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More RNA Viruses
(-) ss and (-) ds
65
Biology
Graduate
04/24/2014

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Cards

Term

Which of the following virus(es) is/are ds RNA. 

Arenavirus

Reovirus

Orthomyxovirus

Paramyxovirus

Bunyavirus

Filovirus

Rhabdoviurs

Definition
Reovirus
Term

Are the following viruses negative or positive?

Arenavirus

Reovirus

Orthomyxovirus

Paramyxovirus

Bunyavirus

Filovirus

Rhabdoviurs

Definition
negative ss and ds (reovirus)
Term

Which of the following viruses have envelope? 

Arenavirus

Reovirus

Orthomyxovirus

Paramyxovirus

Bunyavirus

Filovirus

Rhabdoviurs

Definition
All, except for Reovirus
Term
Causative Agent of Hemorrhagic Fever Virus
Definition
Arenavirus
Term
Causative agent of Lymphocytic Choriomeningitis Virus.
Definition
Arenavirus
Term
Causative agent of rodent-borne disease.
Definition
Arenavirus
Term
Causative agent of Influenza A
Definition
Orthomyxovirus
Term
Influenza A causes what disease?
Definition
Flu
Term
How many segments is the (-) ss RNA of Influenza A?
Definition
8
Term
Influenza A attacks what part of the body?
Definition
Respiratory tract
Term
Influenza A is tranmsitted via what route?
Definition
Peron to person
Term
What animals can you find Inflenza?
Definition

Birds

Pigs

Whales

Horse

Seals

Term
T/F: The (-) ss RNA in 8 segments is the central idea to understaning Influenza A.
Definition
True
Term
What is the function of segment 4 of the (-) ss RNA in Influenza A?
Definition
Hemagglutinin (HA), a sticky substanc, that binds to mucoproteins of the cell surface.
Term
What is the function of segment 6 of the (-) ss RNA in Influenza A?
Definition
Neuraminidase (NA). It reverse Hemagglutinin binding by cleaving nuraminic acid groups. This releases the virus.
Term
T/F: 8 segments of the (-) ss RNA can recombine if there is a mixed infecion, but not homologous recombination within a segment.
Definition
True
Term
What are the 5 requirements when naming influenza?
Definition

Type of influenza (eg. A, B, C)

Where first isolated (place)

Number of the isolate

year of appearance

Ha and NA type

 

Ex: A/Singapore/6/86 (H1N1)

 

Term
How many types of hemagglutinin (HA) are available?
Definition
17
Term
How many types of Neuraminidase (NA) are available?
Definition
9
Term

Define Drift

 

Definition
Small changes in protein. This is a year by year change.
Term
Define Shift
Definition
Major chain a proteins that lead to new subtype. This occurs by the decade.
Term
T/F: Reye's syndrome causes an increase in pressure on the brain.
Definition
True.
Term
T/F: For Reye's Syndrome, you can use salicylates with a viral infection.
Definition
False
Term
Causative agent of Measles, Mumps, Respiratory Syncytial Virus, Parainfluenza.
Definition
Paramyxoviurs
Term
T/F: Paramyxovirus is the cause of childhood illness.
Definition
True
Term
Who are the hosts for Measles?
Definition
Humans are the only host
Term
T/F: Measles has 3 serotype.
Definition
False. Only 1
Term
What is the transmission route for Measles?
Definition
Spread by droplets
Term
T/F: Measles rash is spread from bottom to the top of the body.
Definition
False. From top to bottom
Term
Measles invades which part(s) of the body?
Definition
Respiratory epithelium and nasopharynx
Term
What is the KEY thing to look for in a patient with Measles.
Definition
Koplik's spotsin the mouth
Term
MMR (Measles, Mumps, Rubella) Adverse reactions
Definition

Fever

Rash

Joint symptosm

Thrombocytopenia

Parotitis

Deafness

Encephalopathy

Term
What is the obvious symptoms of Mumps?
Definition
Parotitis
Term
The most common cause of bronchiolitis and pneumonia in infants is
Definition
Respiratory Syncetial Virus
Term
T/F: Resipratory syncetial virus can recur throughout life, producing a severe cold.
Definition
True
Term
T/F: Resipratory syncetial virus in prevalent in the spring.
Definition
False. Winter
Term
Resipratory syncetial virus is notable for its production of
Definition
Cell Globs (Syncytia)
Term
Are there any vaccine for Respiratory Syncetial Virus and Parainfluenza?
Definition
No.
Term
T/F: Handwashing is the best supporttive treatment for Respiratory Syncetial Virus.
Definition
True
Term
Parainfluenza is originally known as
Definition
Influenza D
Term
T/F: Parainfluenza has 4 serotypes.
Definition
True
Term
T/F: Parainfluenza forms syncytia.
Definition
True
Term
T/F: Second to respiratory Syncetial Virus, Parainfluenza causes lower respiratory diseas in adult.
Definition
False. In young children
Term
What is/are symptom(s) of Parainfluenza?
Definition

Usually cold-like symptoms

Croup

Term
What protein is the major factor for Parainfluenza?
Definition
F (fusion) Protein
Term
T/F: Treatment is "supportive" for both Repiratory Syncetial Virus and Parainfluenza.
Definition
True
Term
Cauative Agent of LaCrosses ecnephalitis virus, Hanta virus, Crimean-Congo Hemorrhagic virus, and Rift Valley Fever virus.
Definition
Bunyavirus
Term
Causative agent of Rabies
Definition
Rhabdovirus
Term
Rabies is transmitted via
Definition

Animal bites (dog, bat, skunk)

Inhalation form

Tissue transplant

Term
If rabies is untreated, what is the percent of mortality?
Definition
nearly 100%
Term
T/F: Rabies vaccine can be given after infection and after nurological symptoms appear.
Definition
False. Rabies vaccine can be given after infection, but not after nurological symptoms appear.
Term
What are the 5 phases of rabies infection?
Definition

Incubation

Prodrome

Neurlogic

Coma

Death

Term
What are the symtoms of "Prodrome Phase" in an infected patient with rabies?
Definition

Fever

headache

nausea

lethargy

Term
What are the symtoms of "Neurologic Phase" in an infected patient with rabies?
Definition

Hydrophobia

Hyperactivity

Anxiety

 

Term
What are the symtoms of "Coma Phase" in an infected patient with rabies.
Definition

Cardiac arrest

Hypoventilation

Term
What are 3 things a physcian should look for when diagnosising a patient for Rabies.
Definition

Evidence of contact with a suspicous animal

Symptoms

Presence of Negril Bodies

Term
Where should a physician look to find Negril bodies in a patient with infected by rabies?
Definition

Cytoplasmic inclusion bodies in brain tissue.

Examine pyramidal cells of the hyppocampus.

Term
T/F: Negril bodies are Toll-like Receptor 3 with RNA and protiens of rabies.
Definition
True
Term
Causative agent of Hemorrhagic Fever Virus
Definition
Filovirus
Term
T/F: Filovirus requires contact with an infected person or animal.
Definition
True
Term
T/F: Reoviurs has ss RNA
Definition
False. ds RNA
Term
How many segments of ds RNA does Reovirus has?
Definition
10-12 segments
Term
T/F: Reoviurs do not have an envelope.
Definition
True
Term
T/F: Reovirus has virion.
Definition
True
Term
Reovirus casues what disease(s)
Definition

Respiratiroy

Enteric

Orphan

Milid URT illness

GI illness

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