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MS Test II
N/A
464
Nursing
Undergraduate 3
10/26/2010

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Cards

Term
Inflammation of urethra
Definition
Urethritis
Term
Inflammation of bladder
Definition
cystitis
Term
Inflammation of kidney
Definition
Pyelonephritis
Term
What is acute pyelonephritis caused by?
Definition
Bacteria
Term
What is chronic pyelonephritis caused by?
Definition
Immune disorder
Term
What is the term for pyelonephritis caused by blood borne organisms?
Definition
Urosepsis (Systemic)
Term
What bacteria are the majority of UTIs caused by?
Definition
E. coli
Term
Contrast medium inserted into bladder and x-rays taken while voiding
Definition
Voiding cystourethography
Term
Dye is injected into veins and cleared by kidneys. Obstructions are identified. Xray of urinary tract as dye clears.
Definition
IVP Intraveneous pyelogram
Term
Scope in bladder - Same day surgery - Conscious sedation or general anesthesia used. Can biopsy tissue as well as visualize.
Definition
Cystoscopy
Term
Which diagnostic test for urinary tract problems is most likely to cause a systemic reaction?
Definition
Intraveneous pyelogram (IVP)
Term
What is a normal side effect of a cystoscopy? (used for porstate issues, calculi & tumors)
Definition
Bloody urine x 3 voids
Term
Increased Creatinine & BUN indicate what?
Definition
Acute Renal Failure (ARF)
Term
What question must you ask a patient going for an IVP?
Definition
Are you allergic to shellfish or Iodine?
Term
What side effects of IVP dye are patients likely to experience?
Definition
Flush sensation
Sudden onset of nausea
Metallic taste
Urge to void
Term
What must be checked frequently after an IVP regardless of allergic rxn? Why?
Definition
I&O
The dye is nephrotoxic
Term
Cheapest, most effect abx for UTI. Need to increase fluids and limit sun exposure.
Definition
Sulfonamides (trimethoprim-sulfamethoxazone (TMP-SMZ)) Bactrim, Septra, Gantrisin
Term
Long-term UTI treatment for people that can't tolerate other abx. High bladder level, but low serum blood level & turns urine brown. Both for Tx and prophylaxis.
Definition
Nitrofurantoin (Macrodantin, NegGram).
Urinary anti-infective (not abx)
Term
Which drug is this nursing teaching appropriate for?Take w/meals
Avoid milk (interfered with drug absorption)
Oral suspension stains teeth - rinse mouth c medication
1500-2000 cc intake
Void 1500 cc in 24 hr period.
Definition
Nitrofurantoin
Term
Urinary analgesic that stains urine red-orange. Can only use for first 24-48 hours. Symptomatic relief of pain, burning frequency and urgency (may stop people from seeking Tx when they need it)
Definition
Pyridium
Term
Sign of Pyridium toxicity
Definition
Jaundice
Term
What organ is Pyridium metabolized by?
Definition
Liver
Term
Normal vs. UTI I&O goals
Definition
Normal - 1500-2000 I&O
UTI - 2500-3000 I&O
Term
Rn teaching r/t UTI prevention
Definition
Void before & after sex
Keep urine acidic w/Cran juice & Vit C
Good hygiene
Void 2-4 hrs.
Drink 8-10 glasses fluids a day
Cotton underwear
Avoid bubble baths
Teach signs & symptoms of UTIsW
Term
What structural change occurs in the ureter when calculi are present?
Definition
Dilation (attempts to get around stone)
Term
What are the most common types of renal calculi?
Definition
Calcium phosphate & Oxalate
Term
When do renal calculi cause stones?
Definition
When they cause an obstruction
Term
Classic 3 Stones Sx
Definition
Sweaty
Spasms
Stone trauma
Term
Ureteral anti-spasmodics (3)
Definition
Ditropan
Pro-Banthine
Atropine
Term
Uric Acid Calculi Rx
Definition
Allopurinal
Sodium bicarbonate
Potassium citrate
Term
Prevention of future renal calculi Rx
Definition
Thiazide Diuretic (Dec. Ca++ in urine)
Term
Nuts, beer, colas, asparagus, fruits, green beans, tomatoes and tea should be avoided with which condition?
Definition
Oxalate calculi (contain oxalate)
Term
Beans, lentils, chocolate, cocoa, milk, flour and dried fruits should be avoided in what condition?
Definition
Calcium based renal calculi
Term
Organ meats, sardines, herring, venison, goose, salmon, and acidic foods should be avoided in what condition?
Definition
Uric acid composed calculi
Term
Green veggies, legumes, milk and rhubarb SHOULD be eaten in what condition? Why?
Definition
Uric acid based stones -
Increase pH
Term
What characteristic should dietary staples have for someone with struvite stones?
Definition
Acidic (decrease pH)
Term
Cheese, eggs, cranberries, plums, grapes, tomatoes, whole grains and prunes should be eaten in what condition?
Definition
Struvite stones
Term
Two Tx options for renal calculi too big to pass.
Definition
Lithotripsy (shock wave)
Nephrolithotomy (putting nephrostomy tube in)
Term
You have an order to flush a nephrostomy tube with 30cc BID. What is your priority action?
Definition
Clarify the order - the kidneys do not have the space to handle 30cc - 10cc MAX.
Term
Painless hematuria may be a sign of what?
Definition
Bladder cancer
Term
Intravesical instillation into the bladder is what type of treatment for bladder cancer?
Definition
Chemo
Term
When is radiation therapy done for bladder cancer?
Definition
Pre-surgery or Palliatively
Term
What does the term radical mean in regards to surgery?
Definition
Taking out more than just the intended organ.
Term
What is required of the patient prior to a cystectomy?
Definition
NPO & Bowel prep
Term
What other part of the anatomy is usually made into a synthetic bladder?
Definition
Ileum
Term
What does a Kock pouch require of a patient?
Definition
Pt. must In and out cath self q 2-4hrs
Term
What is the downside to an Indiana pouch?
Definition
Much bowel is needed for synthetic pouch.
Term
What characteristic do you expect to see in the urine of a patient with a synthetic bladder made of ileus?
Definition
Mucus in urine.
Term
This test evaluated filling patterns of bladder
Definition
Cystometrography
Term
What size catheter do we typically use for males and females?
Definition
Males - 16 Fr
Females 14 Fr
Term
Poor contraction of detrusor muscle
Definition
Functional urinary retention
Term
What are three causes of functional urinary retention?
Definition
Spinal Cord Injury
Drugs
Abd. or pelvic surgery
Term
What drugs cause functional bladder retention?
Definition
Anticholinergics eg
Atropine, Robinul, Pro-Banthine, Scopolamine (sleep aids, anti-histamines, allergy/cold meds nonsprescription)
Term
This occurs with 150-300 mL in bladder in normal people
Definition
Trigonal stimulation
Term
This occurs when the bladder has >400 mL in normal people
Definition
Parasympathetic reflex
Term
Bladder filling causes frequent spontaneous detrusor muscle contractions and involuntary bladder emptying
Definition
Spastic Bladder (neurogenic bladder)
Term
Your patient has a spastic bladder. What drug class do you expect to be prescribed? What side effects will you tell your patient they may experience?
Definition
Anti-cholinergics
Dry mouth, blurred vision, constipation
Term
Patient cannot perceive bladder fullness
Definition
Flaccid bladder
Term
What drug class would you expect your patient with a flaccid bladder to be prescribed?
Definition
Cholinergic drugs (Bethanechol)
Anticholinesterases (Neostigmine & Pyridostigmine)
Term
Antidote to cholinergic drugs
Definition
Atropine
Term
This type of bladder defect is seen in above S2 SCIs.
Definition
Spastic bladder
Term
This bladder defect is seen in S2-4 SCIs
Definition
Flaccid bladder
Term
Nerve destruction to detrusor muscle or external sphincter
Definition
Rhizotomy
Term
Which type of catheter has the highest risk of UTI?
Definition
Suprapubic
Term
Assessment of Urinary Incontinence acronym DIAPPERS stands for what?
Definition
Delirium/confusional states
Infection
Atrophic urethritis/vaginitis
Pharmaceuticals
Psychologic (esp depression)
Excessive excretion (CHF, hyperglycemia)
Restricted mobility
Stool impaction
Term
What bladder irritants should an RN instruct her incontinent patient to avoid?
Definition
Milk & milk products
Caffeine
Spicy foods
Alcohol
Citrus foods and juices
Term
This condition manifests in men as urinary obstruction (hesitancy, weak stream) and irritation (urgency, nocturia, dysuria)
Definition
Benign prostatic hyperplasia
Term
What are the characteristics of a malignant prostate?
Definition
Lumpy, hard & fixed
Term
This med shrinks the prostate
Definition
Finasteride (Proscar)
Term
Rx Inc. flow of urine in BPH
Definition
Tamsulosin (Flomax)
Term
Rx BPH to decrease smooth muscle contraction
Definition
Doxazosin (Cardura)
Term
Surgery to cut into prostate & bladder neck and widen urethra.
Definition
TUIP (TransUreteral Incision of Prostate)
Term
Surgery where obstructing prostate tissue is removed through urethra.
Definition
TURP (TransUreteral Resection of Prostate)
Term
What is the major post-op complication of a prostatectomy with a perineal approach?
Definition
Infection - Stools in incision
Term
These post-op issues: bleeding, clot retention, inability to void and UTIs are associated with what what surgery?
Definition
TransUrethral Resection of Prostate (TURP)
Term
What problems do men who get a TURP experience weeks later?
Definition
Incontinence
Impotence
Retrograde ejaculation (looks like pyuria)
Term
Do Continuous Bladder Irrigations (CBIs) need to be set up with an infusion pump? Why or why not?
Definition
No - Irrigation not infusion.
Term
What are the purposes of the three ports in a 3-way foley?
Definition
Balloon, Urination, Irrigation
Term
Your patient is in a lot of pain after a surgery for BPH and complains that his catheter is too tight and hurts. What is your priority action?
Definition
Explain to the patient that it can't be relaxed because of the risk of clots forming in the urethra if they get past the foley. Assess the need for pain meds and give as necessary.
Term
How do you keep accurate I&Os on a person receiving a CBI through a foley?
Definition
Subtract what you put in from what came out.
Term
What supportive devices can you give a patient who has had a perineal prostatectomy?
Definition
T-Binder or padded scrotal support
Term
When should post-perineal prostatectomy perform perineal sterile NS irrigations?
Definition
Before and after each bowel movement.
Term
What antigen is used to screen and stage prostate cancer?
Definition
PSA
Term
What is the normal value for PSA?
Definition
<4 ng/mL
Term
What are the top three treatments for prostate cancer?
Definition
Prostatectomy
Radiation
Hormone manipulation: Androgens (estrogens)
Term
What is the first manifestation of prostate cancer?
Definition
Bone pain in back & joints
Term
What are the late stage symptoms of prostate cancer?
Definition
Bowel & bladder dysfunction
Weight loss & fatigue
Term
What can happen if prostate cancer infiltrates the bone marrow?
Definition
Severe anemia & impaired immune function
Term
Your male client is experiencing urinary incontinence - what do you teach him to prevent this?
Definition
Kegel exercises
Term
What are acute & chronic pain usually r/t in prostate cancer?
Definition
Metastasis to spinal column
Term
What are the three main causes of impotence r/t prostate cancer?
Definition
Surgery
Hormonal Tx lowers libido
Low self esteem & fears
Term
After age 50, what are the prostate cancer screening recommendations?
Definition
DRE (digital rectal exam) & PSA testing every year
Term
What endocrine disorder can cause problems with urination? Why?
Definition
DM - neuropathies
Term
What % of breast cancer is experienced by males?
Definition
1%
Term
Constriction of foreskin so it cannot be retracted of glans penis
Definition
Phimosis
Term
Foreskin is tight & constricted and not able to cover glans penis entirely
Definition
Paraphimosis
Term
What is a nosocomial cause of paraphimosis?
Definition
Taking too long to put a catheter in
Term
What Tx may be indicated for paraphimosis?
Definition
Circumcision
Term
Involuntary sustained painful erection not associated with sexual arousal
Definition
Priapism
Term
Ischemia and fibrosis of erectile tissue with potential impotence may occur with this disorder of the penis.
Definition
Priapism
Term
Phimosis, HIV, HPV and exposure to UV light are all risk factors for what disease?
Definition
Cancer of the penis
Term
Three mainstay Txs for penis cancer
Definition
Amputation; partial amputation
Fluorouracil cream
Radiation or laser therapy
Term
Fluid in the scrotum
Definition
Hydrocele
Term
Mobile & painless cyst resulting from leakage of sperm due to trauma or infection
Definition
Spermatocele
Term
Dilation of vein in spermatic cord - no Tx unless fertility is a concern
Definition
Varicocele
Term
Inflammation of epididymus
Definition
Epididymitis
Term
Acute testicular inflammation caused by viral infection
Definition
Orchitis
Term
Acute testicular inflammation caused by viral infection
Definition
Orchitis
Term
Testicle is mobile and the spermatic cord twists cutting off blood supply.
Definition
Testicular torsion
Term
What may happen if testicular torsion is left untreated?
Definition
Necrosis, atrophy or abcess
Term
What is the more common form of cancer for younger men?
Definition
Testicular ca
Term
What is a significant diagnostic finding for testicular ca?
Definition
Enlargement of one teste without pain
Term
Top 3 Txs for testicular ca
Definition
Surgery - Orchiectomy
Radiation - External beam
Chemo - Bleomycin, etoposide & cisplatin
Term
How often should men perform TSEs?
Definition
1x/month
Term
50% of attempts at sexual activity failed is considered clinically relevant for what?
Definition
ED
Term
When can patients who have had a penile implant resume sexual activity?
Definition
After healing (usually 6-8 weeks)
Term
Normal Hgb & Hct for women
Definition
Hgb: 12-16
Hct: 38-47%
Term
Normal Hg & Hct for men
Definition
Hg: 13-18
Hct: 40-54%
Term
Hgb is closely related to Hct. What else can an abnormal Hct indicate?
Definition
Fluid issues: deficiency or excess
Term
Level of Hgb when multi-system symptoms happen?
Definition
<6
Term
Level of Hgb when the patient has palpitations, SOB & fatigue
Definition
6-10
Term
Mild anemia Hgb level
Definition
10-13
Term
Iron deficiency anemia (malnutrition)
Definition
Microcytic anemia
Term
Mal-absorption of Vit. B12/pernicious anemia can be due to dietary lack or lack of intrinsic factor
Definition
macrocytic anemia
Term
Folic acid deficiency anemia - Pregnancy, children, malnutrition
Definition
Megaloblastic anemia
Term
Consequences of sickle cell.
Definition
Hemolysis & ischemia
Term
What can you give to help patients experiencing a sickle cell crisis?
Definition
O2, H2O, rest, analgesics
Term
What type of genetic disorder is sickle cell?
Definition
Autosomal recessive
Term
What do patients experiences severe thalassemia need?
Definition
Blood transfusions
Term
What electrolyte imbalance do you need to worry about with hemolytic anemias?
Definition
Hyperkalemia
Term
Enzyme deficiency G6PD is a type of what?
Definition
Hemolytic anemia
Term
Severe burns, transfusion rxns, drugs, toxins and venoms can cause what?
Definition
Acquired hemolytic anemia
Term
Tx acquired hemolytic anemia
Definition
Blood transfusions, electrolytes, spleenectomy, folate, steroids
Term
Before giving a patient a blood transfusion, what do you need to ask them about pain wise?
Definition
Flank/back pain
Term
All blood cell counts are low
Definition
Pancytopenia
Term
Anemia r/t bone marrow depression/failure
Definition
Aplastic anemia
Term
What can suppress bone marrow and therefore cause aplastic anemia?
Definition
Chemo, viral infections, radiation
Term
What can we do for someone with aplastic anemia?
Definition
Blood transfusions, bone marrow transplants
Term
Who is a bone marrow transplant harder on, the donor or the receiver?
Definition
Donor
Term
Chemo agent used to reduce severe sickling in sickle cell anemia
Definition
Hydroxyurea
Term
What is the normal ratio of Hg:Hct?
Definition
1:3
Term
What level of Hg do we normally transfuse people at?
Definition
8 or less
Term
After transfusing someone who had a Hgb at 8 or less, what range would you expect them to get back to?
Definition
9, we don't transfuse back to normal range we get them out of the danger zone
Term
What happens to the RBCs when smoking?
Definition
CO binds to RBCs instead of O2 and render the RBC useless for perfusion
Term
What is the priority activity for someone who is very anemic?
Definition
Rest - stop/slow down if sxs
Term
How do we diagnose myelodysplastic syndrome (MDS)/ Leukemia
Definition
Bone Marrow Biopsy
Term
Your patient is being prescribed Procrit, why?
Definition
Anemia
Term
A shift to the left in patients with leukocytopenia may indicate what?
Definition
Recovery
Term
What lab values do you expect to be significantly higher than normal in your patient with polycythemia vera?
Definition
RBCs & Hct (Inc. blood viscosity)
Term
Excess erythropoietin or Inc. hypoxia
Definition
Secondary erythrocytosis
Term
Neoplastic stem cell disorder where RBCs are increased.
Definition
Primary erythrocytosis (polycythemia vera)
Term
Engorged vessels
Definition
plethora
Term
Your client has ruby red colored lower extremities, what condition do you suspect?
Definition
Polycythemia
Term
Should a patient with polycythemia have their legs elevated or dependent?
Definition
Elevated
Term
B-Cells are infected in Mononucleosis by what virus?
Definition
Epstein-Barr virus
Term
What is the incubation period for mono?
Definition
4-8 wks
Term
How long can mono last?
Definition
Up to 3 months
Term
How long is the acute phase of mono?
Definition
7-20 d
Term
ANC must be < than _______ for neutropenia
Definition
1500
Term
Normal ANC
Definition
>2200
Term
Life span of WBCs
Definition
1 day
Term
At what ANC are clients put in protective isolation?
Definition
<500
Term
Calculation of ANC
Definition
Segmented neutrophils +bands/100 x WBCs
Term
What is the most important step to take to prevent infection in individuals with neutropenia?
Definition
Make sure they maintain adequate hygiene
Term
Presence of malignant immature WBCs in bone marrow, circulation, liver, spleen and lymph nodes.
Definition
Leukemia
Term
What are the four types of leukemia?
Definition
AML
ALL
CML
CLL
Term
How do we determine what type of leukemia a patient has? How do we monitor the effects of treatment?
Definition
BM biopsy
Term
excessive proliferation of blast cells
Definition
leukocytosis
Term
What do patients with leukemia usually die from?
Definition
Internal hemorrhage & infection
Term
A patient's labs say that the WBC count is 200,000. What do you suspect?
Definition
Leukemia
Term
What labs do you expect to be low in a patient with leukemia?
Definition
RBCs, Plt, Neutrophils
Term
Which group of Leukemia patients has a higher successful cure rate, children or adults?
Definition
Children
Term
G-CSF (Granulocyte colony stimulating factor)
Definition
Neupogen (filgrastim)
Term
How often are leukemia patients kept in the hospital after chemo?
Definition
~1 month
Term
Decrease in renal function, increase in metabolism, increase in ICP and bone pain are often seen in what?
Definition
Infiltrate sxs of leukemia
Term
Type of leukemia for which no Tx is given until chemo in the late stage.
Definition
Chronic Lymphocytic Leukemia (CLL)
Term
Type of leukemia for which bone marrow transplants are given. CNS infiltrates.
Definition
Acute lymphocytic leukemia (ALL)
Term
Type of leukemia that has a terminal blast crisis (acute) phase and is treated with interferon, chemo and gleevec.
Definition
Chronic Myeloid Leukemia
Term
Proliferative type of leukemia treated c chemo.
Definition
Acute myeloid leukemia (ALL)
Term
You leukemia patient has a very supportive family. They have brought flowers, raw fruits & veggies and the patient's child, who is coughing and has a runny nose. What is your priority action?
Definition
Inform them of why these things are inappropriate and put your patient at risk.
Term
anti-ulcer coating drug
Definition
sucralfate
Term
Cancer of lymphoid tissues. Proliferation of lymphocytes, resident monocytes & macrophages and precursors.
Definition
Malignant lymphoma
Term
Two types of lymphoma
Definition
Hodgkin's and Non-Hodgkin's
Term
This type of lymphoma has no cure.
Definition
Indolent Non-Hodgkins
Term
This type of lymphoma is seen in 15-35 yo and >50. It has a 60-90% cure rate if diagnosed early.
Definition
Hodgkin's Lymphoma
Term
This type of lymphoma is seen in older adults and has a 30-60% cure rate if it is an aggressive lymphoma.
Definition
Non-Hodgkin's Lymphoma
Term
Type of lymphoma involving Reed-Sternberg cells. May be caused partially by Epstein-Barr virus and genetic factors.
Definition
Hodgkin's Lymphoma
Term
Lymphoma with GI symptoms like jaundice, bloody diarrhea and cramping as well as hemolytic anemia, ureteral obstruction and spinal cord compression.
Definition
Non-Hodgkin's Lymphoma
Term
Symptoms of all lymphoma
Definition
Swollen, painless lymph nodes
Persistant fever
Pruritis
Night sweats
Anemia
Fatigue
Malaise
Weight loss
Term
Possible side effect of chemo & radiation for lymphoma.
Definition
Permanent sterility
Term
Malignant disorder of plasma cells in which immature cells proliferate in BM, lymph nodes, spleen and kidneys
Definition
Multiple Myeloma
Term
What major systems does multiple myeloma affect?
Definition
Bones and Kidneys
Term
What lab values do you expect to see in a patient with multiple myeloma?
Definition
Hypercalcemia, Decreased blood components
Term
What happens to the bones in multiple myeloma?
Definition
Bone pain, eats away at bone and causes hypercalcemia. Decrease in bone density leading to pathological fractures and spinal cord compression
Term
What immunoglobulin affects the body systems negatively in multiple myeloma?
Definition
M-protein immunoglobulin (cancerous)
Term
What renal tubule damaging protein is found in the urine of multiple myeloma patients?
Definition
Bence Jones protein
Term
Rx Hypercalcemia
Definition
Calcitonin, bisphosphonates, furosemide, IV sodium or potassium phosphate, glucocorticoids, weight bearing.
Term
Type of WBC cancer without a cure
Definition
Multiple myeloma
Term
How long do patients with MM usually survive?
Definition
4-5 yrs, longer if indolent
Term
Type of ca with leukocytosis, anemia, risk for infection & bleeding.
Definition
Leukemia
Term
Type of ca with painlessly swollen lymph nodes
Definition
Lymphoma
Term
Type of ca with renal failure, hypercalcemia and bone pain w/pathological fractures
Definition
Multiple Myeloma
Term
Where are 30-40% of platelets stored?
Definition
Spleen
Term
Thrombocytopenia is defined at plt <_____
Definition
100,000
Term
Risk of spontaneous bleeding plt count
Definition
<20,000
Term
Half life plt
Definition
~10 d
Term
Normal bleeding time
Definition
2-9s
Term
Autoimmune destruction of plt by spleen.
Definition
Immune Thrombocytopenia Purpura (ITP)
Term
Microcirculation occlusion by clots from platelet aggregation leading to fragmented RBCs and hemolytic anemia
Definition
Thrombotic Thrombocytopenia Purpura (TTP)
Term
Platelet & immune complex cluping -> clots
Definition
Heparin-Induced Thrombocytopenia (HIT)
Term
Thrombin inhibitor
Definition
lepirudin (Refludan)
Term
Rx chemo-induced thrombocytopenia
Definition
oprelvekin (Neumega)
Term
How much does 1 unit of platelets inc. plt count by?
Definition
10,000
Term
At what plt count do we transfuse pts?
Definition
<10,000
Term
CNS Sx of bleeding
Definition
HA, visual changes, LOC changes & seizures
Term
In pt. with thrombocytopenia, hold puncture sites for ______min and ABG sites (arterial) for ______min.
Definition
3-5; 15-20
Term
Optimal heart beat
Definition
70bpm
Term
How long do you have to wait to re-inflate the cuff to get an accurate BP?
Definition
30s
Term
How much lower can you expect BP to be when sleeping?
Definition
20 mm
Term
Tissues most affected by chronic HTN.
Definition
Eyes, heart, vessels, brain & kidneys
Term
Dx HTN Intermittent or sustained systolic >____ or diastolic >_____
Definition
140; 90
Term
120-139 systolic BP is classified as what?
Definition
Pre-HTN
Term
How big does MAP have to be to perfuse kidneys & organs other than <3 & brain?
Definition
60
Term
MAP calculation
Definition
(Sys + 2Dias)/3
Term
What is a major contributor to high BP?
Definition
Cigarette smoking (Inc. BP, HR, O2 use and vasoconstricts)
Term
What nutrient helps decrease homocysteine levels?
Definition
Folic acid
Term
What do women have until menopause that protects them from coronary artery disease?
Definition
Estrogen
Term
This syndrome is characterized by apple shaped/abd obesity, inc. triglycerides, dec. HDLs, Inc BP & glucose, clotting tendency & inflammatory factors
Definition
Metabolic syndrome
Term
HTN with no identifiable cause
Definition
Primary HTN
Term
Nsg mgmt hypertensive emergency within minutes
Definition
Reduce BP by 25%
Term
What should BP be by 2-6 hrs in HTN emergency?
Definition
160/100
Term
HTN emergency BP
Definition
>240/130
Term
What is the usual cause of HTN emergency?
Definition
Pts stop taking their meds
Term
Malignant HTN is defined as DBP >____
Definition
120
Term
This drug is a direct acting vasodilator that works on arterioles and is used IV to lower BP rapidly in severe HTN episodes. Must be administered in small incremental doses.
Definition
Hydralazine
Term
What HTN drugs are contraindicated in asthmatics?
Definition
B1B2 blockers like Propranolol
Term
How do Ca++ channel blockers decrease heart rate?
Definition
Decrease contractility of heart by blocking calcium influx into cells.
Term
Major SE ACEi's
Definition
Cough
Term
Major electrolyte effects ACEi's
Definition
Hyperkalemia, Na+ excretion
Term
HTN med interrupts early on in RAAS w/o cough.
Definition
ARBs (sartans)
Term
Giant wheals of edema, tongue, glottis and pharynx are called ________ and must be immediately reported. SE of ACEis and ARBs
Definition
Angioedema
Term
Major cause of Tx failure r/t HTN
Definition
Lack of patient compliance (impotence, need for multiple appts)
Term
What can the body do to bypass/compensate for defective blood vessels?
Definition
Form collaterals
Term
When do manifestations of atherosclerosis appear?
Definition
75% lumen occluded
Term
Normal LDL, HDL, Cholesterol, Triglyceride, and Homocysteine levels
Definition
LDL <130
HDL >37 males >40 females
Cholesterol <200
Triglycerides <190
Homocysteine <17
Term
HDL:Cholesterol ideal & normal values
Definition
Ideal: 1:3
Normal 1:5
Term
1st line Rx hyperlipidemia
Definition
Statins
Term
SE to watch for of statins
Definition
Muscle pain/weakness (myopathy)
Urine changing to brown (toxicity)
Term
Drug used in combo w/statins. Can't use alone b/c high doses have lots of SE.
Definition
Nicotinic Acid (Niacin)
Term
Cholesterol lower drug that binds bile acids in intestine & dec. cholesterol producting in liver
Definition
Bile acid sequestrants (Questran, Colestid)
Term
Drug that lowers triglyceride levels and is used in combo therapy for high cholesterol.
Definition
Fibric acid derivatives (Lopid)
Term
ETOH goal for patients with HTN & Hyperlipidemia
Definition
Moderate - 2 drinks for males and 1 for females/day
Term
If chest pain is on and off what does that indicate?
Definition
When off <3 is getting O2 - less risk for necrosis
Term
If blood flow to the <3 is restored in _____ min, contractility is restored and cellular repair begins
Definition
20
Term
What different symptoms of angina do women have?
Definition
Back pain & indigestion
Nausea, SOB
Fatigue & weakness of shoulders & upper arms
Term
Upredictable angina caused by spasm (at night)
Definition
Prinzmental's
Term
Angina that increases with activity (workload of heart)
Definition
Stable angina
Term
Unpredictable angina that increases in frequency, severity and duration
Definition
Unstable angina
Term
Asymptomatic ischemia that occurs with activity or mental illness
Definition
Silent MI
Term
This type of angina is relieved by rest & nitrates
Definition
Stable angina
Term
Classic chest pain sequence
Definition
Activity - Pain - Rest - Relief
Term
What is the difference between Angina & MI?
Definition
Angina is only partial obstruction of vessel
Term
Women's MI risk factors
Definition
Oral contraceptives, smoking, stress from family/work roles, post menopausal lack of estrogen
Term
US used to Dx CAD
Definition
ECHO
Term
High risk Dx tool for CAD
Definition
Stress/Exercise ECG
Term
ECHO from inside for Dx CAD
Definition
TransEsophageal ECHO (TEE)
Term
Dx tool for CAD using dye
Definition
Angiography
Term
What is indicative of a positive ECG stress test?
Definition
1. Pt reports CP
2. ST Dec. 3 mm or more
3. Pt requests stopping due to fatigue, dysrhythmias or other sx.
Term
Serum Cardiac Markers Dx Angina
Definition
CK, CKMB, Troponins
Term
Blood flow reduced but not fully occluded.
Definition
Acute Coronary Syndrome (ACS)
Term
Condition in which cardiac markers are abnormal vs. normal.
Definition
Abnormal - AMI
Normal - Stable angina, ACS
Term
Which event has greater ST changes, ACS or AMI?
Definition
AMI
Term
How do we avoid tolerance to NTG?
Definition
Remove at night or whenever least likely to have an MI
Term
Best practice for applying Ntg patches
Definition
When you put one on, remove one!
Term
SE Nitrates
Definition
HA & HoTN
Term
Nitrate administration during acute attack.
Definition
Take 3 doses 5 min apart. If no relief or pain continues for 20 min, seek emergency assistance.
Term
Nsg priorities for patient in AMI
Definition
Baseline vitals & pain
O2
Nitro
Term
Analgesic & vasodilator
Definition
Morphine
Term
Slower acting angina Rx
Definition
B blockers
Term
Potent coronary dilators that block Ca++ channels
Definition
Verapamil
Diltiazem
NifedipineHow
Term
How soon does tpa need to be given after MI in order to be effective?
Definition
Within 6 hours
Term
What drug class prevents ventricular remodeling post MI
Definition
ACEi
Term
How long post MI does a patient need to be on strict bedrest?
Definition
12 hours then gradually inc. activity
Term
Normal O2 flow for post MI
Definition
2-5L/min
Term
Immediate nutrition recommendation post-MI
Definition
Small, frequent meals but NONE if going to cath lab
Term
Medical mgmt Rx MI
Definition
Morphine
Oxygen
Nitrates
Aspirin (MONA)
Term
ABCDE guidelines for mgmt stable angina
Definition
Aspirin & Anti-anginals
B-blockers & dec. BP
C - Decrease Cholesterol and cigarette smoking
D - Diet & manage DM
E - Education and exercise
Term
What risk do all revascularization procedures carry?
Definition
Restenosis
Term
PCR
Definition
Percutaneous coronary revascularization
Term
PTCA
Definition
Percutaneous Transluminal Balloon Angioplasty
Term
Appropriate nsg actions post PCR or PTCA
Definition
HOB flat & bedrest
Monitor & Tx CP
VS Q15 min
Look for bleeding and VS indicating a bleed.
Check peripheral pulses and examine scrotum/labia and underneath for blood (path of least resistance)
Term
Risk with ballooning or stenting vessels
Definition
Can make clot into embolism
Can rupture blood vessel
Term
Surgery where a vein or artery is used to create a new connection between aorta and coronary artery beyond obstruction
Definition
CABG
Term
What do surgeons induce during a CABG?
Definition
Hypothermia
Term
SA node stimulated HR
Definition
60-100
Term
AV node stimulated HR
Definition
40-60
Term
Purkinje fiber stimulated HR
Definition
15-40
Term
Controls # impulses that reach the ventricle
Definition
AV node
Term
What does an elevated ST wave in an EKG indicate?
Definition
Acute injury - Intervention must take place!
Term
Tx Sinus tach
Definition
B-blockers & Ca++ blockers
Term
Priority w/ tx sinus tach
Definition
Tx underlying cause
Term
Tx bradycardia (if symptomatic)
Definition
IV Atropine or pacemaker
Term
Disorganized atrial activity w/o discreet atrial contractions
Definition
A fib
Term
Lots of P waves to 1 QRS
Definition
A fib
Term
Risk in A-fib
Definition
Blood ppols & clots --> pulmonary/thrombo embolism
Term
Prophylaxis Rx A fib
Definition
Coumadin (warfarin)
Term
PVC within 4 hrs after MI, >6 PVCs/min, Couplet or triplet PVS and multifocal PVCs indicate what?
Definition
Myocardial irritability
Term
Life threatening dysrhythmias
Definition
V fib or V tach
Term
Priority nsg action in V-fib or V-tach
Definition
1. Check Pulse & LOC
2. If pulseless -> begin CPR
Term
If your patient wants to sit in a chair and is at risk for V fib or V tach - what is a prudent nsg action?
Definition
Put draw sheet underneath Pt in chair in case need to transfer to bed for CPR
Term
What position should your patient be in if have decreased CO? What should they have on them?
Definition
High Fowler's with O2
Term
Things to assess with decreased CO (SEVER acronym)
Definition
S/S
Etiology
Vitals
Electrolytes
Rx peak and trough
Term
Uncontrolled situation action
Definition
Defibrillation
Term
Controlled situation action
Definition
Cardioversion
Term
Your patient is in Vfib - what are your priority actions?
Definition
Call code blue
Start CPR
Prepare to assist with defibrillation
Term
Elective treatment for A fib, A flutter or Supraventricular tach
Definition
Cardioversion
Term
Risks associated with cardioversion
Definition
Burns from pads if out of date
Embolism risk for the next few weeks bc pushed clotty blood through stream
Term
After receiving cardioversion, what drug should a patient be on?
Definition
An anti-coagulant
Term
Inability of heart to pump sufficient blood to meet metabolic demands
Definition
heart failure
Term
Normal ejection fraction (%blood ejected with each beat)
Definition
55-65%
Term
Type of heart failure where heart is stiff, normal EF and heart can't relax and has impaired filling
Definition
Diastolic heart failure
Term
Type of heart failure where heart can't contract adequately and has impaired EF
Definition
Systolic HF
Term
Sx R sided diastolic HF
Definition
JVD, N/V
Term
Sx L sided diastolic HF
Definition
Crackles, SOB
Term
This type of HF is r/t ischemia and inflammation
Definition
Systolic HF
Term
This type of HF is related to dec. ventricular compliance
Definition
Diastolic HF
Term
Results of Systolic HF
Definition
Decreased CO & exercise tolerance, fatigue
Term
Both sides involved HF
Definition
Chronic HF
Term
R sided HF etiology
Definition
Pulm. HTN, acute & chronic pulm disease (BACKFLOW)
Term
L sided HF etiology
Definition
CAD, HTN
Term
Sx R Sided HF
Definition
Dependent edema,
JVD
Portal HTN & Ascites
Liver congestion
Congestion of peripheral tissues
GI tract congestion
N/V
Term
Sx L Sided HF
Definition
Pulmonary congestion & edema (DOE, crackles, SOB, cough, orthopnea, cyanosis, wheezes, S3) Dec. CO & Activity intolerance
Term
This marker is elevated in pt. with L ventricular dysfunction
Definition
BNP
Term
Acute onset HF
Definition
Massive MI
Term
Progressive deterioration of heart due to some underlying disease leads to what?
Definition
Chronic HF
Term
Low levels of what electrolyte enhance Digoxin effects and increase the risk of toxicity?
Definition
K+
Term
V-tach Rx
Definition
Amiodarone
Term
Digoxin antidote
Definition
Digibind
Term
Only effective Tx for end stage HF
Definition
<3 transplant
Term
Diet HF
Definition
1.5-2g Na+
Term
What should you teach the family of a patient with HF?
Definition
CPR
Term
What sort of activity regime should a HF pt have?
Definition
Moderate, progressive with tolerance
Term
Abnormal accumulation of fluid in alveoli of lung
Definition
Pulmonary edema
Term
Pulmonary edema is due to impairment of which ventricle?
Definition
Left
Term
What kind of cough does a person with pulmonary edema have?
Definition
Productive, frothy pink
Term
Drug given IV to Tx pulmonary edema
Definition
Aminophylline
Term
What must a patient with pulmonary edema have?
Definition
Intubation or CPAP (continuous positive airway pressure)
Term
Systemic inflammatory disease
Definition
rheumatic fever
Term
What does rheumatic fever lead to in 50% of cases?
Definition
Heart inflammation
Term
What valve does rheumatic heart disease affect most commonly?
Definition
Mitral
Term
Fever, joint pain, chest pain, pericardial friction rub, murmur, S3, S4 and cardiomegaly are manifestations of what?
Definition
Rheumatic Heart Disease
Term
Rx Rheumatic Heart Disease
Definition
PCN Full course
NSAIDs for joint pain
Corticosteroids for carditis
Term
Inflammation of endocardium
Definition
Endocarditis
Term
Fever 39.4C, Flu like symptoms, cough, SOB, joint pain, heart murmur (new or worsened) are signs of what?
Definition
Endocarditis
Term
Dx Endocarditis
Definition
ECHO
Blood cultures
Term
Rx Endocarditis
Definition
Abx for 2-8 wks
Term
Surgery Tx Endocarditis
Definition
Valve replacement
Term
Potential complication of endocarditis
Definition
Embolism (vegetation breaks off)
Term
Inflammation of heart muscle
Definition
Myocarditis
Term
Etiology Myocarditis
Definition
Radiation, chemo, drugs, poisons, infection
Term
Abx, corticosteroids, bed & emotional rest, O2 and hemodynamic monitoring are used to treat _______.
Definition
Myocarditis
Term
Inflammation of pericardium
Definition
Pericarditis
Term
Comfort measure for pericarditis
Definition
Sitting up and leaning forward may reduce pain
Term
S/S pericarditis
Definition
Pericardial friction rub
Dyspnea
Sinus tach
Low grade fever
CP aggravated w/breathing
Term
Complications pericarditis
Definition
Pericardial effusion
Cardiac tamponade
Chronic restrictive pericarditis
Term
Muffled heart sounds and distended neck veins characterize what condition?
Definition
Cardiac tamponade
Term
When a valve is not open or is closed completely
Definition
Stenosis
Term
When a valve doesn't close completely when it is supposed to and there is backflow
Definition
Regurgitation
Term
What happens when the ventricles remodel?
Definition
Dilate to adapt to inc. in volume and pressure
Term
Condition interfering with blood flow to and from heart involving valves of heart
Definition
Valvular Heart Disease
Term
Etiology Acute Valvular Heart Disease
Definition
Infection, MI
Term
Etiology Chronic Valvular Heart Disease
Definition
Rheumatic HD, aging
Term
What position can patients with valvular heart disease not be in?
Definition
Flat
Term
Tx valvular heart disease
Definition
valve replacement - mech or bio
Term
This type of valve required long-term coagulation therapy and bleeding precautions. Patient needs to come in routinely for INR
Definition
Mechanical valve
Term
This type of valve is less durable - 50% must be replaced in 15 yrs
Definition
Biological
Term
Changes in heart muscle
Definition
Cardiomyopathy
Term
Most common type of cardiomyopathy
Definition
Dilated
Term
Dilated cardiomyopathy is akin to what other disease we have talked about?
Definition
CHF
Term
Ventricle walls stiffen & lose flexibility
Definition
Restrictive cardiomyopathy
Term
Heart wall thickening
Definition
Hypertrophic cardiomyopathy
Term
Thickening, loss of elasticity and calcification of arterial walls
Definition
Arteriosclerosis
Term
A form of arteriosclerosis in which deposits of fat & fiber obstruct and harden arteries
Definition
Atherosclerosis
Term
Pain in calves to buttocks with activity; relieved by rest
Definition
Intermittent Claudication
Term
In intermittent claudication, patients have a burning sensation in the lower legs. When their legs are elevated the skin has ______ and when dependent the skin has ______.
Definition
Pallor; rubor
Term
What is impaired in the lower extremities in intermittent claudication?
Definition
Pulses, sensation, cap refill (PERFUSION)
Term
Complications of intermittent claudication
Definition
Gangrene, infection, amputation & hemorrhage
Term
Your patient is allergic to shellfish, what alternative do you offer the doctor to angiography?
Definition
Magnetic Resonance Angiography (Limited use)
Term
When is BP to lower extremities decreased (r/t intermittent claudication)?
Definition
With occlusions
Term
Your patient has atherosclerosis, why are they taking 81 mg ASA?
Definition
Anti-platelet aggregator. Platelets can stick to rough edges of plaque and form clot
Term
Rx removal of plaque
Definition
None
Term
Platelet inhibitor with vasodilator properties
Definition
cilostazol (Pletal)
Term
Rx decreases blood viscosity & Inc. RBC flexibility
Definition
pentoxyfylline (Trental)
Term
Procedure to remove plaque
Definition
Endarterectomy
Term
Where are endartarectomies most commonly performed?
Definition
Carotids
Term
5 Ps
Definition
Pain
Pallor
No Pulse
Paresthesia
Paralysis
Term
What angle do you want the patient's knees at that has impaired arterial tissue perfusion?
Definition
No angle! Hard to get around the bend
Term
Arterial issues you want the FOB _______ or ________. Venous issues you want the FOB _________.
Definition
Dependent or Horizontal; Elevated
Term
Why might you use a warm blanket and a bed cradle on your patient with arterial insufficiency?
Definition
Dilate arteries
Term
What activity can stimulate growth of collaterals?
Definition
Walking 30-45 min/day
Term
Your patient is determined to heal and walks 30-45 min every day to form collaterals. He states proudly that he continues walking even when it hurts. What is your response?
Definition
Stop and rest if pain (claudication starts); resume when pain subsides
Term
What extremities must receive special care in arterial insufficiency?
Definition
Feet! Treat like DM
Term
What kind of ulcers are surrounded by brown coloration?
Definition
Venous
Term
Occlusive vascular disease in which small and medium sized peripheral arteries become inflamed, spastic and thrombotic (Upper extremities usually)
Definition
Buerger's Disease (Thromboangitis obliterans)
Term
Episodes of intense vasospasm in small arteries in fingers and sometimes toes with coloration change.
Definition
Raynaud's Disease
Term
Colors of Raynaud's hands
Definition
White, Blue, Red
Term
Tx Raynaud's
Definition
No cure, relieve symptoms (avoid attacks)
Term
Centrifuging arms, decreasing stress, keeping extremities dependent and warm and good ideas for what diseases?
Definition
Raynaud's & Buerger's
Term
If damage to extremities is permanent, what must be done for Raynaud's and Buerger's patients?
Definition
Amputation
Term
Last resort Tx Buerger's disease
Definition
Sympathectomy or arterial bypass graft
Term
Drugs used in both Beurger's and Raynaud's diseases.
Definition
Ca++ blockers for relief of vasoconstriction.
Analgesics for pain
Pentoxifylline to decrease viscosity
Term
Thrombosis is treated by ________ whereas embolism is treated by _______.
Definition
Medications; Surgery
Term
What drug can you not use if patient has active bleeding, recent surgery, uncontrolled HTN or pregnancy?
Definition
Alteplase (tPA)
Term
tPA digests _____ matrix
Definition
Fibrin
Term
Oldest drug used for thrombolytic therapy is _____ and the antidote is ______
Definition
streptokinase; amicar
Term
Antidote tPA
Definition
Aminocaproic acid
Term
How soon after an embolism does an embolectomy have to be performed?
Definition
Within 4-6 hours
Term
Delays >____hrs after embolism result in increased risk of limb loss, resp. distress or ARF
Definition
12
Term
Inflammation of blood clot in vein wall
Definition
Thrombophlebitis
Term
In order to form a blood clot 2 of what 3 things are needed? (Virchow's triad)
Definition
Blood stasis
Inc. blood coagulability
Injury to vessel wall.
Term
Breaks down clots naturally
Definition
Fibrinogenase
Term
Palpaple cordy vein with redness and warmth near a PIV site is indicative of what?
Definition
Superficial thrombophlebitis
Term
Tx superficial thrombophlebitis
Definition
Warm compress
Elevation
Abx if infected
Term
In what patients do we prophylactically treat DVTs.
Definition
Pts >40 having surgery
Term
This test, if positive, indicates that there has recently been a clot that is being broken down due to the presence of excessive fibrin degradation products.
Definition
D-Dimer
Term
How long before surgery must a pt be off ASA?
Definition
2 wks
Term
tirofiban (Aggrastat), abciximab (ReoPro) and eptifibatide (Integrelin) are in what class?
Definition
GPIIB/IIIA receptor blockers (Anti-plt)
Term
Therapeutic level aPTT
Definition
1.5-2x normal 60-100s
Term
Heparin antidote
Definition
Protamine sulfate
Term
Normal aPTT
Definition
30-40s
Term
What lab can you monitor for a patient on enoxaparin (Lovenox)? What are the therapeutic values?
Definition
Anti-Factor Xa; 0.3-1.2
Term
Antidote Coumadin toxicity
Definition
Vit K (phytonadione (Mephyton))
Term
What two anticoagulants can you give at the same time? Why?
Definition
Hep & Coumadin - One works intrinsically, one works extrinsically and their affects don't add up. Used for transferring to PO meds
Term
Normal range of PT is _____; therapeutic range is _____
Definition
11-13; 18-26s (1.5-2x norm)
Term
Normal range INR _____; Therapeutic range _____
Definition
1; 2-3
Term
PT & INR are monitored for _________.
Definition
Coumadin
Term
Anti-factor Xa is monitored for ________.
Definition
LMWHs
Term
PTT is monitored fo _______.
Definition
Heparin
Term
This value of INR is desirable for someone with an artificial valve.
Definition
3-4
Term
PT levels should be checked how often after beginning Coumadin therapy?
Definition
QD x 5 days
2x/wk for 2 wks
q wk for 2 months
q3 months
Term
How many days should Heparin and Coumadin be overlapped?
Definition
4-5 days
Term
Non-surgical Tx DVTs
Definition
IV Heparin & strict bedrest until no tenderness and edema
Term
Surgical removal of thrombi from occluded vessel
Definition
Venous thrombectomy
Term
INsertion of a filtering device into inf. vena cava to capture venous thrombi and prevent pulmonary emboli in pts with recurrent DVTs.
Definition
Greenfield or Nitinol Filter
Term
Disorder involving stasis of blood in lower extremities as a result of obstruction & reflux of venous valves
Definition
Chronic venous insufficiency
Term
Leg edema, skin discoloration, fibrosis of SQ tissues and recurrent stasis ulcers result form this condition
Definition
Chronic venous insufficiency
Term
Silvadene cream, Zinc oxide, corticosteroid creams and broad spectrum abx/anti-fungal creams can be used on these.
Definition
Venous stasis ulcers
Term
Put these kinds of wet compresses on venous stasis ulcers 4x/day
Definition
NS or Burow's soln
Term
Nutrients v. important for healing patients with venous stasis ulcers
Definition
Vit A&C, Zinc
Term
Compression therapy device for venous stasis ulcers
Definition
Semi-rigid boots (Unna boots)
Term
This can occur with surgical removal of lymph nodes, scarring of lymph nodes by tumor or by a nematode worm (elephantitis)
Definition
Lymphedema
Term
Early sx lymphedema
Definition
Painless swelling tissues, soft & pitting edema
Term
Late sx lymphedema
Definition
Hardening/fibrosis: Brawny edema
Term
What complications can arise from lymphedema?
Definition
Lymphangitis & cellulitis
Term
dye injected into lymph to see flow
Definition
Lymphangiography
Term
Rx lymphedema
Definition
Diuretics; Dec. Na+ Intake
Term
Should you elevate or lower the lymphedematous limbs of your patient?
Definition
Elevate
Term
Surgery Tx lymphedema
Definition
Replacement of damaged lymph vessels
Skin, SQ removal and grafting (only 25% effective)
Term
This type of glomerulonephritis is caused by the antigen-antibody relationship with group A B-hemolytic streoptococcus.
Definition
Acute glomerulonephritis
Term
This type of glomerulonephritis is irreversible and progresses over weeks to months. IT is usually primary or secondary to a systemic disease like SLE or Goodpasture's.
Definition
Rapidly Progressive Glomerulonephritis
Term
This type of glomerulonephritis is a rare autoimmune condition that involved pulmonary hemorrhage.
Definition
Goodpasture's Syndrome
Term
In this type of glomerulonephritis there is no hematuria, serum lipids are increased, periorbital edema and risk for DVT or PE. (50% ESRD)
Definition
Nephrotic Syndrome
Term
In this type of glomerulonephritis the kidney's shrink until entire nephrons are lost. It is insidious until it progreses to RF. Slow, progressive. Common cause is diabetic nephropathy.
Definition
Chronic glomerulonephritis
Term
Leading cause of ESRD
Definition
Diabetic nephropathy
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