Midazolam HCL

(Versed)

Classification:          

Sedative

Hypnotic

Anticonvulsant

 Action:                      

Depresses the central nervous system

Relaxes skeletal muscle

Decreases patient recall (amnesic effect)

Suppress seizure activity

Indications:

Seizures (status epilepticus)

Sedation prior to:

       - synchronized Cardioversion

       - transcutaneious pacing

       - airway placement (RSI/NT)

Contraindications: 

Head injury

 Shock/Hypotension

  Glaucoma

Drug/Alcohol intoxication

Pt.’s  known to be taking:

Cardiazem, Verapamil, AIDS medications

Adverse Effects:

Cardiovascular

tachycardia

bradycardia

hypotension

PVCs

Respiratory

laryngospasm

depression

bronchospasm        

arrest

Neurological

blurred Vision

headache

drowsiness

Gastrointestinal

nausea/vomiting

Administration:                  

1 - 2mg slow IV/IO over 2-3 minutes or MADD.

(titrate to suppress seizure activity or until sedation

occurs)  May repeat in 1mg increments to a maximum of 8mg.

Pediatrics:                           

Under 12 years        

0.05mg/kg slow IV/IO over 2-3 minutes (titrate to suppress seizure activity or until sedation occurs). Repeat in 0.05mg increments to a max dose of 0.2mg/kg.

Over 12 years           

Adult dosage

Onset: 

Duration:                  

Onset:                         1 - 3 minutes

Duration:                   2 - 4 hours

Precautions:            

Use cautiously in patients with impaired respiratory function, COPD, renal failure, or liver disease.

Monitor patient respiratory status and be prepared to

provide support.