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Molecules and Cells Exam 3
key terms
39
Biology
Undergraduate 1
03/25/2012

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Term
phosphorylation
Definition
addition of a phosphate group to a substrate
(can activate or deactivate)
Term
cellular respiration steps
Definition
glycolysis
pyruvate processing
citric acid cycle
electron transport and chemiosmosis
Term
glycolysis
Definition
one molecule of glucose is broken into two molecules of three-carbon compound pyruvate
2 ATP molecules are produced from ADP and one molecule of NAD+ is reduced to form NADH
Term
pyruvate processing
Definition
pyruvate is processed to form acetyl-CoA
another molecule of NADH is produced
Term
citric acid cycle
Definition
acetyl-CoA is oxidized to two molecules of CO2
more ATP and NADH are produced and FAD is reduced for form another electron carrier, FADH2
Term
electron transport and chemiosmosis
Definition
electrons from NADH and FADH2 move through a series of proteins called an electron transport chain
potential energy released during these redox reactions is used to create a proton gradient across a membrane
ensuing flow of protons back across membrane is used to make ATP (25)
Term
substrate-level phosphorylation
Definition
phosphate group from intermediate substrate + ADP -> ATP
used in glycolysis and citric acid cycle
Term
PFKase
Definition
catalyzes one of early reactions of glycolysis
inhibited allosterically by ATP
Term
overall respiration reaction
Definition
C6H12O6 + 6O2 -> 6CO2 + 6H2O + energy
Term
fermentation
Definition
metabolic pathway that regenerates NAD+ from NADH stockpiles, allowing glycolysis to continue making ATP in absence of oxygen (2ATP)
Term
cells' 2 fundamental requirements
Definition
energy and carbon
Term
hierarchy for ATP production
Definition
carbohydrates, then fats, and finally proteins
Term
photosynthesis reaction
Definition
6CO2 + 12H2O + light energy -> C6H12O6 + 6O2 + 6H2O
Term
light-dependent reactions
Definition
produce O2 from H2O (photosynthesis)
Term
Calvin cycle
Definition
reduces carbon dioxide to produce sugar
Term
photosynthesis direct function
Definition
converts electromagnetic energy in form of sunlight into chemical energy in C-C and C-H bonds of sugar
Term
classes of pigments in plant leaves
Definition
chlorophylls and carotenoids
Term
chlorophylls
Definition
absorb blue and red light and transmit green light
Term
carotenoids
Definition
absorb blue and green light and transmit yellow, orange, or red light
Term
chlorophyll parts
Definition
long tail made of isoprene subunits
head consisting of a large ring structure
Term
elements of a photosystem
Definition
antenna complex
reaction center
Term
mitosis and cytokinesis 3 key events
Definition
growth
wound repair
reproduction
Term
prophase
Definition
chromosomes condense into compact structures
formation of spindle apparatus
spindles move to opposite sides
Term
prometaphase
Definition
nucleolus disappears, nuclear envelope disintegrates
kinetochore microtubules attach to sister chromatids
chromosomes begin to align
Term
metaphase
Definition
centrosomes reach poles of cell
chromosomes align along metaphase plate
Term
anaphase
Definition
centromeres split
kinetochore microtubules shorten
sister chromatids move to opposite poles
Term
telophase
Definition
nuclear envelope begins to form around each chromosome set
spindle apparatus disintegrates
chromosomes begin to de-condense
Term
MPF subunits
Definition
protein kinase- enzyme that catalyzes transfer of a phosphate group from ATP to a target protein (cyclin-dependent kinase)
cyclin- regulatory protein
Term
G1 checkpoint criteria
Definition
cell size is adequate
nutrients are sufficient
social signals are present
DNA is undamaged
Term
G2 checkpoint criteria
Definition
chromosomes have replicated successfully
DNA is undamaged
activated MPF is present
Term
metaphase checkpoint
Definition
all chromosomes are attached to spindle apparatus
Term
metaphase checkpoint
Definition
all chromosomes are attached to spindle apparatus
Term
2 types of cancer cell defects
Definition
defects that make proteins required for cell growth active when they shouldn't be (proto-oncogene -> oncogene)
defects that prevent tumor suppressor genes from shutting down cell cycle
Term
principle of segregation
Definition
two members of each gene pair must segregate into different gamete cells during formation of egg and sperm in parents
Term
principle of independent assortment
Definition
alleles of different genes are transmitted independently of one another
Term
polymorphic
Definition
>2 distinct phenotypes in population due to multiple allelism
Term
quantitative traits
Definition
fall into continuum
Term
polygenic inheritance
Definition
many genes each have small contribution to value of a quantitative trait
Term
incomplete dominance
Definition
having one copy of allele is sufficient to give partial/weak coloration
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