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addition of a functional gene to produce a therapeutic protein for treatment of a disease |
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single stranded oligonucleotides (DNA) that form triplex structure with double stranded DNA and block its transcription |
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Definition
double stranded oligonucleotides (DNA) that bind to nuclear transcription factor and inhibit gene transcription |
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Definition
single stranded oligonucleotides (DNA or RNA) that bind to complementary mRNA and inhibit translation |
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Definition
RNA interference inhibiting translation of mRNA to protein by siRNA (small interfering double stranded RNA binding to complementary mRNA) or shRNA (short hairpen RNA transcribed from DNA) |
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micro RNA is non-coding double stranded RNA binding to 3'UTR of target mRNA and inhibiting its expression |
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RNA molecules that cut specific RNA substrate |
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Definition
single stranded or double stranded oligonucleotides that bind to specific proteins and alter their function |
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