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Molec. Cell Bio - Exam 1
Cell Basics, Proteins, Enzymes, DNA, RNA, Carbs, Lipids, Cell Membranes
20
Biology
Undergraduate 1
02/12/2013

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Cards

Term
When are organisms considered to be "living"?
Definition

When they

  1. Acquire, use energy
  2. Made of 1+ cells
  3. Process Information
  4. Capable of Replication
  5. Product of Evolution
Term
Where did most crucial chemical reactions take place?
Definition
  • Water-based environment
  • Hydrothermal vents
  • Catalyzed by minerals
  • Synthesis of complex molecules stimulated by heat, concentration
Term
Why is water polar?
Definition
  1. Oxygen is highly electronegative, draws electrons toward itself - slight negative charge on O, slight positive charge on both H.
Term
Why is water's hydrogen bonding important?
Definition
  1. Polarity creates weak, important hydrogen bonds b/n water molecules.
  2. Water = excellent solvent
Term
What is the narrow range of acidity containing almost all chemical reactions of living systems?
Definition
Physiological pH = 6.5-8.0
Term
pH is an expression of what?
Definition

the concentration of H+ in solution

pH = -log[H+]

Term
What is an Acid
Definition

A solution in which H+>OH-

An proton DONOR

Term
What is a Base?
Definition

A solution in which OH->H+

A proton ACCEPTOR

Term
What is a Buffer?
Definition
  • Resist changes in pH
  • Ability to accept or donate H+
  • don't ionize completely or dissociate
Term
[image]
Definition
  • Amino
  • Part of amino acids - build proteins
  • Act as a base, attract H+ --> NH3+

Term
[image]
Definition
  • 2 Kinds: [image]
  • Aldehydes contribute to some sugars
  • Aldehydes react w/ HR2 compounds to produce larger molecules
Term

[image]

 

Definition
  • Family: carboxylic Acids
  • Tends to act as acid - tends to lose H+ proton
Term
[image]
Definition
  • Hydroxyl
  • Make alcohols
  • HIGHLY POLAR - make compounds more soluble thru Hydrogen bonding with Water
Term
[image]
Definition
  • Contribute to Nucleic Acids, Lipids
  • When several are linked, breaking O-P bonds bn them release a lot of energy
Term
[image]
Definition
  • Sulfhydryl
  • Family: thiols
  • In proteins, can form disulfide (S-S) bonds, contribute to protein structure.
Term
Basic Protein structure
Definition
Polymers of amino acids, arranged in a linear chain
Term
What is TITIN?
Definition
  • super long protein
  • microscopic spring
  • pulls muscle fiber back in shape
Term
Basic structure of an un-ionized Amino Acid
Definition
[image]
Term
Polypeptides: components, synthesis
Definition
  • polymer of amino acids
  • linked by covalent bond called Peptide Bond
  • Dehydration reaction bn carboxyl of one and amino of other
Term
4 levels of Protein Structure
Definition
  1. Primary - can observe peptide bonds and functional groups
  2. Secondary - alpha helices, beta pleated sheets
  3. Tertiary - hydrogen bonding, van der Waals interactions, S-S bonding, ionic bonding between different sections within a strand (easily disturbed)
  4. Quaternary - overall shape, can see units/subunits
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