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MSK
Important MSK stuff for Step 1
79
Medical
Graduate
06/07/2010

Additional Medical Flashcards

 


 

Cards

Term
Innervation of the intrinsic muscles of the hand
Definition
deep ulnar nerve
Term
innervation of the thenar muscles
Definition
Median n. (recurrent branch)
Term
Cytoskeletal element in intermediate jxns
Definition
actin (connect to cadherins)
Term
Layers of the epidermis (out -> in)
Definition
Stratum corneum
stratum lucidum
stratum granulosum
stratum spinosum
stratum basalis
Term
Muscles of the anterior compartment of the arm, action and innervation
Definition
3 flexors of the arm innervated by the musculocutaneous nerve:
biceps brachii: supinates and flexes the forearm
brachialis: flexes the forearm
coracobrachialis: flexes and adducts the arm
Term
Muscles of the posterior compartment of the arm, their action and their innervation
Definition
Triceps brachii, extends the forearm, innervated by the radial nerve
Term
Muscles of the anterior compartment of the forearm, their innervation and action
Definition
Pronators of the forearm and flexors of the forearm, wrist and fingers
Term
Type 1 muscle fibers
Definition
Slow twitch, red
Term
Type 2 muscle fibers
Definition
Fast twitch, whiet
Term
2nd most commone primary malignant bone tumor
Definition
Osteosarcoma
Term
onion-skin appearance of bone
Definition
Ewing sarcoma
Term
chromosomal abnormality a/w Ewing's sarcoma
Definition
11;22 translocation
Term
Ab a/w Sjogren's Syndrome
Definition
Ab to ribonucleoproteins
SS-A (Ro)
SS-B (La)
Term
dry mouth, dry eyes and arthritis
Definition
Sjogren's syndrome
Term
dry mouth, dry eyes, nasal and vaginal dryness, chronic bronchitis, reflux esophagitis
Definition
Sicca Syndrome
Term
Pencil in cup deformity
Definition
Psoriatic arthritis
Term
dactylitis
Definition
psoriatic arthritis
Term
sausage fingers
Definition
psoriatic arthritis
Term
HLA-B27
Definition
1. Ankylosing Spondylitis
2. Reiter's Sydrome
3. Psoriatic Arthritis
Term
HLA-DQ
Definition
SLE
Term
HLA-DR4
Definition
1. Rheumatoid Arth
2. SLE
3. DM 1
Term
ANA for SLE
Definition
Sensitive but not specific
Term
Anti-dsDNA for SLE
Definition
Specific but poor prognosis
Term
Anti-smith Ab for SLE
Definition
specific, but not prognostic
Term
Anti-smith Ab for SLE
Definition
specific, but not prognostic
Term
Anti-histone Ab for SLE
Definition
Drug-induced lupus
Term
Elevated serum ACE levels
Definition
Sarcoidosis
Term
Ab a/w dermato/polymyositis
Definition
ANA, anti-Jo-1
Term
progressive symmetric prox muscle weakness usually involving shoulder, but w/o a rash
Definition
polymyositis
Term
progressive symmetric prox muscle weakness usually involving shoulder w/ a heliotrope rash
Definition
dermatomyositis
Term
Gottron's papules
Definition
dermatomyositis
Term
paraneoplastic syndrome a/w:
lambert-eaton
Myesthenia gravis
Definition
SCLC
THymoma
Term
Anti-Scl-70 Ab
Definition
diffuse scleroderma
AKA anti-DNA topoisomerase I
Term
Anti-centromere Ab
Definition
CREST syndrome
Term
MC soft tissue tumor of childhood
Malignant or Benign?
Definition
Rhabdomyosarcoma
Malignant
Term
Macule
Definition
Flat discoloration < 1 cm
Term
patch
Definition
flat discoloration > 1 cm
Term
papule
Definition
elevated skin lesion < cm
Term
Plaque
Definition
elevated skin lesion > 1 cm
Term
vesicle
Definition
small fluid containing blister
Term
wheal
Definition
transient vesicle
Term
bulla
Definition
large fluid containing blister
Term
Keloid
Definition
irregular, raised lesion resulting from scar tissue hypertrophy.
Follows trauma to the skin, especially in Af. Ams
Term
Pustule
Definition
blister containing pus
Term
crust
Definition
dried exudates from vesicle, bulla or pustule
Term
hyperkaratosis
Definition
thickening of stratum corneum
Psoriasis
Term
parakaratosis
Definition
thickenig of stratum corneum w/ retention of nuclei
Psoriasis
Term
acantholysis
Definition
separation of epidermal cells
pemphigus vulgaris
Term
acanthosis
Definition
epidermal hyperplasia
Term
dermatitis
Definition
inflammation of the skin
Term
White painless plaques on the tongue that cannot be scrapped off and assoc. dz
Definition
Hairy Leukoplakia
specific for HIV
Term
anti-epithelial cell Ab
Definition
pemphigus vulgaris
IgG against desmosomes
Term
IgG against desmosomes
Definition
pemphigus vulgaris
Term
Nikolsky's sign
Definition
separation of dermis upon manual stroking of skin
positive in pemphigus vulgaris
Term
Difference b/w pemphigus vulgaris and bullous pemphigoid on IF
Definition
pemphigus vulgaris - throughout epidermis
bullous pemphigoid - liner IF
Term
IgG to hemidesmosomes
Definition
bullous pemphigoid
Term
diff. b/w pemphigus vulgaris and bullous pemphigoid on PE
Definition
bullous pemphigoid lacks oral involvement and negative Nikolsky's sign
Term
eosinophis w/i blisters
Definition
bullous pemphigoid
Term
dermatits herpetiformis
Definition
pruritic papules and vesicles on extensor surfaces.
A/w celiac dz
Term
erythema multiforme
Definition
macules, papules, vesicles and target lesions
Term
rash a/w HCV
Definition
lichen planus
Term
ulcerative red lesion
Definition
SSC of skin
Term
actinic keratosis
Definition
premalignant, small, rough, erythematous or brownish papules.
Term
hyperplasia of stratum spinosum
Definition
acanthosis nigricans
Term
herald patch followed by rash in Christmas tree distribution
Definition
pityriasis rosea
Term
Keratin Pearls on histology
Definition
SCC of skin
Term
rolled edges e/ ulcerated center
Definition
BCC
Term
histology: "Palisading" nuclei
Definition
BCC of skin
Term
S-100 tumor marker
Definition
Melanoma
Term
characteristic of melanoma that correlates w/ risk of metastasis
Definition
melanoma
Term
precursor to melanoma
Definition
dysplastic nevus
Term
MC injured structure in rotator cuff syndrome
Definition
supraspinatus tendon
Term
action of the supraspinatus
Definition
abductor of the arm
Term
Enthesitis
Definition
Ankylosiing Spondylitis
Inflam of the enthesis
Term
Rochitic Rosary
Definition
Rickets
Bony prominences along costochondral jxns
Term
Extra-spinal/pelvic manifestations of AS
Definition
1. MSK- enthesitis
2. Respiratory- pain at costochondral and costovertebral jxns causes hypoventilation (reduced chest expansion)
3. CV- ascending aortitis -> dilation of aortic ring and aortic insufficiency
4. Eye- anterior uviitis
Term
MC injured nerve of the leg
Definition
common tibial nerve (superficially located on later proximal lag near head of fibula)
Term
provides sensation b/w the 1st and 2nd toes
Definition
deep peroneal nerve
Term
Pain and bone deformity + hearing loss
Definition
Paget's dz of the bone
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