Term
| motor deficit as a result of cerebral ischemia due to intra-uterine injury; presents with delayed motor milestones and spastic [scissors] gait. |
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Definition
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Term
| damage to the cerebellum due to disease or alcohol abuse; presents with ataxia with a tendency of drifting towards the same side in which the damage is worse, dysdiadochokinesia, past-pointing and an intention tremor might be present. |
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Definition
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Term
| progressive neurological disorder seen more commonly in females and may run in families; presents with tremors of the hand that is apparent while performing voluntary movements such as eating and writing. |
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Definition
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Term
| inherited disease that causes progressive damage to the cerebellum, dorsal columns of the spinal cord and the heart; presents in the early twenties with ataxia, areflexia, loss of vibration sense and heart failure. |
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Definition
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Term
| inherited degenerative neural disease affecting the caudate nucleus and the putamen; presents with chorea, rigidity and decreased cognitive skills; CT scan and MRI might show the atrophy in the late stages. |
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Definition
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Term
| neoplastic plasma cell disease, more common in older men; presents with low back pain which is worse at night, fatigue; x-ray may show generalized osteopenia or multiple lytic lesions, skull x-ray has a rain-drops appearance, serum electrophoresis will show an M spike due to increased IgG levels, Bence Jones proteins will be found in the urine, hypercalcemia and a reversed albumin/globulin ratio will be present. |
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Definition
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Term
| chronic neurological disease affecting the substantia nigra and the basal ganglia in older people; presents with a shuffling gait, mask-like facies, pill-rolling tremor at rest, slowness of movement [bradykinesia] and micrographia [hand writing becomes progressively smaller and smaller]; MRI and CT scan of the brain is unremarkable. |
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Definition
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Term
| damage to the dorsal columns of the spinal cord caused by Treponema pallidum infection, part of tertiary syphilis; presents with ataxia, loss of vibration sense with a positive Romberg test; VDRL and TFA-abs tests are positive. |
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Definition
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Term
| vascular ischemia due to narrowing in the vertebral or basilar arteries, may be due to atherosclerosis; presents with diplopia, dizziness, dysphagia, ataxia, nystagmus or numbness; MRA will show the area of narrowing. |
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Definition
| Vertebrobasilar insufficiency: |
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Term
| genetic disease associated with defective copper transport resulting in the accumulation of excess copper accumulating in the brain, pancreas, testis, liver and heart and eyes; presents with decreased libido and pathognomonic Kayser-Fleischer rings in the periphery of the cornea; low levels of ceruloplasmin is diagnostic. |
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Definition
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