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| less respiratory depression and physical dependency; ceiling effect, CNS effects and unpredictable response when added to an agonist |
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Term
| Buprenorphine (Buprenex, Subutex, Butrans) |
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Definition
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| High Doses = Addiction; Low Doses = Pain |
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Definition
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| to opioid receptors for up to 48 hours |
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| Antagonist used in opioid overdose, respiratory depression, reverse constipation or ileus without reversing analgesia |
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| Naltrexone (Revia, Vivitrol) |
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Definition
| Antagonist: analogue of naloxone that is orally absorbed; used for opioid dependency, ethanol dependency |
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Term
| Methylnaltrexone (Relistor) |
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Definition
| Antagonist: SC injected used for txt of opioid-induced constipation when response to laxative therapy has been insufficient |
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