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-Bacteriphage particles are pieces of DNA or RNA surrounded by protective proteins -icosahedra have 20 sides and 12 vertices or variations |
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-have coat proteins coating the viral nucleic acid helix -other coats protect a dsDNA core, attached to a proteinaceous tail (T4) or without tail fibers (lamda) |
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-have dsDNA, ssDNA, dsRNA, and ssRNA -can be linear or circular -some are even segmented with one segment per one or two genes -nonsegmented the whole viral genome serves as an operon |
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many small viruses have overlapping genes--gene within a gene in another reading from -a few codons from one gene being shared in a different reading frame |
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-you can synchronously infect a batch of bacteria with a batch of virions and each stage of the infection cycle will occur at the same time with all the bacteria in the culture -latent period has a steady number of infected cells, followed by a big increase in infected cells after the new virions are released to infect other cells--one-step growth curve |
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-host cells are starved and the viral sequence inserts itself into the host genome (a prophage) and is released |
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-surrouned by a lipid envelope with viral glycoproteins which recognizes a specific protein on the target host cell membrane -others are "naked" with only protein capsid no envelope |
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-have both RNA and DNA phases in their infection cycle -After entry into the cell, the genome is copied into double stranded DNA by a few molecules of reverse transcriptase that the virus caries in its capsid |
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-has LTRs (long terminal repeats) at each and three doing units in between |
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-long terminal repeats -three functions: promoter, enhancer, transcription terminator -gag, pol and env are expressed as polyprotein that is cut into functional and structural proteins |
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-satellite viruses are molecular parasites on plant viruses; code for their own coat protein but nothing else and are dependent upon their helper virus |
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-Satellite RNAs don't even code for their own coat protein and are encapsulated with the helper virus coat protein -also dependent upon the helper virus for replication |
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-smallest independent pathogen -360 bp of circular ssRNA and depending on the host's ddRNA polymerase (transcriptase) for their replication still need no helper virus |
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small circular ssRNA like viroids but are dependent on a helper virus for replication -hepatitis delta virus -rolling replication, producing a concatomer RNA |
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-coded for by one of our own genes -mutated for PrPsc predisposes one to Creutzfeldt-Jakob disease -power to induce other PrPsc or even PrPc proteins to take one that same perverted, pathogenic structure |
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-mobile element which have a DNA intermediate as they transpose from one location (donor) to the other (recipient) in the genome -if a copy is left behind it is "replicative"; if not then "conservative" |
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-mobile elements which have an RNA intermediate as they transpose -depend on normal cellular transcription to produce the RNA intermediate which is reverse transcribed by RT to produce dsDNA which is integrated by retroelement integrase into the recipient DNA |
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-can be carried by transposons, effect the integration of the transposon -single transposon is caused in insertion sequence while a composite transposon comprises a gene |
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