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(MT3) Mitosis
BIO 202.01
13
Biology
Undergraduate 2
11/10/2012

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Cards

Term
Name the nine steps of mitosis in order.
Definition
G1, S, G2, prophase, prometaphase, metaphase, anaphase, telophase, cytokninesis
Term
What two things happens during interphase? 
Definition
Interphase consists of G1, S and G2. The cell grows and duplicates chromosomes during S (synthesis). Sister chromatids are formed. Centrosomes also duplicate and form asters.
Term
What two things happen in prophase?
Definition
Chromatin condense to visible chromosomes (with the help of proteins). Microtubules lengthen to form the mitotic spindle.
Term
What two things do chromosomes consist of?
Definition
DNA + proteins
Term
What three things happens in prometaphase?
Definition
The nucleur envelope breaks apart, the mitotic spindle invades the nucleur space, spindles attach to kinetochores on centromeres of sister chromatids.
Term
What three things happen in metaphase?
Definition
Sister chromatid align along the metaphase plate. Equal and opposite forces are applied to the sister chromatids. Unattached spindles overlap.
Term
What two things happens in anaphase?
Definition
Sister chromatids seperate and are pulled apart because of motor proteins disassembling the spindle within the chromosome, the unattached microtubules extend.
Term
What three things happens in telophase?
Definition
A nucleur envelope begins to form around the two nuclei, chromosomes  slightly unfold, microfilaments form a cleavage furrow, which will pinch the cells to separate them
Term
How is cytokinesis different in animal and plant cells?
Definition

In animal cells, the cell pinches with the help of microfilaments.

 

In plant cells, vesicles containing cell wall material align in the middle of the cell and form a new cell wall.

Term
Cells who do pass the G1 checkpoint do not divide (like many adult cells), what stage do they enter instead? What is another name for the G1 checkpoint?
Definition
G0 phase, G1 checkpoint = Restriction Point
Term
Where are the three major checkpoints in the cell cycle?
Definition
G1, G2, M
Term
What signals the cell to pass certain checkpoints? When are these signals active?
Definition
CDKS's (cell division kinases) phosphorylate other proteins to change their conformation and activity, CDK's are active when bound to a cyclin protein (it's like the fuel)
Term
MPF is an example of a cell division kinase. Name three of its purposes.
Definition
It is used to pass the G2 checkpoint and start mitosis, to break down the nucleur envelope and induce the separation of sister chromatids during anaphase.
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