplasma
Dutcher in nucleus |
|
|
Term
| WHat marker is found in plasma cells of multiple myeloma? |
|
Definition
|
|
Term
| How does the prognosis of plasma cell leukemia compare to the prognosis of multiple myeloma? |
|
Definition
|
|
Term
| How does the prognosis of plasmacytoma compare to the prognosis of multiple myeloma? |
|
Definition
|
|
Term
| What is true of the rim of the punched out lesions on XRAY of multiple myeloma? |
|
Definition
|
|
Term
| What does POEMS stand for? |
|
Definition
demyelinationg polyneuropathy
organomegally
endocrinopathy
serum M spike
skin lesions |
|
|
Term
| Will light chains be detected in the urine of a standard dip stick urine exam? |
|
Definition
|
|
Term
| What type of amyloidosis is present in mutliple myeloma? |
|
Definition
|
|
Term
| What is the median survival of multiple myeloma patients? |
|
Definition
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|
Term
| What is the typical treatment for solitary lesions in multiple myeloma? |
|
Definition
|
|
Term
What is a common chemo drug used in treatment of multiple myeloma?
Why is it a good treatment? |
|
Definition
melphalan
can be given orally |
|
|
Term
| What are three general treatments for multiple myeloma depending on the stage? |
|
Definition
radiation
chemotherapy
stem cell transplant |
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