Term
| Special Features of E. Coli |
|
Definition
Small (1x2um)
20 min gen time
Easy to ID and isolate mutants |
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|
Term
| Main contributions of E. Coli |
|
Definition
Semi-conservative DNA
Elucidation of the genetic code
Spontaneous nature of mutations |
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|
Term
| Special features of Saccharomyces cerevisae = Yeast |
|
Definition
E. coli of eukaryotes
90 min cell cycle
Growth on liquid media or plates
Haploid or diploid |
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|
Term
| Main contributions of S. cerevisae |
|
Definition
Cell cycle = cdc mutants
Recombination
Gene interaction = 2 hybrid system, synthetic lethal screens |
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|
Term
| Special Features of Neurospora Crassa = Fungus |
|
Definition
Fast growing Eukaryote (.1.5um/sec)
Grows on minimal medium
Orded asci
Chromosomes are visible |
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|
Term
| Main contributions of N. Crassa |
|
Definition
Beadle and Tatum = one gene/one enzyme relationship
Model system for filamentous fungi affecting plants |
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|
Term
| Special features for Arabidoopsis Thaliana |
|
Definition
Small (<10 cm)
Can conduct large mutant hunts
Small genome (125 Mbp)
Short life cycle (6 weeks) |
|
|
Term
| Main contributions of A. Thaliana |
|
Definition
Model for plant genome architecture and evolution
Genetic control of plant development, including flower development = agriculture |
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|
Term
| Special features of Caenorhabditis elegans = nematode |
|
Definition
Transparent
Directly observe all stages of development
Small cell number (959, 1031)
Cell lineage is known
Total life cycle = 3.5 days |
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|
Term
| Main contributions of C. elegans |
|
Definition
| Study of development and programmed cell death |
|
|
Term
| Special features for Drosophila melanogaster |
|
Definition
Small (3mm)
Simple to raise
Quick to reproduce (12 days from larvae to adult)
POlytene chromosome banding pattern |
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|
Term
| Main contributions for Drosophila |
|
Definition
Development of chromosome theory
Development of gene mapping
Analysis of mutation, chromosome rearrangements
identification of homeotic and maternal effect mutations |
|
|
Term
| Special features of Mus musculus |
|
Definition
Genome similarity to human
Small mammal
Short generation time (10 weeks from birth to giving birth) |
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