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A nonmitotic, or nondivision, form of cell death that occurs when cells die without attempting division during the interphase portion of the cell life cycle; programmed cell death |
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A classic method of displaying the sensitivity of a particular type of cell to radiation. |
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A double-strand break in same rung of the DNA molecular structure |
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namely, direct ionization and disruption of biomolecules, biologic damage occurs as a result of ionization of atoms on essential molecules produced by straight interaction with the incident radiation |
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A multistage process that first involves the production of free radicals that are created by the interaction of the radiation with water (H2O) molecules. |
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Law of Bergonié and Tribondeau |
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states that the radiosensitivity of cells is directly proportional to their reproductive activity and inversely proportional to their degree of differentiation. |
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Linear Energy Transfer (LET) |
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The average energy deposited per unit length of track. |
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The loss or change of a base in the DNA chain represents a ... |
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Operator Enhancment Ratio (OER) |
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the ratio of the radiation dose required to cause a particular biologic response of cells or organisms in an oxygen-deprived environment to the radiation dose required to cause an identical response under normal oxygenated conditions. |
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rupture one of its chemical bonds and possibly sever one of the sugar–phosphate chain side rails, or strands, of the ladder-like molecular structure (single-strand break) |
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radiation weighting factor (WR) |
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used to calculate the equivalent dose (EqD) to determine the ability of a dose of any kind of ionizing radiation to cause biologic damage. |
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relative biologic effectiveness (RBE) |
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RBE of the type of radiation being used is the ratio of the dose of a reference radiation (conventionally 250-kVp x-rays) to the dose of radiation of the type in question that is necessary to produce the same biologic reaction in a given experiment |
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states that when cell DNA is directly or indirectly inactivated by exposure to radiation, the cell will die. |
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x-rays and gamma rays can also be referred to as a stream of particles called photons. streams of particles called photons, each of which has no mass and no charge. |
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platelets, initiate blood clotting and prevent hemorrhage. |
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contains fibers that affect movement of an organ or part of the body. Since muscle tissue cells are highly specialized and do not divide, they are relatively insensitive to radiation. |
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generally results from exposure of cells to doses of ionizing radiation in the range of 1 to 10 Gyt. |
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alternative procedure to the use of a radiographic grid for reducing scattered radiation during certain examinations |
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the failure of the cell to start dividing on time. |
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Characteristics of ionizing radiation |
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