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molecular bio
exam 2: Transcription and translation
9
Biology
Undergraduate 2
10/16/2008

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Term
Central Dogma
Definition
Flow of information from DNA (gene) to RNA (transcriptone) to protein (proteome). DNA to hnRNA to mRNA to protein: Gene has to be able to produce RNA. Genes dont produce a functional RNA.
Term
hnRNA
Definition
Heterogeneous nuclear RNA. Large unprocessed molecule that gets processed to make RNA. Splices out entrons, adds poly tail and 5' cap. 5'cap allows molecules to leave nucleus.
Term
rRNA (Other Types of RNA)
Definition
Ribosomal RNA produces ribosomes, not proteins.
Term
tRNA (Other Types of RNA)
Definition
Translation, no proteins.
Term
snRNA (Other Types of RNA)
Definition
Small nuclear RNA (snoRNA) final product, processes other RNA molecules (no proteins). Removes entrons in a spliceosome.
Term
miRNA (Other Types of RNA)
Definition
MicroRNA regulates expression of other genes-monitors translation.
Term
xistRNA (Other Types of RNA)
Definition
Large RNA molecules regulate transcription. Plays role in x chromosome activation.
Term
Reverse Transcriptase (RNA to DNA)
Definition
Used by retroviruses. Used in telomerase.
Term
Cis DNA Elements
Definition
promoter, enhancer, silencer, insulator, etc.
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