Term
|
Definition
| First level of organization is wrapped around nucleosome. |
|
|
Term
|
Definition
| Group of histone proteins. Basic charge and DNA has negative charge so it can wrap around it. Contains 2 copies of each 4 histones. Each loop DNA around histone has 83 base pairs. Always 2 loops of DNA (166 total base pairs). ~150 base pairs there is another nucleosome. Beads on a string analogy. |
|
|
Term
|
Definition
| (H2a, H2b, H3, H4). H1: 11nm beads on string structure and coiling it(not part of nucleosome). Small, compact, basic proteins, with little tails. Allows for easy interaction. |
|
|
Term
|
Definition
| DNA between nucleosomes, which varies in length within a chromosome. |
|
|
Term
|
Definition
| Not part of nucleosome. Sits in linker region and crosslinks 2 adjacent nucleosomes. Super coils 11nm beads into 30nm beads. Helical arrangement. |
|
|
Term
|
Definition
| 6 nucleosomes per group. 2 loops of DNA. Linker(H1) pulls in adjacent nucleosomes to form solenoid. Diameter 30nm, varies slightly because linker DNA varies. |
|
|
Term
|
Definition
| Second level of packaging. |
|
|
Term
|
Definition
| Run down spine that runs down length of chromosomes to allow loops to attach to it. Loops attach to it. DNA before cell divides(non dividing cell). When cell divides they crunch DNA). Create chromosomal loops. Transcribing gene right on chromosomal loop when transcribe. |
|
|
Term
|
Definition
| Tightly packed and not transcribed. |
|
|
Term
|
Definition
| "Puffs" of transcribed DNA. Short region of DNA. Wraps on bead on a string structure. Different regions based on stage of transcription. |
|
|
Term
| Caustitutive (Types of Heterochromatin) |
|
Definition
|
|
Term
| Facultative (Types of Heterochromatin) |
|
Definition
| Shut down but can be opened again. |
|
|
Term
|
Definition
| When cell differenciates it needs to establish certain heterochromatin and euchromatin regions to commit to certain cell type. Heterochromatin linker: DNA shorter b/w nucleosomes. Euchromatin linker: DNA longer b/w nucleosomes. |
|
|
