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MTCE 3
MTCE 3
49
Biochemistry
Graduate
06/05/2011

Additional Biochemistry Flashcards

 


 

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Term
three types of jaundice
Definition
obstructive, hemolytic, and parenchymal
Term
Trinder Reaction
Definition
ferric chloride is added to a urine sample to react with any salicylate that might be present. turns purple. not exclusive.
Term
EMIT, enzyme-multiplied immunoassay technique
Definition
1: antibody for drug is made and administered; 2: coenzyme and substrate are added for antigen; 3: labelled antigen is added, and competes for antibody, those who don't bind react. Monitored at 340nm, high reaction, high concentration of drug.
Term
ELISA, enzyme-linked immunosorbent assay
Definition
1: make antibodies to the substance of interest (SOI), and mix it therewith. 2: treat the SOI with an enzyme, and add the enzyme-linked SOI to the mixture. 3: add the enzymes substrates to the mix and monitor the reaction with a color analysis.
Term
Progesterone level during the follicular stage
Definition
<2 ng/mL
Term
progesterone level in the luteal stage
Definition
>5ng/mL
Term
Progesterone
Definition
hormone essential to implantation, miscarriage prevention, and lactation.
Term
hCG, human chorionic Gonadotropin
Definition
hormone indicative of pregnancy, high throughout first trimester.
Term
Three levels of endocrine dysfunction
Definition
the gland itself; the pituitary; the hypothalamus
Term
cushing's
Definition
increased production of cortisol due to abnormal production of ACTH, due to adrenal problems or a tumor in the pituitary.
Term
thyroid hormones
Definition
iodine is collected and activated by the related organ, then organified through being bound to the tyrosine residues of TG, TSH then removes the iodine-tyrosine complexes from TG, resulting in T3 and T4
Term
luteinizing hormone, LH
Definition
released only by the pituitary, and signals for ovulation, as well as prepping the uterine wall for implantation
Term
Human Placental Lactogen, HPL
Definition
a protein hormone that allows for the nutrition of the fetus through its effects on the mother's metabolism
Term
Addison's disease
Definition
adrenal glands fail to produce aldosterone and cortisol properly, causing poor Na+ reabsorption, as well as H2O retention, causing a decrease in extracellular fluid, and high H+ and K+ concentrations. This manifests as brownish skin and mucousal membranes, anemia, and weakness
Term
serum anions in order of prevalence
Definition
Cl-, HCO3-, proteins-, lactate, and ketone bodies
Term
determination of inorganic phosphate in serum
Definition
deproteinized serum is treated with molybdate, which will bind the related ion. The molybdate compound can then be reduced to form molybdenum blue, which can be measured spectrophotometrically.
Term
elevated aldolase
Definition
indicitive of many muscular disorders
Term
elevated amylase
Definition
acute pancreatitis
Term
elevated creatine kinase
Definition
damaged brain tissue
Term
elevated levels of alanine and aspartate aminotransferases
Definition
acute hepatitis
Term
elevated alkaline phosphatase
Definition
paget's disease (osteitis deformans)
Term
Weil-Felix test
Definition
the use of proteus vulgaris or some other bacteria, to agglutenate with the antibodies produced in response to a Rickettsial bacterium in the serum
Term
The effect of Vitamin D on Ca levels
Definition
hydroxylization thereof creates a compound which increases the related ion and phosphate absorption in the intestines
Term
PTH's effect on Ca levels
Definition
helps move it from the bones to the blood, as well as assisting in the synthesis of a Vitamin D derivative
Term
Henderson-Hasselbach
Definition
pH = pKa + log([salt]/[acid])
Term
metabolic acidosis
Definition
high production of organic cations in the body, caused by lowered blood pH, renal failure, diabetes, diuretic use
Term
mycobacterium
Definition
aerobic, rod-shaped, hardy cell walls make them difficult to treat; cause tuberculosis and leprosy; can be tested with an acid-fast stain
Term
Enterobacteriaceae
Definition
gram-negative, aerobic, rod shaped; normal flora of healthy intestine, soil, water, plants: E. coli, salmonella
Term
micrococcaceae
Definition
spherical, gram positive, aerobic: some harmful, some healthy flora. M. micrococcus and M. staphylococcus are examples
Term
Nocardiaceae
Definition
aerobic, gram positive, rod. mostly harmful, causing pneumonia, cellulitis, and abcesses
Term
Spirochetes
Definition
anaerobic, spiral, gram-negative. three families: leptospira, borrelia burgdorferi, and treponema pallidum. pathogenic. found in liquid environments
Term
treponema pallidum pertenue
Definition
spirchetes that causes Yaws, transmitted by flies
Term
treponema pallidum pallidum
Definition
spirochetes that causes syphilis
Term
borrelia burgdorferi
Definition
spirochetes that causes lyme disease, deer ticks
Term
leptospira
Definition
spirochetes, infected soil/water
Term
treponema pallidum carateum
Definition
spirochetes responsible for pinta
Term
Rickettsia
Definition
genus of bacteria: small often pathogenic (typhus, scrub typhus, spotted fever), vector driven, responds to tetracycline antibiotics
Term
Rhinovirus
Definition
most common type of virus, very small, airborne, RNA based. common cold.
Term
Alpha and beta group streptococci
Definition
causes several major upper respiratory infections including pneumonia and scarlet fever; it also has minor hemolytic properties. has more advanced hemolytic properties, including white blood cell lysis, and inhibition of clotting.
Term
Kauffman-White classification system
Definition
determining the type of salmonellae present by first classifying the "O" or somatic antigens, associated with the membrane; second, classifying the "H" or flagellar antigens, associated with the flagella of motile salmonellae
Term
Gentamicin
Definition
works through inhibiting protein synthesis, treats urinary tract infections
Term
Vancomycin
Definition
inhibits synthesis of cell walls, can treat upper respiratory infections in patients who are allergic to penicillins
Term
Clindamycin
Definition
interferes with protein synthesis, treats respiratory, and dermatological infections
Term
Rifampin
Definition
interferes with bacterial RNA synthesis, treats tuberculosis
Term
Penicillin
Definition
intereferes with cell-wall synthesis, treats pneumonia
Term
Tetracycline
Definition
interferes with RNA synthesis, can be used to treat respiratory infections
Term
Francisella tularensis
Definition
EA associated with rabbit fever
Term
helicobacter pylori
Definition
EA associated with peptic ulcer disease
Term
pseudomonas aeruginosa
Definition
EA associated with keratitis
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