Term
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Definition
| Pain receptors (FNE) that detect mechanical, thermal, and chemical changes above a certain threshold |
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Term
| What is nociceptive pain? |
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Definition
| direct activation of nocireceptors in skin or soft tissue due to tissue injury or inflammation |
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Term
| What is neuropathic pain? |
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Definition
| results from direct injury to nerves in PNS and CNS |
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Term
| Pricking, burning, aching, stinging, and soreness are all examples of what kind of pain? |
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Definition
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Term
| What is reflexive sympathetic dystrophy? |
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Definition
Rare disorder of sympathetic nervous system characterized by chronic, severe pain, inflammation, and edema
Also a neuropathic disorder |
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Term
| Examples of Neuropathic Pain |
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Definition
Burning/Electrical
RSD
Phantom Limb
Shingles
Disc hernation (spinal root damage) |
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Term
| Sensory component of pain |
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Definition
| analysis of noxious stimuli with regards to its location and intensity |
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Term
| Affective component of pain |
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Definition
| analysis of noxious stimuli with regards to its relationship to emotional responses, goals, desires, and individual expectations. |
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Term
| Cognitive component of pain |
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Definition
| analysis of noxious stimuli as it pertains to past experiences, comparing the pain to a previous injury and how that injury might prevent future actions or possibilities |
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Term
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Definition
level at which pain nerves will fire due to stimulation/activation
(The point that it begins to hurt) |
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Term
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Definition
Percieved intensityof pain point at which the person acts to stop the pain
Pain is variable and consistent from person to person!
(ie, athelete does not detect injury until end of game) |
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Term
| Thermal nociceptors are activated at what temperatures? |
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Definition
> 45 C (113 F)
<5 C (41 F) |
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Term
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Definition
| activated by pressure applied to skin |
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Term
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Definition
| activated by intense mechanical, chemical, or thermal stimuli |
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Term
| What is the theory in which nociceptors detect action potentials? |
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Definition
| nociceptor membrane contains proteins that convert TMC energy of noxious stimulus to depolarizing AP |
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Term
| Capsaicin (topical ointment, chili peppers, pepper spray) |
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Definition
Binds to pain and/or heat sensing neurons
TRPV1 protein --> Ca2+ channels below 37 C (body temp) --> sensation of heat |
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Term
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Definition
| Decreases perception of pain (topical ointments) |
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Term
| First order neurons of nociception |
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Definition
A-Delta
C Fibers
A-Beta II
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Term
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Definition
Thermal and mechanical
small diameter, thinly myelinated
CR: 5-30 m/s
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Term
| A-Delta receptors (sensations) |
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Definition
first pain
FAST
pulling away
sharp pain
stabbing
prickling
short duration
MECHANICAL STIMULUS
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Term
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Definition
Polymodal receptors (thermal >114F, <10, MC)
Small diameter, unmyelinated
CR: 0.5-2 m/s |
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Term
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Definition
Second pain
SLOW
dull
aching
unpleasant
persistent
long duration
detect heat/chemical stimuli |
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Term
Alpha-Beta II Receptors (A&P)
NOT a nociceptor!
non-noxious |
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Definition
Mechanoreceptor: pressure sensitivity (SKIN)
Large diameter
Myelinated
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Term
| Order in which mechano/noci- receptors are fired |
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Definition
From low to high intensity:
1.) A-Beta II(touch)
2.) A-Delta (sharp pain)
3.) C (dull pain)
Intensity of stimulus will determine which neurons are fired
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Term
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Definition
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Term
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Definition
from C fibers (help transmit info to SC and brain)
assoc. with inflammation process and intense, persistent, chronic pain
POTENT VASODILATOR! |
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