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Merkel's Cell
(Fine Touch) |
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L = Langerhan's Cell
CP = Cytoplasmic Process |
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L = Langerhan's Cell
CP = Cytoplasmic Process |
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Birbeck's Granules
(Found in Langerhan's Cells, function unclear) |
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Dermis
P: Papillary Layer (Loose connective tissue, Type I/III collagen, blood vessels, and thin elastic fibers)
R: Reticular Layer (Dense Irregular connective tissue, Type I Collagen, Thicker elastic fibers) *****NO RETICULAR FIBERS EVERYTHING IS A LIE***** |
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Stratum Spinosum of Epidermis (circle around Node of Bizzozero- thickened desmosome connections) |
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Bullous Pemphigoid (Damage to hemidesmosomes --> separation of epidermis from dermis) |
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C=Corneum
G=Granulosum
S=Spinosum
B=Basale
D=Dermis |
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Pemphigus Vulgaris
(Autoimmune destruction of desmosomes, separation of Stratum Spinosum cells from each other) |
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Definition
Keratin Pearls assoc. with Squamous Cell Carcinoma |
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Stratum Spinosum/Granulosum
KG: Keratohyalin Granules (Cys/His --> Fillagrin --> Aggregation of Keratin Tonafilaments)
Arrowheads: Lamellar Bodies (secrete lipids --> water barrier) |
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Stratum Lucidum
(As bottom of corneum, NEVER in thin skin, SOMETIMES in thick skin) |
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Malignant Melanoma Immunohistochemistry with Melan A Marker |
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Definition
A: Ext. Root Sheath
B: Hair
C: Int. Room Sheath
D: Matrix
E: Dermal Papilla
F: Sebaceous Gland
G: Arrector Pili Muscle |
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Definition
Hair Follicle Cross Section
A: Medulla of Hair
B: Hair Cortex
C: Hair Cuticle
D: Int. Root Sheath
E: Basement Membrane
F: Ext. Root Sheath
G: Dermis
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G: Sebaceous Gland
F: Hair Follicle |
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Eccrine Sweat Glands (merocrine secretion, all skin types)
A: Myoepithelial Cells
B: Duct
C: Secretory Portion |
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Definition
Eccrine Sweat Gland
A: Duct
B: Secretory Portion |
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Definition
Left side: Eccrine sweat gland
Right side: Apocrine (axilla and perineum only, secrete pheromones, opens into hair follicle)
***Both merocrine secretion!*** |
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Pacinian Corpuscle
-Found in deep dermis/hypodermis
-Sense pressure/vibration
*N = Nerves |
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Meisner's Corpuscle (Light touch)
Dermal Papillary layer |
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Cartilage...
1: Capsular Matrix (around a single chondrocyte), more GAGs less collagen fibers
2: Territorial Matrix (around isogenous group)
3: Interterritorial Matrix (Between isogenous groups), more fibers less GAGs
P: Perichondrium
DCT: Dense connective tissue
GC: Who the fuck knows? |
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Definition
Perichondrium
FL: Outer Fibrous layer (Fibroblasts, blood vessels, Type I collagen)
CL: Inner Cellular Layer (Chondrogenic cells)
CF: Collagen Fibers |
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A: Articular Cartilage
B: Bone
SZ: Superficial/Tangential Zone
IZ: Intermediate/transitional zone
DZ: Deep/radial Zone
CZ: Calcified Zone
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Definition
Fibrous Cartilage (Mostly Type 1 collagen)
*Arrows pointing to Isogenous Groups
*Note: Fibrous cartilage = ONLY interstitial growth because no perichondrium |
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Osteocyte
A: Canaliculus
B: Lamina |
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Bone
L: Lacuna
Arrows: Canaliculi |
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IB: Immature Bone
MB: Mature bone |
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