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Definition
| process by which gene expression is controlled in response to external or internal signals |
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Definition
control of synthesis of several proteins by a single regulatory element
prokaryotes: the protein are usually translated from a single mRNA molecule |
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| regulation of gene expression in which mRNA is not synthesized until a repressor is removed from the DNA of the gene |
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| a protein that gins specifically to a regulatory sequence adjacent to a gene and blocks transcription of the gene |
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| transcription of a gene, or group of genes, only in the presence of an inducer molecule |
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| small molecule that inactivates a repressor by binding to it and thereby altering the ability to bind to the operator |
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| repressible transcription |
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Definition
| a regulatory process in which a gene is temporarily rendered unable to be transcribed |
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Definition
| protein converted to a repressor by binding with a particular molecule |
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Definition
| a small molecule that binds with a aporepressor to create a functional repressor molecule |
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| transcriptional activator protein |
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Definition
| protein that turns transcription on |
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Definition
| the protein product of a gene regulates its own transcription |
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| required for the entrance of lactose into the cell |
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Definition
| constant synthesis, with or without an inducer |
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| mutation that only effects the expression of only those genes on the same DNA molecule |
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| regulatory region in the DNA that interacts with a specific repressor protein in controlling the transcription of adjacent structural genes |
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Definition
| a DNA sequence at which RNA polymerase finds and initiates transcription |
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Definition
| collection of adjacent structural genes regulated by an operator and a repressor |
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Definition
| cyclic AMP and CAP protein; the complex is needed to transcription of certain operons |
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Definition
| a regulatory base sequence near the beginning of an mPNA molecule at which transcription can be terminated; when an attenuator is present, it precedes the coding sequences |
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Definition
| 14 amino acids with trp codons |
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Definition
| a 5' RNA leader sequence that, according to whether it is bound with a small molecule, can adopt either of two configurations - one permits transcription and the other that terminates |
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Definition
| encode essential metabolic enzymes or cellular components and are expressed constituatively at relatively low levels in the gene |
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Definition
| contains the genetic information to translate only a single protein |
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Definition
base sequence that increases the rate of of transcription of nearby genes, does not need to be adjacent to the gene, independent of orientation -- enable genes to be transcribed ONLY when prper transcriptional activators are present, many can control one gene |
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Term
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Definition
| short nucleotide sequences that are targets for DNA-binding proteins, once recruited to the site - pormote assembl of large protein complexes that precent transcription of those silenced genes |
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Definition
| aggregate of protein factors that combines with the promoter region of a gene to initiate transcription |
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Definition
| mechanism by which enhancers that are distant from the immediate proximity of a promoter can still regulate transcription, the enhancer and promoter come into indirect contact by means of looping out the DNA - physical interaction intiates transcription |
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Term
| basal transcription factors |
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Definition
| protines in the transcription comple that are widely used in the transcription of many different genes, highly conserved in eukaryotes |
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