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- Differentiate pharmacodynamics (PD) from pharmacokinetics (PK).
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Understand drug-receptor interactions on a molecular level.
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- Explain the various types of agonists and antagonists.
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List the four basic concepts of pharmacokinetics. |
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Understand the physicochemical properties for drug transfer. |
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Understand the factors that modify drug absorption in relation to the method of drug administration and the effect on bioavailability. |
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- Understand the factors that modify drug distribution and its relationship to elimination.
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- Explain the factors that affect metabolism, and differentiate between Phase I and Phase II metabolism.
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- Understand the basic parameters of clearance pharmacokinetics.
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- Explain how pharmacokinetics impacts therapeutic dosing.
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Discuss the mechanisms of drug toxicity. |
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