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one of the first genomes sequenced |
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Presentation of frozen embryos available |
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Accessible, cheap, large embryos |
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Latin name for zebra fish |
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Can use gene knockouts and study consequences |
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Taught us more about developmental than any other |
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Good over-expression of gene products |
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Embryos available in large numbers, transparent and develop outside ovaries |
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Can silence gene function using RNAi |
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Robust, easily manipulated |
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Excellent imaging of embryos |
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Convenient and inexpensive |
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Excellent for micro-manipulation |
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Suitable for genetic and experimental manipulation |
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Large collection of mutant lines publicly available |
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Manipulation of gene expression via Gal4 UAS system |
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Loss of function by antisense 'morpholinio' oligonucleotides |
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Good imaging of embryo Can silence gene function by feeding larvae RNAi Full cell lineage analysis as in no other organism Presentation of frozen embryos possible |
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Can use gene knockouts and study consequences Imaging methodologies |
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Accessible, cheap, large embryos avaliable Robust, easily manipulated, Good for over-expression of gene products Reliable fate maps Loss of function by antisense 'morpholino' oligonucleotides |
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Embryo available in large numbers, transparent and develop outside Good for over-expression of gene products Loss of function by antisense 'morpholino' oligonucleotides |
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Convenient and inexpensive Excellent micromanipulation Good for over-expression of gene products Suitable for genetic and experimental manipulation |
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Taught us more about developmental than any other Large collection of mutant strains available to the public Manipulation of gene expression via Gal4 UAS system Can silence gene function by RNAi |
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