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Movement Disorders
Pathophysiology 2
14
Health Care
Graduate
12/02/2009

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Term
Peripheral Nervous System: Fasciculation
Definition
Spontaneous firing of single neurons: anterior horn cell fires, leading to mvt that isn't supposed to be there like twitching of lower eyelid. Will spontaneously resolve
Term
Peripheral Nervous System: Muscle cramps
Definition
Hundreds of anterior horn cells fire spontaneously. Mostly benign, but can be a disorder.
Term
Peripheral nervous system: Periodic Limb movement disorder
Definition
Frequent kicking of leg in sleep. Disrupts sleep.
Term
Movement disorders with voluntary control
Definition
Ticks, Turret's, Restless leg syndrome
Have to do them to relieve tension, borders on OCD.
Term
Movement disorders with voluntary control: TIck
Definition
Facial and neck gestures that come when nervous. Have to do them to relieve tension. Involves nerves of the brachial plexus region. ALso compulsion to do things- like poke eyeball out.
Term
Movement disorders with voluntary control: Turret's
Definition
A severe case of tick. One type is just movement. One type is voluntary mvt plus swearing.
Term
Movement disorders with voluntary control: restless leg syndrome
Definition
Esp at night. Correlated with the action of iron in dopamine system. Can arise from iron xu.
Term
Central nervous system: Tremors: Types
Definition
Physiologic tremor
Withdrawal tremor
Essential tremor
Tremor of parkinson's
Term
Central nervous system: Tremors: Physiologic tremor
Definition
Most people exhibit a fine. rapid tremor with outstretched hands. In general, tremor may be exaggerated by stress, anxiety, fatigue, metabolic derangement (withdrawal, thyrotoxicosis, drugs(caffeine, other phosphodiesterase inhibitors, b-adrenergic agonists, cortico steroids), hypothyroidism
Term
Central nervous system: Tremors: Withdrawal tremor
Definition
On chronic hypnotic sedatives or some stimulants with sudden withdrawal there's sudden intense sympathetic activation that causes tremors and even seizures.
Term
Central nervous system: Tremors: Essential tremor
Definition
Common. Sometimes sporadic. Starts young. Starts unilateral, then becomes bilateral.
Postural: worse when trying to do something. Can affect vocal chords.
Term
Central nervous system: Tremors: Essential tremor causes
Definition
Genetic mutation. Degeneration in baso-ganglion , extra pyramidal motor system which are the circuitry of motor movement. Lesions in different parts o baso ganglion system cause either essential tremor or Parkinson's.
Term
Central nervous system: Tremors: Essential tremor treatment
Definition
Implanted electrical leads in brain abort tremors. Invasive but not very destructive to brain.
Term
Central nervous system: Tremors: Tremor of Parkinson's
Definition
Resting tremor. Unilateral. GOes away when moving. Spares the vocal chords.
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