Term
Plasma Cholinesterase
b)dec levels? |
|
Definition
found in plasma synthesized in liver.
Degrades anesthetics and cocaine
b) Hepatic Disease |
|
|
Term
Organophosphates
b) clinical symptoms? |
|
Definition
irrversible inhibitor of actelycholine esterase
dec aChestaerase
b) build up of acteylcholine
Atropine sulfate |
|
|
Term
| Increased synthesis of plasma cholinesterase |
|
Definition
nephrotic syndrome
Rapidly growing cells : liver recovery |
|
|
Term
Succinycl choline Drug
EFfects? |
|
Definition
Used to check Cholinesterase levels
Used to check for scoline apnea |
|
|
Term
|
Definition
defic in Choline esterase enzyme
due to Allelic Variability
|
|
|
Term
Allelic variation of CHe enzyme
E1U
E1A
E1F
E1S |
|
Definition
normal
resistant to inhib by dibucaine
resistant to inhib by floruide
silent |
|
|
Term
Aspartate Transaminase AST
Which cells have [high]?
|
|
Definition
liver
kidney
cardiac and skeletal Musc
erythrocytes |
|
|
Term
| Reasons for elevated levels of AST |
|
Definition
Normal in neonatal and hemolysis
High elevation:
mi
acute viral hepatitis
circulatory failure |
|
|
Term
| where is alanin transaminase found? ALT |
|
Definition
Liver
Kidney
skeletal and cardiac muscle |
|
|
Term
| when would you see and increase in ALT? |
|
Definition
circulatory failure andAcute viral Hepatitis
moderate incr:
liver cirrhosis
cholestatic jaundice
post heart surgery
skeltal muscle disease |
|
|
Term
| alkaline and acid phosphatases |
|
Definition
peak activity at pH 10 or 5
they are attached to cell membrane which suggests activity in membrane transport |
|
|
Term
Alkaline phosphate is found where?
B) When would you see physiological changes in alp |
|
Definition
liver
bone
intestine
placenta
b) Normal Pregenancy, High fat meals, diseases which affect billiary tract, infancy and childhood |
|
|
Term
Acid Phosphatase
a) where is found? |
|
Definition
prostate, liver, erythrocytes, bone, platelets
it is a Postate Specific Antigen
TUMOR MARKER
|
|
|
Term
which LDH will you see in Acute MI?
Actute hepatits? |
|
Definition
|
|
Term
CK enzymes seen in
Brain?
MI?
MD |
|
Definition
|
|
Term
Gama GT
where is it found?
higher in what sex? |
|
Definition
liver kidney pancrease
males
NOT found in Bone
|
|
|
Term
| when would you see and increase in G-GT |
|
Definition
alcohol or drugs
anticonvulsants, phenobarbitone and alchohol induced proliferation of er
cholestatic liver disease and hepatocellular damage |
|
|
Term
| what lines the intrahepatic ducts? |
|
Definition
|
|
Term
Amylase
Where is it found?
when would you see acute increase? |
|
Definition
pancrease and salivary glands
incresed in urine and serum during acute pancreatitis |
|
|
Term
| which enzymes would increase during an MI |
|
Definition
TROPONIN I
LDH1
AST
CK MB
Myglobin |
|
|
